- Oral antiviral therapy for prevention of genital herpes outbreaks in immunocompetent and nonpregnant patients
Cochrane Systematic Reviews, 30-Jul-2014
Genital herpes is caused by herpes simplex virus 1 (HSV-1) or 2 (HSV-2). Some infected people experience outbreaks of genital herpes, typically, characterized by vesicular and erosive localized painful genital lesions. - Oral aspirin for treating venous leg ulcers
Cochrane Systematic Reviews, 15-Feb-2016
Venous leg ulcers (VLUs) or varicose ulcers are the final stage of chronic venous insufficiency (CVI), and are the most common type of leg ulcer. The development of VLUs on ankles and lower legs can occur spontaneously or after minor trauma. The ulcers ar - Oral Astragalus (Huang qi) for preventing frequent episodes of acute respiratory tract infection in children
Cochrane Systematic Reviews, 27-Nov-2016
Acute respiratory tract infections (ARTIs) are common in children and can involve both upper and lower airways. Many children experience frequent ARTI episodes or recurrent respiratory tract infections (RRTIs) in early life, which creates challenges for p - Oral beta-blockers for mild to moderate hypertension during pregnancy
Cochrane Systematic Reviews, 5-Jul-2012
Antihypertensives, such as beta-blockers, are used for pregnancy hypertension in the belief these will improve outcome for mother and baby. - Oral betamimetics for maintenance therapy after threatened preterm labour
Cochrane Systematic Reviews, 14-Nov-2012
Some women who have threatened to give birth prematurely, subsequently settle. They may then take oral tocolytic maintenance therapy to prevent preterm birth and to prolong gestation. - Oral budesonide for induction of remission in ulcerative colitis
Cochrane Systematic Reviews, 22-Oct-2015
Corticosteroids are first-line therapy for induction of remission in ulcerative colitis. Although corticosteroids may improve symptoms, they have significant adverse effects. Steroids which act topically, with less systemic side-effects may be more desira - Oral contraceptive pill, progestogen or oestrogen pretreatment for ovarian stimulation protocols for women undergoing assisted reproductive techniques
Cochrane Systematic Reviews, 9-Aug-2017
Among subfertile women undergoing assisted reproductive technology (ART), hormone pills given before ovarian stimulation may improve outcomes. - Oral corticosteroids for bronchiectasis (stable and acute exacerbations)
Cochrane Systematic Reviews, 10-May-2011
Inflammation plays a significant role in the pathophysiology of bronchiectasis. Two small studies have shown small benefits from inhaled corticosteroids and oral corticosteroids may be of benefit in bronchiectasis - Oral corticosteroids for stable chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 29-Mar-2009
Chronic obstructive pulmonary disease (COPD) is a common chronic lung disorder, usually related to cigarette smoking, representing a major and increasing cause of morbidity and mortality. It is defined "as a disease state characterized by airflow limitati - Oral dextrose gel for the treatment of hypoglycaemia in newborn infants
Cochrane Systematic Reviews, 2-May-2016
Neonatal hypoglycaemia, a common condition, can be associated with brain injury. It is frequently managed by providing infants with an alternative source of glucose, given enterally with formula or intravenously with dextrose solution. This often requires - Oral direct thrombin inhibitors or oral factor Xa inhibitors for the treatment of deep vein thrombosis
Cochrane Systematic Reviews, 24-Aug-2015
Deep vein thrombosis (DVT) is a condition in which a clot forms in the deep veins, most commonly of the leg. It occurs in approximately 1 in 1,000 people. If left untreated, the clot can travel up to the lungs and cause a potentially life-threatening pulm - Oral direct thrombin inhibitors or oral factor Xa inhibitors for the treatment of pulmonary embolism
Cochrane Systematic Reviews, 16-Dec-2016
Pulmonary embolism is a potentially life-threatening condition in which a clot can travel from the deep veins, most commonly in the leg, up to the lungs. Previously, a pulmonary embolism was treated with the anticoagulants heparin and vitamin K antagonist - Oral H1 antihistamines as ‘add-on’ therapy to topical treatment for eczema
Cochrane Systematic Reviews, 15-Jan-2019
The symptoms of eczema can lead to sleeplessness and fatigue and may have a substantial impact on quality of life. Use of oral H1 antihistamines (H1 AH) as adjuvant therapy alongside topical agents is based on the idea that combining the anti-inflammatory - Oral health educational interventions for nursing home staff and residents
Cochrane Systematic Reviews, 29-Sep-2016
Associations between nursing home residents’ oral health status and quality of life, respiratory tract infections, and nutritional status have been reported. Educational interventions for nurses or residents, or both, focusing on knowledge and skills rela - Oral herbal therapies for treating osteoarthritis
Cochrane Systematic Reviews, 4-Apr-2016
Medicinal plant products are used orally for treating osteoarthritis. Although their mechanisms of action have not yet been elucidated in full detail, interactions with common inflammatory mediators provide a rationale for using them to treat osteoarthrit - Oral immunotherapy for milk allergy
Cochrane Systematic Reviews, 16-Oct-2012
The mainstay of treatment of IgE-mediated cow milk allergy (IMCMA) is an avoidance diet, which is especially difficult with a ubiquitous food like milk. Milk oral immunotherapy (MOIT) may be an alternative treatment, through desensitization or induction o - Oral medications including clomiphene citrate or aromatase inhibitors with gonadotropins for controlled ovarian stimulation in women undergoing in vitro fertilisation
Cochrane Systematic Reviews, 2-Nov-2017
Gonadotropins are the most commonly used medications for controlled ovarian stimulation in in vitro fertilisation (IVF). However, they are expensive and invasive, and are associated with the risk of ovarian hyperstimulation syndrome (OHSS). Recent calls f - Oral methylxanthines for bronchiectasis
Cochrane Systematic Reviews, 8-Mar-2010
Bronchiectasis is characterised by chronic sputum production, bronchial wall dilation, recurrent infection and airflow limitation. Methylxanthines are used in the management of airflow limitation associated with asthma and COPD, where they are also purpor - Oral non steroid anti-inflammatories for children and adults with bronchiectasis
Cochrane Systematic Reviews, 23-Mar-2009
Bronchiectasis is increasing recognised as a co-morbidity in many respiratory illness. Anti inflammatory drugs may reduce the inflammatory cascade and thus reduce symptoms and slow long term pulmonary decline. - Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors
Cochrane Systematic Reviews, 2-Jul-2014
Iron deficiency is a significant cause of deferral in people wishing to donate blood. If iron removed from the body through blood donation is not replaced, then donors may become iron deficient. All donors are screened at each visit for low haemoglobin (H
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