- Nebulised deoxyribonuclease for viral bronchiolitis in children younger than 24 months
Cochrane Systematic Reviews, 9-Oct-2012
Bronchiolitis is one of the most common respiratory problems in the first year of life. The sputum of infants with bronchiolitis has increased deoxyribonucleic acid (DNA) content, leading to mucous plugging and airway obstruction. Recombinant human deoxyr - Nebulised hypertonic saline for cystic fibrosis
Cochrane Systematic Reviews, 19-Sep-2018
Impaired mucociliary clearance characterises lung disease in cystic fibrosis (CF). Hypertonic saline enhances mucociliary clearance and may lessen the destructive inflammatory process in the airways. This is an update of a previously published review. - Nebulised morphine for severe interstitial lung disease
Cochrane Systematic Reviews, 1-Jun-2011
The evidence to support the use of nebulized morphine to improve dyspnoea and exercise limitation in terminally ill patients with chronic lung disease is conflicting. - Nebulised surfactant in preterm infants with or at risk of respiratory distress syndrome
Cochrane Systematic Reviews, 11-Sep-2012
Nebulised surfactant has the potential to deliver surfactant to the infant lung with the goal of avoiding endotracheal intubation and ventilation, ventilator-induced lung injury and bronchopulmonary dysplasia (BPD). - Nebuliser systems for drug delivery in cystic fibrosis
Cochrane Systematic Reviews, 27-Mar-2013
Nebuliser systems are used to deliver medications to control the symptoms and the progression of lung disease in people with cystic fibrosis. Many types of nebuliser systems are available for use with various medications; however, there has been no previo - Nebulized epinephrine for croup in children
Cochrane Systematic Reviews, 2-Oct-2013
Croup is a common childhood illness characterized by barky cough, stridor, hoarseness and respiratory distress. Children with severe croup are at risk for intubation. Nebulized epinephrine may prevent intubation. - Nedocromil sodium for chronic asthma in children
Cochrane Systematic Reviews, 9-Nov-2009
Currently inhaled corticosteroids are the main stay in the maintenance treatment of chronic asthma in children. Although inhaled corticosteroids play a crucial role in the management of childhood asthma, the long-term side effects of inhaled corticosteroi - Nedocromil sodium for preventing exercise-induced bronchoconstriction
Cochrane Systematic Reviews, 29-Mar-2009
Exercise-induced bronchoconstriction (EIB) following strenuous physical exertion afflicts many people. It can be the cause of sub-optimal performance, symptoms such as cough, dyspnea, wheeze and chest tightness, and can lead people to avoid physical activ - Nedocromil sodium versus sodium cromoglycate for preventing exercise-induced bronchoconstriction
Cochrane Systematic Reviews, 12-Aug-2008
Nedocromil sodium and sodium cromoglycate inhaled shortly before exercise appear to reduce the severity of exercise-induced bronchoconstriction. There is some debate over which drug may be more effective. - Needle aspiration versus intercostal tube drainage for pneumothorax in the newborn
Cochrane Systematic Reviews, 31-Jan-2019
Pneumothorax occurs more frequently in the neonatal period than at any other time of life and is associated with increased mortality and morbidity. It can be treated with either aspiration with a syringe (using a needle or an angiocatheter) or a chest tub - Needle syringe programmes and opioid substitution therapy for preventing hepatitis C transmission in people who inject drugs
Cochrane Systematic Reviews, 14-Sep-2017
Needle syringe programmes and opioid substitution therapy for preventing hepatitis C transmission in people who inject drugs - Negative pressure wound therapy for open traumatic wounds
Cochrane Systematic Reviews, 3-Jul-2018
Traumatic wounds (wounds caused by injury) range from abrasions and minor skin incisions or tears, to wounds with extensive tissue damage or loss as well as damage to bone and internal organs. Two key types of traumatic wounds considered in this review ar - Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus
Cochrane Systematic Reviews, 16-Oct-2018
Foot wounds in people with diabetes mellitus (DM) are a common and serious global health issue. People with DM are prone to developing foot ulcers and, if these do not heal, they may also undergo foot amputation surgery resulting in postoperative wounds. - Negative pressure wound therapy for treating leg ulcers
Cochrane Systematic Reviews, 2-Dec-2016
Leg ulcers are open skin wounds that occur between the ankle and the knee that can last weeks, months or even years and are a consequence of arterial or venous valvular insufficiency. Negative pressure wound therapy (NPWT) is a technology that is currentl - Negative pressure wound therapy for treating pressure ulcers
Cochrane Systematic Reviews, 2-Jun-2015
Pressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. Negative pressure wound therapy (NPWT) is a treatment option for pressure ulcers; a clear, curren - Negative pressure wound therapy for treating surgical wounds healing by secondary intention
Cochrane Systematic Reviews, 29-May-2015
Following surgery, incisions are usually closed by fixing the edges together with sutures (stitches), staples, adhesive glue or clips. This process helps the cut edges heal together and is called 'healing by primary intention'. However, not all incised wo - Neo-adjuvant and adjuvant hormone therapy for localised and locally advanced prostate cancer
Cochrane Systematic Reviews, 3-Jun-2009
Hormone therapy for early prostate cancer has demonstrated an improvement in clinical and pathological variables, but not always an improvement in overall survival. We performed a systematic review of both adjuvant and neo-adjuvant hormone therapy combine - Neo-adjuvant chemotherapy for invasive bladder cancer
Cochrane Systematic Reviews, 17-Jan-2012
Controversy exists as to whether neoadjuvant chemotherapy improves survival in patients with invasive bladder cancer, despite randomised controlled trials (RCTs) involving over 3000 patients. - Neoadjuvant chemotherapy for locally advanced cervix cancer
Cochrane Systematic Reviews, 11-Feb-2015
The impact of neoadjuvant chemotherapy in the treatment of locally advanced cervical cancer remains uncertain. - Neoadjuvant chemotherapy versus none for resectable gastric cancer
Cochrane Systematic Reviews, 29-Oct-2008
Gastric cancer is a major cause of cancer death, and many patients are only diagnosed when the cancer has reached an advanced stage. Neoadjuvant chemotherapy (NAC), that is, chemotherapy administered shortly before surgical treatment, could provide a meth
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