- Antidepressants for the treatment of depression in people with cancer
Cochrane Systematic Reviews, 3-Apr-2018
Major depression and other depressive conditions are common in people with cancer. These conditions are not easily detectable in clinical practice, due to the overlap between medical and psychiatric symptoms, as described by diagnostic manuals such as the - Antidepressants for the treatment of people with co‐occurring depression and alcohol dependence
Cochrane Systematic Reviews, 22-Apr-2018
Alcohol dependence is a major public health problem characterized by recidivism, and medical and psychosocial complications. The co-occurrence of major depression in people entering treatment for alcohol dependence is common, and represents a risk factor - Antidepressants for treating depression in adults with end-stage kidney disease treated with dialysis
Cochrane Systematic Reviews, 18-Apr-2016
Depression affects approximately one-quarter of people treated with dialysis and is considered an important research uncertainty by patients and health professionals. Treatment for depression in dialysis patients may have different benefits and harms comp - Antidepressants for treating depression in dementia
Cochrane Systematic Reviews, 30-Aug-2018
The use of antidepressants in dementia accompanied by depressive symptoms is widespread, but their clinical efficacy is uncertain. This review updates an earlier version, first published in 2002. - Antidepressants plus benzodiazepines for adults with major depression
Cochrane Systematic Reviews, 3-Jun-2019
Anxiety frequently coexists with depression and adding benzodiazepines to antidepressant treatment is common practice to treat people with major depression. However, more evidence is needed to determine whether this combined treatment is more effective an - Antidepressants versus placebo for depression in primary care
Cochrane Systematic Reviews, 11-Apr-2014
Concern has been expressed about the relevance of secondary care studies to primary care patients specifically about the effectiveness of antidepressant medication. There is a need to review the evidence of only those studies that have been conducted comp - Antidepressants versus placebo for panic disorder in adults
Cochrane Systematic Reviews, 3-Apr-2018
Panic disorder is characterised by repeated, unexpected panic attacks, which represent a discrete period of fear or anxiety that has a rapid onset, reaches a peak within 10 minutes, and in which at least four of 13 characteristic symptoms are experienced, - Antidepressants versus placebo for people with bulimia nervosa
Cochrane Systematic Reviews, 31-Oct-2008
Bulimia Nervosa (BN) represents an important public health problem and is related to serious morbidity and even mortality. This review attempted to systematically evaluate the use of antidepressant medications compared with placebo for the treatment of bu - Antidepressants versus placebo for the depressed elderly
Cochrane Systematic Reviews, 31-Oct-2008
Depression warranting intervention is found in ten percent of people over the age of 60. Older depressed people are more likely to die than non-depressed. Relatively few receive therapeutic interventions, and those that do, tend to receive low dose antide - Antidepressants versus psychological treatments and their combination for bulimia nervosa
Cochrane Systematic Reviews, 24-Feb-2010
Psychotherapeutic approaches, mainly cognitive behavior therapy, and antidepressant medication are the two treatment modalities that have received most support in controlled outcome studies of bulimia nervosa. - Antidotes for acute cardenolide (cardiac glycoside) poisoning
Cochrane Systematic Reviews, 12-Oct-2008
Cardenolides are naturally occurring plant toxins which act primarily on the heart. While poisoning with the digitalis cardenolides (digoxin and digitoxin) are reported worldwide, cardiotoxicity from other cardenolides such as the yellow oleander are also - Antiemetic medication for prevention and treatment of chemotherapy‐induced nausea and vomiting in childhood
Cochrane Systematic Reviews, 22-Dec-2015
Nausea and vomiting remain a problem for children undergoing treatment for malignancies despite new antiemetic therapies. Optimising antiemetic regimens could improve quality of life by reducing nausea, vomiting, and associated clinical problems. This is - Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents
Cochrane Systematic Reviews, 7-Aug-2011
Vomiting is a common manifestation of acute gastroenteritis in children and adolescents. When untreated it can be a hindrance to oral rehydration therapy, which is the cornerstone in the management of acute gastroenteritis. Evidence is needed concerning t - Anti‐epidermal growth factor receptor therapy for glioblastoma in adults
Cochrane Systematic Reviews,
Glioblastoma is an uncommon but highly aggressive type of brain tumour. Significant gains have been achieved in the molecular understanding and the pathogenesis of glioblastomas, however clinical improvements are difficult to obtain for many reasons. The - Antiepileptic drug monotherapy for epilepsy: a network meta‐analysis of individual participant data
Cochrane Systematic Reviews, 14-Dec-2017
Epilepsy is a common neurological condition with a worldwide prevalence of around 1%. Approximately 60% to 70% of people with epilepsy will achieve a longer-term remission from seizures, and most achieve that remission shortly after starting antiepileptic - Antiepileptic drugs as prophylaxis for postcraniotomy seizures
Cochrane Systematic Reviews,
This is an updated version of the Cochrane Review previously published in 2018. - Antiepileptic drugs for chronic non‐cancer pain in children and adolescents
Cochrane Systematic Reviews, 25-Feb-2020
Pain is a common feature of childhood and adolescence around the world, and for many young people, that pain is chronic. The World Health Organization (WHO) guidelines for pharmacological treatments for children's persisting pain acknowledge that pain in - Antiepileptic drugs for neuropathic pain and fibromyalgia - an overview of Cochrane reviews
Cochrane Systematic Reviews, 28-May-2019
Antiepileptic drugs have been used for treating different types of neuropathic pain, and sometimes fibromyalgia. Our understanding of quality standards in chronic pain trials has improved to include new sources of potential bias. Individual Cochrane revie - Antiepileptic drugs for preventing seizures following acute traumatic brain injury
Cochrane Systematic Reviews, 16-May-2012
Seizure activity in the early post-traumatic period following head injury may cause secondary brain damage as a result of increased metabolic demands, raised intracranial pressure and excess neurotransmitter release. - Antiepileptic drugs for preventing seizures in people with brain tumors
Cochrane Systematic Reviews, 19-Oct-2008
Seizures can present at any time before or after diagnosis of a brain tumor. The risk of seizures varies by tumor type and its location in the brain. For a long time we believed that preventing seizures with antiepileptic drugs (seizure prophylaxis) was e
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