- Reflectance confocal microscopy for diagnosing cutaneous melanoma in adults
Cochrane Systematic Reviews, 4-Dec-2018
Melanoma has one of the fastest rising incidence rates of any cancer. It accounts for a small percentage of skin cancer cases but is responsible for the majority of skin cancer deaths. Early detection and treatment is key to improving survival; however, a - Reflectance confocal microscopy for diagnosing keratinocyte skin cancers in adults
Cochrane Systematic Reviews, 4-Dec-2018
Early accurate detection of all skin cancer types is important to guide appropriate management and improve morbidity and survival. Basal cell carcinoma (BCC) is usually a localised skin cancer but with potential to infiltrate and damage surrounding tissue - Regimens of fetal surveillance for impaired fetal growth
Cochrane Systematic Reviews, 13-Jun-2012
Policies and protocols for fetal surveillance in the pregnancy where impaired fetal growth is suspected vary widely, with numerous combinations of different surveillance methods. - Regimens of fetal surveillance of suspected large‐for‐gestational‐age fetuses for improving health outcomes
Cochrane Systematic Reviews, 5-Apr-2016
Policies and protocols vary widely for fetal surveillance in a pregnancy where the fetus is suspected to be large-for-gestational-age (LGA). All ultimately culminate in decisions about the mode and timing of birth. LGA is known to be associated with incre - Regimens of less than six months for treating tuberculosis
Cochrane Systematic Reviews, 25-Oct-1999
WHO recommends 6 months of treatment in TB programmes. - Regimens of ultrasound surveillance for twin pregnancies for improving outcomes
Cochrane Systematic Reviews, 7-Nov-2017
Increased ultrasound surveillance of twin pregnancies has become accepted practice due to the higher risk of complications. There is no current consensus however as to the method and frequency of ultrasound monitoring that constitutes optimal care. - Regimens of vitamin D supplementation for women during pregnancy
Cochrane Systematic Reviews, 3-Oct-2019
Vitamin D deficiency during pregnancy increases the risk of pre-eclampsia, gestational diabetes, preterm birth, and low birthweight. In a previous Cochrane Review we found that supplementing pregnant women with vitamin D alone compared to no vitamin D sup - Regional (spinal, epidural, caudal) versus general anaesthesia in preterm infants undergoing inguinal herniorrhaphy in early infancy
Cochrane Systematic Reviews, 9-Jun-2015
With improvements in neonatal intensive care, more preterm infants are surviving the neonatal period and presenting for surgery in early infancy. Inguinal hernia is the most common condition requiring early surgery, appearing in 38% of infants whose birth - Regional analgesia for improvement of long‐term functional outcome after elective large joint replacement
Cochrane Systematic Reviews, 13-Aug-2015
Regional analgesia is more effective than conventional analgesia for controlling pain and may facilitate rehabilitation after large joint replacement in the short term. It remains unclear if regional anaesthesia improves functional outcomes after joint re - Regional Cerebral Blood Flow Single Photon Emission Computed Tomography for detection of Frontotemporal dementia in people with suspected dementia
Cochrane Systematic Reviews, 23-Jun-2015
In the UK, dementia affects 5% of the population aged over 65 years and 25% of those over 85 years. Frontotemporal dementia (FTD) represents one subtype and is thought to account for up to 16% of all degenerative dementias. Although the core of the diagno - Regional versus general anaesthesia for caesarean section
Cochrane Systematic Reviews, 17-Oct-2012
Regional anaesthesia (RA) and general anaesthesia (GA) are commonly used for caesarean section (CS) and both have advantages and disadvantages. It is important to clarify what type of anaesthesia is more efficacious. - Regular (ICSI) versus ultra‐high magnification (IMSI) sperm selection for assisted reproduction
Cochrane Systematic Reviews, 21-Feb-2020
Subfertility is a condition found in up to 15% of couples of reproductive age. Gamete micromanipulation, such as intracytoplasmic sperm injection (ICSI), is very useful for treating couples with compromised sperm parameters. An alternative method of sperm - Regular long‐term red blood cell transfusions for managing chronic chest complications in sickle cell disease
Cochrane Systematic Reviews, 25-Oct-2019
Sickle cell disease is a genetic haemoglobin disorder, which can cause severe pain, significant end-organ damage, pulmonary complications, and premature death. Sickle cell disease is one of the most common severe monogenic disorders in the world, due to t - Regular self‐examination or clinical examination for early detection of breast cancer
Cochrane Systematic Reviews, 22-Apr-2003
Breast self-examination and clinical breast examination have been promoted for many years as general screening methods to diagnose breast cancer at an early stage in order to decrease morbidity and mortality. The possible benefits and harms remain unclear - Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an inhaled corticosteroid for chronic asthma: serious adverse events
Cochrane Systematic Reviews, 14-Apr-2021
Asthma is characterised by chronic inflammation of the airways and recurrent exacerbations with wheezing, chest tightness, and cough. Treatment with inhaled steroids and bronchodilators can result in good control of symptoms, prevention of further morbidi - Regular treatment with formoterol for chronic asthma: serious adverse events
Cochrane Systematic Reviews, 18-Apr-2012
Epidemiological evidence has suggested a link between beta2-agonists and increases in asthma mortality. There has been much debate about possible causal links for this association, and whether regular (daily) long-acting beta2-agonists are safe. - Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events
Cochrane Systematic Reviews, 14-Mar-2012
An increase in serious adverse events with both regular formoterol and regular salmeterol in chronic asthma has been demonstrated in previous Cochrane reviews. - Regular treatment with long acting beta agonists versus daily regular treatment with short acting beta agonists in adults and children with stable asthma
Cochrane Systematic Reviews, 22-Jul-2002
Selective beta-adrenergic agonists for use in asthma are: short acting (2 to 6 hours) and long acting (> 12 hours). There has been little controversy about using short acting beta-agonists intermittently, but long acting beta-agonists are used regularly, - Regular treatment with salmeterol for chronic asthma: serious adverse events
Cochrane Systematic Reviews, 16-Jul-2008
Epidemiological evidence has suggested a link between beta2-agonists and increases in asthma mortality. There has been much debate about possible causal links for this association, and whether regular (daily) long-acting beta2-agonists are safe. - Rehabilitation after lumbar disc surgery
Cochrane Systematic Reviews, 14-Mar-2014
Several rehabilitation programmes are available for individuals after lumbar disc surgery.
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