- Laser-assisted subepithelial keratectomy (LASEK) versus laser-assisted in-situ keratomileusis (LASIK) for correcting myopia
Cochrane Systematic Reviews, 10-Feb-2017
Near-sightedness, or myopia, is a condition in which light rays entering the eye along the visual axis focus in front of the retina, resulting in blurred vision. Myopia can be treated with spectacles, contact lenses, or refractive surgery. Options for ref - Laser-assisted subepithelial keratectomy (LASEK) versus photorefractive keratectomy (PRK) for correction of myopia
Cochrane Systematic Reviews, 19-Feb-2016
Myopia (near-sightedness or short-sightedness) is a condition in which the refractive power of the eye is greater than required. The most frequent complaint of people with myopia is blurred distance vision, which can be eliminated by conventional optical - Lasers for caries removal in deciduous and permanent teeth
Cochrane Systematic Reviews, 25-Sep-2016
Despite considerable improvements in oral health, dental caries continue to be a public health issue. The most frequently used, and universally accepted technique, to remove caries is through mechanical ablation of decayed tissues by means of rotating dri - Lasers or light sources for treating port-wine stains
Cochrane Systematic Reviews, 26-Sep-2011
Port-wine stains are birthmarks caused by malformations of blood vessels in the skin. Port-wine stains manifest themselves in infancy as a flat, red mark and do not regress spontaneously but may, if untreated, become darker and thicker in adult life. The - Late versus early surgical correction for congenital diaphragmatic hernia in newborn infants
Cochrane Systematic Reviews, 13-Apr-2010
Congenital diaphragmatic hernia, although rare (1 per 2-4,000 births), is associated with high mortality and cost. Opinion regarding the timing of surgical repair has gradually shifted from emergent repair to a policy of stabilization using a variety of v - Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV
Cochrane Systematic Reviews, 17-Oct-2019
The lateral flow urine lipoarabinomannan (LF-LAM) assay Alere Determine™ TB LAM Ag is recommended by the World Health Organization (WHO) to help detect active tuberculosis in HIV-positive people with severe HIV disease. This review update asks the questio - Lateral tilt for caesarean section
Cochrane Systematic Reviews, 10-May-2010
When pregnant women near term lie in the supine position the uterus can compress the inferior vena cava, interfering with venous return to the heart. This can result in hypotension, reduced placental perfusion and decreased fetal oxygenation. - Latrepirdine for Alzheimer's disease
Cochrane Systematic Reviews, 21-Apr-2015
Current treatments for Alzheimer’s disease (AD) provide modest symptomatic relief but do not slow the progression of the disease. Latrepirdine may modulate several targets involved in AD pathology, including lipid peroxidation, mitochondrial permeability, - Laxatives for the treatment of hemorrhoids.
Cochrane Systematic Reviews, 4-Aug-2008
Symptomatic hemorrhoids are a common medical condition, which increase in prevalence in women during pregnancy and postpartum. Although the evidence appears to be inconclusive, narrative reviews and clinical practice guidelines recommend the use of laxati - Lay-led and peer support interventions for adolescents with asthma
Cochrane Systematic Reviews, 19-Apr-2017
Adolescents with asthma are at high risk of poor adherence with treatment. This may be compounded by activities that worsen asthma, in particular smoking. Additional support above and beyond routine care has the potential to encourage good self-management - Leflunomide for the treatment of rheumatoid arthritis
Cochrane Systematic Reviews, 16-Jun-2010
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease. Leflunomide is one of the more recent oral agents, classified as a disease-modifying antirheumatic drug (DMARD). It has a different mechanism of action than other existing DMARDs. - Legislative smoking bans for reducing harms from secondhand smoke exposure, smoking prevalence and tobacco consumption
Cochrane Systematic Reviews, 4-Feb-2016
Smoking bans have been implemented in a variety of settings, as well as being part of policy in many jurisdictions to protect the public and employees from the harmful effects of secondhand smoke (SHS). They also offer the potential to influence social no - Lens extraction for chronic angle-closure glaucoma
Cochrane Systematic Reviews, 17-Oct-2008
Angle-closure glaucoma is characterized by obstruction to the outflow of aqueous humor and consequent rise in intraocular pressure. The obstruction may result from an anatomical predisposition of the eye or may be due to pathophysiologic processes in any - Leukodepletion for patients undergoing heart valve surgery
Cochrane Systematic Reviews, 29-Jul-2013
There is some evidence for the benefits of leukodepletion in patients undergoing coronary artery surgery. Its effectiveness in higher risk patients, such as those undergoing heart valve surgery, particularly in terms of overall clinical outcomes, is curre - Leukoreduction for the prevention of adverse reactions from allogeneic blood transfusion
Cochrane Systematic Reviews, 2-Dec-2015
A blood transfusion is an acute intervention, implemented to solve life and health-threatening conditions on a short-term basis. However, blood transfusions have adverse events, some of them potentially related to immune modulation or to a direct transmis - Leukotriene receptor antagonist for prolonged non-specific cough in children
Cochrane Systematic Reviews, 14-Nov-2010
Non-specific cough is defined as non-productive cough in the absence of identifiable respiratory disease or known aetiology. It is commonly seen in paediatric practice. These children are treated with a variety of therapies including a variety of asthma m - Leukotriene receptor antagonists for eczema
Cochrane Systematic Reviews, 11-Oct-2018
Eczema is a common, chronic, inflammatory skin condition that is frequently associated with atopic conditions, including asthma. Leukotriene receptor antagonists (LTRAs) have a corticosteroid-sparing role in asthma, but their role in eczema remains contro - Leukotriene receptor antagonists for non-cystic fibrosis bronchiectasis
Cochrane Systematic Reviews, 1-Jun-2011
Leukotriene receptor antagonists are a new class of drug that were initially identified for use in asthma. As they have an effect on neutrophil mediated inflammation, they may be of benefit in bronchiectasis. - Leukotriene receptor antagonists in addition to usual care for acute asthma in adults and children
Cochrane Systematic Reviews, 2-Apr-2012
Acute asthma presentation in the emergency setting frequently leads to hospital admission. Currently available treatment options include corticosteroid therapy, beta2-agonists and oxygen. Antileukotriene agents are beneficial in chronic asthma as addition - Levetiracetam for neuropathic pain in adults
Cochrane Systematic Reviews, 29-May-2019
Antiepileptic drugs have been used in pain management since the 1960s; some have shown efficacy in treating different neuropathic pain conditions. The efficacy of levetiracetam for relief of neuropathic pain has not previously been reviewed.
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