- Single versus double volume exchange transfusion in jaundiced newborn infants
Cochrane Systematic Reviews, 23-Sep-2008
Double volume exchange transfusion is commonly used in newborns with severe jaundice in order to prevent kernicterus and other toxicity related to hyperbilirubinemia. Most commonly, exchange transfusions are used in infants with rhesus hemolytic disease. - Single versus multiple visits for endodontic treatment of permanent teeth
Cochrane Systematic Reviews, 30-Nov-2016
Root canal treatment (RoCT), or endodontic treatment, is a common procedure in dentistry. The main indications for RoCT are irreversible pulpitis and necrosis of the dental pulp caused by carious processes, tooth cracks or chips, or dental trauma. Success - Single versus two layer suturing for closing the uterine incision at Caesarean section
Cochrane Systematic Reviews, 3-May-2008
A single layer closure might save operating time, disrupt less tissue, introduce less foreign material into the wound, and thus result in less post operative morbidity. - Single, double or multiple-injection techniques for non-ultrasound guided axillary brachial plexus block in adults undergoing surgery of the lower arm
Cochrane Systematic Reviews, 31-Aug-2016
Regional anaesthesia comprising axillary block of the brachial plexus is a common anaesthetic technique for distal upper limb surgery. This is an update of a review first published in 2006 and previously updated in 2011 and 2013. - Single-dose intravenous diclofenac for acute postoperative pain in adults
Cochrane Systematic Reviews, 11-Jan-2019
Postoperative administration of non-steroidal anti-inflammatory drugs (NSAIDs) reduces patient opioid requirements and, in turn, reduces the incidence and severity of opioid-induced adverse events (AEs). - Single-dose intravesical chemotherapy after nephroureterectomy for upper tract urothelial carcinoma
Cochrane Systematic Reviews, 17-May-2019
Single-dose, postoperative intravesical chemotherapy reduces the risk of bladder cancer recurrence after transurethral resection of bladder tumours. However, there is limited evidence whether single-dose intravesical chemotherapy is similarly effective at - Single-incision sling operations for urinary incontinence in women
Cochrane Systematic Reviews, 25-Jul-2017
Urinary incontinence has been shown to affect up to 50% of women. Studies in the USA have shown that up to 80% of these women have an element of stress urinary incontinence. This imposes significant health and economic burden on society and the women affe - Sinonasal debridement versus no debridement for the postoperative care of patients undergoing endoscopic sinus surgery
Cochrane Systematic Reviews, 5-Nov-2018
Endoscopic sinus surgery (ESS) is often recommended for symptomatic patients with recurrent acute or chronic rhinosinusitis who have failed conservative treatment. Postoperative care has been felt to be critical for both maintaining the surgical patency o - Six months therapy for tuberculous meningitis
Cochrane Systematic Reviews, 19-Sep-2017
Tuberculous meningitis (TBM) is the main form of tuberculosis that affects the central nervous system and is associated with high rates of death and disability. Most international guidelines recommend longer antituberculous treatment (ATT) regimens for TB - Six-month therapy for abdominal tuberculosis
Cochrane Systematic Reviews, 28-Oct-2016
Tuberculosis (TB) of the gastrointestinal tract and any other organ within the abdominal cavity is abdominal TB, and most guidelines recommend the same six-month regimen used for pulmonary TB for people with this diagnosis. However, some physicians are co - Skin antisepsis for reducing central venous catheter-related infections
Cochrane Systematic Reviews, 12-Jul-2016
The central venous catheter (CVC) is a device used for many functions, including monitoring haemodynamic indicators and administering intravenous medications, fluids, blood products and parenteral nutrition. However, as a foreign object, it is susceptible - Skin grafting and tissue replacement for treating foot ulcers in people with diabetes
Cochrane Systematic Reviews, 9-Mar-2017
Foot ulceration is a major problem in people with diabetes and is the leading cause of hospitalisation and limb amputations. Skin grafts and tissue replacements can be used to reconstruct skin defects for people with diabetic foot ulcers in addition to pr - Skin grafting for venous leg ulcers
Cochrane Systematic Reviews, 5-Dec-2012
Venous leg ulceration is a recurrent, chronic, disabling condition. It affects up to one in 100 people at some time in their lives. Standard treatments are simple dressings and compression bandages or stockings. Sometimes, despite treatment, ulcers remain - Skin patch and vaginal ring versus combined oral contraceptives for contraception
Cochrane Systematic Reviews, 13-Mar-2013
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to - Skin preparation for preventing infection following caesarean section
Cochrane Systematic Reviews, 19-Oct-2018
The risk of maternal mortality and morbidity (particularly postoperative infection) is higher for caesarean section (CS) than for vaginal birth. With the increasing rate of CS, it is important to minimise the risks to the mother as much as possible. This - Skin preparation with alcohol versus alcohol followed by any antiseptic for preventing bacteraemia or contamination of blood for transfusion
Cochrane Systematic Reviews, 11-Feb-2015
Blood for transfusion may become contaminated at any point between collection and transfusion and may result in bacteraemia (the presence of bacteria in the blood), severe illness or even death for the blood recipient. Donor arm skin is one potential sour - Skin-to-skin care for procedural pain in neonates
Cochrane Systematic Reviews, 7-Feb-2017
Skin-to-skin care (SSC), often referred to as 'kangaroo care' (KC) due to its similarity with marsupial behaviour of ventral maternal-infant contact, is one non-pharmacological intervention for pain control in infants. - Sleep positioning systems for children with cerebral palsy
Cochrane Systematic Reviews, 27-Oct-2015
Sleep positioning systems can be prescribed for children with cerebral palsy to help reduce or prevent hip migration, provide comfort to ease pain and/or improve sleep. As sleep disturbance is common in children with developmental disabilities, with impac - Sliding scale insulin for non-critically ill hospitalised adults with diabetes mellitus
Cochrane Systematic Reviews, 27-Nov-2018
Diabetes mellitus is a metabolic disorder resulting from a defect in insulin secretion, function, or both. Hyperglycaemia in non-critically ill hospitalised people is associated with poor clinical outcomes (infections, prolonged hospital stay, poor wound - Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants
Cochrane Systematic Reviews, 30-Aug-2017
Early enteral feeding practices are potentially modifiable risk factors for necrotising enterocolitis (NEC) in very preterm or very low birth weight (VLBW) infants. Observational studies suggest that conservative feeding regimens, including slowly advanci
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