- Nedocromil sodium for chronic asthma in children
Cochrane Systematic Reviews, 9-Nov-2009
Currently inhaled corticosteroids are the main stay in the maintenance treatment of chronic asthma in children. Although inhaled corticosteroids play a crucial role in the management of childhood asthma, the long-term side effects of inhaled corticosteroi - Nedocromil sodium for preventing exercise-induced bronchoconstriction
Cochrane Systematic Reviews, 29-Mar-2009
Exercise-induced bronchoconstriction (EIB) following strenuous physical exertion afflicts many people. It can be the cause of sub-optimal performance, symptoms such as cough, dyspnea, wheeze and chest tightness, and can lead people to avoid physical activ - Nedocromil sodium versus sodium cromoglycate for preventing exercise-induced bronchoconstriction
Cochrane Systematic Reviews, 12-Aug-2008
Nedocromil sodium and sodium cromoglycate inhaled shortly before exercise appear to reduce the severity of exercise-induced bronchoconstriction. There is some debate over which drug may be more effective. - Needle aspiration versus intercostal tube drainage for pneumothorax in the newborn
Cochrane Systematic Reviews, 31-Jan-2019
Pneumothorax occurs more frequently in the neonatal period than at any other time of life and is associated with increased mortality and morbidity. It can be treated with either aspiration with a syringe (using a needle or an angiocatheter) or a chest tub - Needle syringe programmes and opioid substitution therapy for preventing hepatitis C transmission in people who inject drugs
Cochrane Systematic Reviews, 14-Sep-2017
Needle syringe programmes and opioid substitution therapy for preventing hepatitis C transmission in people who inject drugs - Negative pressure wound therapy for open traumatic wounds
Cochrane Systematic Reviews, 3-Jul-2018
Traumatic wounds (wounds caused by injury) range from abrasions and minor skin incisions or tears, to wounds with extensive tissue damage or loss as well as damage to bone and internal organs. Two key types of traumatic wounds considered in this review ar - Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus
Cochrane Systematic Reviews, 16-Oct-2018
Foot wounds in people with diabetes mellitus (DM) are a common and serious global health issue. People with DM are prone to developing foot ulcers and, if these do not heal, they may also undergo foot amputation surgery resulting in postoperative wounds. - Negative pressure wound therapy for treating leg ulcers
Cochrane Systematic Reviews, 2-Dec-2016
Leg ulcers are open skin wounds that occur between the ankle and the knee that can last weeks, months or even years and are a consequence of arterial or venous valvular insufficiency. Negative pressure wound therapy (NPWT) is a technology that is currentl - Negative pressure wound therapy for treating pressure ulcers
Cochrane Systematic Reviews, 2-Jun-2015
Pressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. Negative pressure wound therapy (NPWT) is a treatment option for pressure ulcers; a clear, curren - Negative pressure wound therapy for treating surgical wounds healing by secondary intention
Cochrane Systematic Reviews, 29-May-2015
Following surgery, incisions are usually closed by fixing the edges together with sutures (stitches), staples, adhesive glue or clips. This process helps the cut edges heal together and is called 'healing by primary intention'. However, not all incised wo - Neo-adjuvant and adjuvant hormone therapy for localised and locally advanced prostate cancer
Cochrane Systematic Reviews, 3-Jun-2009
Hormone therapy for early prostate cancer has demonstrated an improvement in clinical and pathological variables, but not always an improvement in overall survival. We performed a systematic review of both adjuvant and neo-adjuvant hormone therapy combine - Neo-adjuvant chemotherapy for invasive bladder cancer
Cochrane Systematic Reviews, 17-Jan-2012
Controversy exists as to whether neoadjuvant chemotherapy improves survival in patients with invasive bladder cancer, despite randomised controlled trials (RCTs) involving over 3000 patients. - Neoadjuvant chemotherapy for locally advanced cervix cancer
Cochrane Systematic Reviews, 11-Feb-2015
The impact of neoadjuvant chemotherapy in the treatment of locally advanced cervical cancer remains uncertain. - Neoadjuvant chemotherapy versus none for resectable gastric cancer
Cochrane Systematic Reviews, 29-Oct-2008
Gastric cancer is a major cause of cancer death, and many patients are only diagnosed when the cancer has reached an advanced stage. Neoadjuvant chemotherapy (NAC), that is, chemotherapy administered shortly before surgical treatment, could provide a meth - Neonatal interventions for preventing cerebral palsy: an overview of Cochrane Systematic Reviews
Cochrane Systematic Reviews, 19-Jun-2018
Cerebral palsy is an umbrella term that encompasses disorders of movement and posture attributed to non-progressive disturbances occurring in the developing foetal or infant brain. As there are diverse risk factors and aetiologies, no one strategy will pr - Neonatal screening for sickle cell disease
Cochrane Systematic Reviews, 29-Sep-2010
Sickle cell disease is an inherited disorder that occurs throughout the world with its highest incidence in areas of Africa where malaria is endemic. It affects up to 1 in 60 infants born in some areas of Africa. There are a number of potentially serious - Neonatal vitamin A supplementation for the prevention of mortality and morbidity in term neonates in low and middle income countries
Cochrane Systematic Reviews, 24-Feb-2017
Vitamin A deficiency is a major public health problem in low and middle income countries. Vitamin A supplementation in children six months of age and older has been found to be beneficial, but no effect of supplementation has been noted for children betwe - Neostigmine for reversal of neuromuscular block in paediatric patients
Cochrane Systematic Reviews, 30-Apr-2014
Residual neuromuscular block is associated with serious postoperative complications. Some anaesthesiologists use neostigmine to reverse neuromuscular blockade for all paediatric surgical patients. However, the incidence of residual neuromuscular block may - Nerve blocks for initial pain management of femoral fractures in children
Cochrane Systematic Reviews, 13-Dec-2013
Children and adolescents with femoral fractures are almost always admitted to hospital. They invariably start their hospital experience in the Emergency Department, often requiring transfer to a specialist children's hospital. They require analgesia or an - Nerve-sparing radical hysterectomy compared to standard radical hysterectomy for women with early stage cervical cancer (stage Ia2 to IIa)
Cochrane Systematic Reviews, 11-Feb-2019
Radical hysterectomy is one of the standard treatments for stage Ia2 to IIa cervical cancer. Bladder dysfunction caused by disruption of the pelvic autonomic nerves is a common complication following standard radical hysterectomy and can affect quality of
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