- Radical radiotherapy for stage I/II non-small cell lung cancer in patients not sufficiently fit for or declining surgery (medically inoperable)
Cochrane Systematic Reviews, 9-Mar-2015
In general, surgery is believed to offer the best prospects for cure for early stage non-small cell lung cancer (NSCLC). In spite of the intention to consider all patients with stage I-II disease for surgery, there are those who, although technically oper - Radiofrequency (thermal) ablation versus no intervention or other interventions for hepatocellular carcinoma
Cochrane Systematic Reviews, 18-Dec-2013
Hepatocellular carcinoma is the fifth most common cancer worldwide. Percutaneous interventional therapies, such as radiofrequency (thermal) ablation (RFA), have been developed for early hepatocellular carcinoma. RFA competes with other interventional tech - Radiofrequency ablation in the treatment of liver metastases from colorectal cancer
Cochrane Systematic Reviews, 9-May-2012
Colorectal cancer (CRC) is the most common malignant tumour and the third leading cause of cancer deaths in USA. For advanced CRC, the liver is the first site of metastatic disease; approximately 50 % of patients with CRC will develop liver metastases eit - Radiofrequency denervation for chronic low back pain
Cochrane Systematic Reviews, 14-Oct-2015
Radiofrequency (RF) denervation, an invasive treatment for chronic low back pain (CLBP), is used most often for pain suspected to arise from facet joints, sacroiliac (SI) joints or discs. Many (uncontrolled) studies have shown substantial variation in its - Radiofrequency denervation for neck and back pain
Cochrane Systematic Reviews, 16-Feb-2010
The diagnosis of cervical or lumbar zygapophyseal joint pain can only be made by using local anaesthesia to block the nerves supplying the painful joint. There is a lack of effective treatment for chronic zygapophyseal joint pain or discogenic pain. Radio - Radioiodine therapy for differentiated thyroid carcinoma with thyroglobulin positive and radioactive iodine negative metastases
Cochrane Systematic Reviews, 10-Nov-2008
Differentiated thyroid carcinoma with thyroglobulin positive and radioactive iodine negative metastases has been observed in follow-up studies. The management of this condition remains controversial. Most studies support blind radioactive iodine treatment - Radioiodine therapy versus antithyroid medications for Graves' disease
Cochrane Systematic Reviews, 18-Jan-2016
Graves' disease is the most common cause of hyperthyroidism. Both antithyroid medications and radioiodine are commonly used treatments but their frequency of use varies between regions and countries. Despite the commonness of the diagnosis, any possible d - Radioiodine treatment for pediatric Graves' disease
Cochrane Systematic Reviews, 27-Oct-2008
Pediatric Graves' disease (GD) is an autoimmune disease in which excessive amounts of thyroid hormones circulate in the blood. Treatments for pediatric GD include antithyroid drugs (ATD), thyroidectomy and radioiodine. Up to date, the optimal therapy rema - Radioisotopes for metastatic bone pain
Cochrane Systematic Reviews, 23-Mar-2017
This is an update of the review published in Issue 4, 2003. Bone metastasis cause severe pain as well as pathological fractures, hypercalcaemia and spinal cord compression. Treatment strategies currently available to relieve pain from bone metastases incl - Radiotherapy and chemoradiation after surgery for early cervical cancer
Cochrane Systematic Reviews, 18-Apr-2012
This is an updated version of the original Cochrane review first published in Issue 4, 2009. There is an ongoing debate about the indications for, and value of, adjuvant pelvic radiotherapy after radical surgery in women with early cervical cancer. Certai - Radiotherapy for diffuse brainstem glioma in children and young adults
Cochrane Systematic Reviews, 26-May-2016
Diffuse brainstem glioma is a devastating disease with very poor prognosis. The most commonly used radiological treatment is conventional fractionated radiation. So far, there is no meta-analysis or systematic review available that assesses the benefits o - Radiotherapy for early breast cancer
Cochrane Systematic Reviews, 5-Aug-2008
The long-term effects of radiotherapy on mortality from breast cancer and other causes remain uncertain. - Radiotherapy for malignant pleural mesothelioma
Cochrane Systematic Reviews, 14-Mar-2010
Malignant pleural mesothelioma is a relatively uncommon disease, but the incidence is increasing and is expected to peak in many developed countries in the next two decades. The management of patients with malignant mesothelioma is controversial. Very few - Radiotherapy for neovascular age-related macular degeneration
Cochrane Systematic Reviews, 13-Apr-2010
Radiotherapy has been proposed as a treatment to prevent new vessel growth in people with neovascular age-related macular degeneration (AMD). - Radiotherapy for the palliation of painful bone metastases
Cochrane Systematic Reviews, 10-Jun-2019
Radiotherapy is used commonly to provide pain relief for painful bone metastases, and there is a perception that of the three-quarters of patients who achieve pain relief, half of these stay free from pain. However, the precise contribution from radiother - Radiotherapy versus open surgery versus endolaryngeal surgery (with or without laser) for early laryngeal squamous cell cancer
Cochrane Systematic Reviews, 19-Nov-2014
This is an update of a Cochrane review first published in The Cochrane Library in Issue 2, 2002 and previously updated in 2004, 2007 and 2010. - Radix Sophorae flavescentis versus no intervention or placebo for chronic hepatitis B
Cochrane Systematic Reviews, 2-Apr-2019
Hepatitis B virus (HBV) infection, a liver disease caused by hepatitis B virus, may lead to serious complications such as cirrhosis and hepatocellular carcinoma. People with HBV infection may have co-infections including HIV and other hepatitis viruses (h - Radix Sophorae flavescentis versus other drugs or herbs for chronic hepatitis B
Cochrane Systematic Reviews, 19-Jun-2019
Hepatitis B virus (HBV) infection is a liver disease caused by hepatitis B virus, which may lead to serious complications such as cirrhosis and hepatocellular carcinoma. People with HBV infection may also have coinfections including HIV and other hepatiti - Ranolazine for stable angina pectoris
Cochrane Systematic Reviews, 24-Jan-2019
Stable angina pectoris is a chronic medical condition with significant impact on mortality and quality of life; it can be macrovascular or microvascular in origin. Ranolazine is a second-line anti-anginal drug approved for use in people with stable angina - Rapamycin and rapalogs for tuberous sclerosis complex
Cochrane Systematic Reviews, 29-Jun-2017
Previous studies have shown potential benefits of rapamycin or rapalogs for treating people with tuberous sclerosis complex. Although everolimus (a rapalog) is currently approved by the FDA (U.S. Food and Drug Administration) and the EMA (European Medicin
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