- Oestrogens for treatment or prevention of pelvic organ prolapse in postmenopausal women
Cochrane Systematic Reviews, 3-Aug-2010
Pelvic organ prolapse is common and can be detected in up to 50% of parous women although many are asymptomatic. Oestrogen preparations are used to improve vaginal thinning (atrophy). It is possible that oestrogens, alone or in conjunction with other inte - Off-pump versus on-pump coronary artery bypass grafting for ischaemic heart disease
Cochrane Systematic Reviews, 29-Feb-2012
Coronary artery bypass grafting (CABG) is performed both without and with cardiopulmonary bypass, referred to as off-pump and on-pump CABG respectively. However, the preferable technique is unclear. - Oil-soluble versus water-soluble media for assessing tubal patency with hysterosalpingography or laparoscopy in subfertile women
Cochrane Systematic Reviews, 17-Jul-2008
There has been debate in the literature for more than 40 years as to whether flushing of the Fallopian tubes enhances fertility and whether this presumed therapeutic effect is greater with oil-soluble media than with water-soluble media. - Olanzapine for the prevention and treatment of cancer-related nausea and vomiting in adults
Cochrane Systematic Reviews, 20-Sep-2018
Olanzapine as an antiemetic represents a new use of an antipsychotic drug. People with cancer may experience nausea and vomiting whilst receiving chemotherapy or radiotherapy, or whilst in the palliative phase of illness. - Olanzapine IM or velotab for acutely disturbed/agitated people with suspected serious mental illnesses
Cochrane Systematic Reviews, 4-Aug-2009
People presenting with agitated or violent behaviour thought to be due to severe mental illness may require urgent pharmacological tranquillisation. Several preparations of olanzapine, an antipsychotic drug, are now being used for management of such agita - Olanzapine versus other atypical antipsychotics for schizophrenia
Cochrane Systematic Reviews, 1-May-2013
In many countries of the industrialised world second generation ("atypical") antipsychotics have become the first line drug treatment for people with schizophrenia. The question as to whether, and if so how much, the effects of the various second generati - Omalizumab for asthma in adults and children
Cochrane Systematic Reviews, 18-Dec-2013
Asthma is a respiratory (airway) condition that affects an estimated 300 million people worldwide and is associated with significant morbidity and mortality. Omalizumab is a monoclonal antibody that binds and inhibits free serum immunoglobulin E (IgE). It - Omega 3 fatty acid for the prevention of cognitive decline and dementia
Cochrane Systematic Reviews, 14-Aug-2012
Evidence from observational studies suggests that diets high in omega-3 long-chain polyunsaturated fatty acids (PUFA) may protect people from cognitive decline and dementia. The strength of this potential protective effect has recently been tested in rand - Omega 3 fatty acids (fish oil) for maintenance of remission in Crohn's disease
Cochrane Systematic Reviews, 25-Jun-2014
The anti-inflammatory effects of n-3 (omega-3 fatty acids, fish oil) have been suggested to be beneficial in chronic inflammatory disorders such as inflammatory bowel disease. This review is an update of a previously published Cochrane review. - Omega 3 fatty acids (fish oil) for maintenance of remission in ulcerative colitis
Cochrane Systematic Reviews, 27-May-2008
Omega-3 fatty acids (n-3, fish oil) have been shown to have anti-inflammatory properties. Therefore, n-3 therapy may be beneficial in chronic inflammatory disorders such as ulcerative colitis. - Omega-3 fatty acid addition during pregnancy
Cochrane Systematic Reviews, 15-Nov-2018
Higher intakes of foods containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA), such as fish, during pregnancy have been associated with longer gestations and improved perinatal outcomes. This is an update of a review that was first published - Omega-3 fatty acids for bipolar disorder
Cochrane Systematic Reviews, 2-Nov-2008
Bipolar disorder is a complex psychiatric disorder and is amongst the top thirty causes of worldwide disability. Mood stabilisers are the primary pharmacological intervention, both in the treatment of acute episodes and in prophylaxis. There is, however, - Omega-3 fatty acids for depression in adults
Cochrane Systematic Reviews, 19-Dec-2016
Major depressive disorder (MDD) is highly debilitating, difficult to treat, has a high rate of recurrence, and negatively impacts the individual and society as a whole. One emerging potential treatment for MDD is n-3 polyunsaturated fatty acids (n-3PUFAs) - Omega-3 fatty acids for dialysis vascular access outcomes in patients with chronic kidney disease
Cochrane Systematic Reviews, 14-Nov-2018
Maintaining long-term vascular access patency is necessary for high quality haemodialysis (HD) treatment of patients with the terminal and most serious stage of chronic kidney disease (CKD) - end-stage kidney disease (ESKD). Oral supplementation with omeg - Omega-3 fatty acids for intermittent claudication
Cochrane Systematic Reviews, 3-Jul-2013
Omega-3 fatty acids have been used in the treatment and prevention of coronary artery disease although current evidence suggests they may be of limited benefit. Peripheral arterial disease and coronary artery disease share a similar pathogenesis so omega- - Omega-3 fatty acids supplementation for autism spectrum disorders (ASD)
Cochrane Systematic Reviews, 31-Oct-2011
It has been suggested that impairments associated with autism spectrum disorders (ASD) may be partially explained by deficits of omega-3 fatty acids, and that supplementation of these essential fatty acids may lead to improvement of symptoms. - Omega-3 polyunsaturated fatty acids (PUFA) for type 2 diabetes mellitus
Cochrane Systematic Reviews, 4-Nov-2008
People with type 2 diabetes mellitus are at increased risk from cardiovascular disease. Dietary omega-3 polyunsaturated fatty acids (PUFAs) are known to reduce triglyceride levels, but their impact on cholesterol levels, glycemic control and vascular outc - Omentoplasty for oesophagogastrostomy after oesophagectomy
Cochrane Systematic Reviews, 1-Oct-2014
Oesophagectomy followed by oesophagogastrostomy is the preferred treatment for early-stage oesophageal cancer. It carries the risk of anastomotic leakage after oesophagogastric anastomosis, which causes considerable morbidity and mortality and is one of t - Once-daily long-acting beta₂-agonists/inhaled corticosteroids combined inhalers versus inhaled long-acting muscarinic antagonists for people with chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 6-Aug-2018
Three classes of inhaler medication are used to manage chronic obstructive pulmonary disease (COPD): long-acting beta2-agonists (LABA); long-acting muscarinic antagonists (LAMA); and inhaled corticosteroids (ICS). To encourage patient adherence, two class - One dose per day compared to multiple doses per day of gentamicin for treatment of suspected or proven sepsis in neonates
Cochrane Systematic Reviews, 6-Feb-2017
Animal studies and trials in older children and adults suggest that a 'one dose per day' regimen of gentamicin is superior to a 'multiple doses per day' regimen.
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