- Prostaglandins for prelabour rupture of membranes at or near term
Cochrane Systematic Reviews, 6-Nov-2008
Induction of labour after prelabour rupture of membranes may reduce the risk of neonatal infection. However an expectant approach may be less likely to result in caesarean section. - Prostaglandins for preventing postpartum haemorrhage
Cochrane Systematic Reviews, 15-Aug-2012
Prostaglandins have mainly been used for postpartum haemorrhage (PPH) when other measures fail. Misoprostol, a new and inexpensive prostaglandin E1 analogue, has been suggested as an alternative for routine management of the third stage of labour. - Prostaglandins versus oxytocin for prelabour rupture of membranes at or near term
Cochrane Systematic Reviews, 6-Nov-2008
The conventional method of induction of labour is with intravenous oxytocin. More recently, induction with prostaglandins, followed by an infusion of oxytocin if necessary, has been used. - Prostaglandins versus oxytocin for prelabour rupture of membranes at term
Cochrane Systematic Reviews, 6-Nov-2008
The conventional method of induction of labour is with intravenous oxytocin. More recently, induction with prostaglandins, followed by an infusion of oxytocin if necessary, has been used. - Prostanoids and their analogues for the treatment of pulmonary hypertension in neonates
Cochrane Systematic Reviews, 1-Oct-2019
Persistent pulmonary hypertension of the newborn (PPHN) is a disease entity that describes a physiology in which there is persistence of increased pulmonary arterial pressure. PPHN is characterised by failure to adapt to a functional postnatal circulation - Prostanoids for critical limb ischaemia
Cochrane Systematic Reviews, 10-Jan-2018
Peripheral arterial occlusive disease (PAOD) is a common cause of morbidity and mortality due to cardiovascular disease in the general population. Although numerous treatments have been adopted for patients at different disease stages, no option other tha - Prostanoids for intermittent claudication
Cochrane Systematic Reviews, 14-Mar-2013
Peripheral arterial disease (PAD) is a common cause of morbidity in the general population. While numerous studies have established the efficacy of prostanoids in PAD stages III and IV, the question of the role of prostanoids as an alternative or additive - Prostate MRI, with or without MRI‐targeted biopsy, and systematic biopsy for detecting prostate cancer
Cochrane Systematic Reviews, 25-Apr-2019
Multiparametric magnetic resonance imaging (MRI), with or without MRI-targeted biopsy, is an alternative test to systematic transrectal ultrasonography-guided biopsy in men suspected of having prostate cancer. At present, evidence on which test to use is - Prostatic arterial embolization for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia
Cochrane Systematic Reviews, 29-Mar-2022
A variety of minimally invasive surgical approaches are available as an alternative to transurethral resection of the prostate (TURP) for management of lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH). Prostatic arterial - Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia
Cochrane Systematic Reviews, 23-May-2019
A variety of minimally invasive surgical approaches are available as an alternative to transurethral resection of prostate (TURP) for the management of lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH). A recent addition t - Prosthetic mesh placement for the prevention of parastomal herniation
Cochrane Systematic Reviews, 20-Jul-2018
Parastomal herniation is a common problem following formation of a stoma after both elective and emergency abdominal surgery. Symptomatic hernias give rise to a significant amount of patient morbidity, and in some cases mortality, and therefore may necess - Prosthetic rehabilitation for older dysvascular people following a unilateral transfemoral amputation
Cochrane Systematic Reviews, 23-Oct-2018
Dysvascularity accounts for 75% of all lower limb amputations in the UK. Around 37% of these procedures are done at the transfemoral level (mid-thigh), with most patients over the age of 60 and having existing comorbidities. A significant number of these - Protease activity as a prognostic factor for wound healing in venous leg ulcers
Cochrane Systematic Reviews, 1-Sep-2018
Venous leg ulcers (VLUs) are a common type of complex wound that have a negative impact on people's lives and incur high costs for health services and society. It has been suggested that prolonged high levels of protease activity in the later stages of th - Protease‐modulating matrix treatments for healing venous leg ulcers
Cochrane Systematic Reviews, 15-Dec-2016
Venous leg ulcers (VLUs) are open skin wounds on the lower leg that occur because of poor blood flow in the veins of the leg; leg ulcers can last from weeks to years, and are both painful and costly. Prevalence in the UK is about 2.9 cases per 10,000 peop - Protein and energy supplementation in elderly people at risk from malnutrition
Cochrane Systematic Reviews, 15-Apr-2009
Evidence for the effectiveness of nutritional supplements containing protein and energy, often prescribed for older people, is limited. Malnutrition is more common in this age group and deterioration of nutritional status can occur during illness. It is i - Protein containing synthetic surfactant versus animal derived surfactant extract for the prevention and treatment of respiratory distress syndrome
Cochrane Systematic Reviews, 23-Sep-2008
Respiratory distress syndrome (RDS) is a significant cause of morbidity and mortality in preterm infants. RDS is caused by a deficiency, dysfunction, or inactivation of pulmonary surfactant. Numerous surfactants of either animal extract or synthetic desig - Protein hydrolysate versus standard formula for preterm infants
Cochrane Systematic Reviews, 24-Jul-2019
When human milk is not available for feeding preterm infants, protein hydrolysate, rather than standard cow's milk formulas (with intact proteins), is often used because it is perceived as being tolerated better and less likely to lead to complications. H - Protein restriction for children with chronic kidney disease
Cochrane Systematic Reviews, 17-Oct-2007
Protein restriction has been prescribed for some time for patients with chronic kidney disease (CKD). The effect of a low protein diet on delaying the progression to end-stage kidney disease (ESKD) in children and its impact on growth and nutrition remain - Protein restriction for diabetic renal disease
Cochrane Systematic Reviews, 17-Oct-2007
Diabetic renal disease (diabetic nephropathy) is a leading cause of end-stage renal failure. Once the process has started, it cannot be reversed by glycaemic control, but progression might be slowed by control of blood pressure and protein restriction. - Protein substitute for children and adults with phenylketonuria
Cochrane Systematic Reviews, 27-Feb-2015
Phenylketonuria is an inherited metabolic disorder characterised by an absence or deficiency of the enzyme phenylalanine hydroxylase. The aim of treatment is to lower blood phenylalanine concentrations to the recommended therapeutic range to prevent devel
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