- Antihypertensive treatment for kidney transplant recipients
Cochrane Systematic Reviews, 29-Nov-2009
In some nontransplant populations, effects of different antihypertensive drug classes vary. Relative effects in kidney transplant recipients are uncertain. - Antihypertensive withdrawal for the prevention of cognitive decline
Cochrane Systematic Reviews, 1-Nov-2016
Clinical trials and observational data have variously shown a protective, harmful or neutral effect of antihypertensives on cognitive function. In theory, withdrawal of antihypertensives could improve cerebral perfusion and reduce or delay cognitive decli - Anti-IgE therapy for allergic bronchopulmonary aspergillosis in people with cystic fibrosis
Cochrane Systematic Reviews, 13-Mar-2018
Cystic fibrosis is an autosomal recessive multisystem disorder with an approximate prevalence of 1 in 3500 live births. Allergic bronchopulmonary aspergillosis is a lung disease caused by aspergillus-induced hypersensitivity with a prevalence of 2% to 15% - Anti-IL-12/23p40 antibodies for induction of remission in Crohn's disease
Cochrane Systematic Reviews, 24-Nov-2016
Ustekinumab (CNTO 1275) and briakinumab (ABT-874) are monoclonal antibodies that target the standard p40 subunit of the cytokines interleukin-12 and interleukin-23 (IL-12/23p40), which are involved in the pathogenesis of Crohn's disease. - Anti-IL5 therapies for asthma
Cochrane Systematic Reviews, 21-Sep-2017
This review is the first update of a previously published review in The Cochrane Library (Issue 7, 2015). Interleukin-5 (IL-5) is the main cytokine involved in the activation of eosinophils, which cause airway inflammation and are a classic feature of ast - Anti-inflammatory drugs and analgesics for managing symptoms in people with cystic fibrosis-related arthritis
Cochrane Systematic Reviews, 21-Jan-2016
Arthritis remains a relatively infrequent complication of cystic fibrosis, but is a cause of significant morbidity when it does occur. Two distinct types of arthritis are described in cystic fibrosis: cystic fibrosis-related arthropathy (CFA) and hypertro - Anti-inflammatory treatment for carditis in acute rheumatic fever
Cochrane Systematic Reviews, 14-Apr-2016
Rheumatic heart disease remains an important cause of acquired heart disease in developing countries. Although prevention of rheumatic fever and management of recurrences have been well established, optimal management of active rheumatic carditis remains - Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children
Cochrane Systematic Reviews, 8-Dec-2014
Anti-leukotrienes (5-lipoxygenase inhibitors and leukotriene receptors antagonists) serve as alternative monotherapy to inhaled corticosteroids (ICS) in the management of recurrent and/or chronic asthma in adults and children. - Antimalarials for treating rheumatoid arthritis
Cochrane Systematic Reviews, 24-May-2010
Antimalarials have been used for the treatment of rheumatoid arthritis (RA) for several decades. Recently several trials have been published with larger sample sizes, and better design than previous studies. These newer trials have evaluated the efficacy - Antimetabolites in cataract surgery to prevent failure of a previous trabeculectomy
Cochrane Systematic Reviews, 20-Jul-2014
Patients having cataract surgery have often earlier undergone a trabeculectomy for glaucoma. However, cataract surgery may be associated with failure of the previous glaucoma surgery and antimetabolites may be used with cataract surgery to prevent such fa - Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients
Cochrane Systematic Reviews, 8-Jun-2017
Peritoneal dialysis (PD) is an important therapy for patients with end-stage kidney disease and is used in more than 200,000 such patients globally. However, its value is often limited by the development of infections such as peritonitis and exit-site and - Antimicrobial agents for treating uncomplicated urinary tract infection in women
Cochrane Systematic Reviews, 8-Nov-2010
Acute uncomplicated lower urinary tract infection (UTI) is one of the most common problems for which young women seek medical attention. - Antimicrobial dressings for the prevention of catheter-related infections in newborn infants with central venous catheters
Cochrane Systematic Reviews, 25-Jan-2017
Central venous catheters (CVCs) provide secured venous access in neonates. Antimicrobial dressings applied over the CVC sites have been proposed to reduce catheter-related blood stream infection (CRBSI) by decreasing colonisation. However, there may be co - Antimicrobial drugs for treating cholera
Cochrane Systematic Reviews, 12-Jun-2014
Cholera is an acute watery diarrhoea caused by infection with the bacterium Vibrio cholerae, which if severe can cause rapid dehydration and death. Effective management requires early diagnosis and rehydration using oral rehydration salts or intravenous f - Antimicrobial drugs for treating methicillin-resistant Staphylococcus aureus colonization
Cochrane Systematic Reviews, 17-Jun-2008
Eradication strategies for methicillin-resistant Staphylococcus aureus (MRSA) are variable. We sought to summarize the evidence for use of antimicrobial agents to eradicate MRSA. - Antimicrobial lock solutions for preventing catheter-related infections in haemodialysis
Cochrane Systematic Reviews, 30-Mar-2018
Patients undergoing haemodialysis (HD) through a central venous catheter (CVC) are exposed to several risks, being a catheter-related infection (CRI) and a CVC lumen thrombosis among the most serious. Standard of care regarding CVCs includes their sealing - Antimicrobial prophylaxis for colorectal surgery
Cochrane Systematic Reviews, 27-Aug-2015
Research shows that administration of prophylactic antibiotics before colorectal surgery prevents postoperative surgical wound infection. The best antibiotic choice, timing of administration and route of administration remain undetermined. - Antimicrobial therapy for chronic bacterial prostatitis
Cochrane Systematic Reviews, 2-Aug-2013
Chronic bacterial prostatitis (CBP) is frequently diagnosed in men of fertile age, and is characterized by a disabling array of symptoms, including pain in the pelvic area (for example, perineum, testicles), voiding symptoms (increased frequency and urgen - Antimicrobial-impregnated central venous catheters for prevention of catheter-related bloodstream infection in newborn infants
Cochrane Systematic Reviews, 24-Sep-2015
Central venous catheter-related bloodstream infection is an important cause of mortality and morbidity in newborn infants cared for in neonatal units. Potential strategies to prevent these infections include the use of central venous catheters impregnated - Antimicrobials for treating symptomatic non-typhoidal Salmonella infection
Cochrane Systematic Reviews, 12-Oct-2012
Non-typhoidal Salmonella (NTS) commonly causes diarrhoea, and is usually self-limiting, although sometimes people become ill with sepsis and dehydration. Routine antibiotic use for this infection could result in persistent colonization and the spread of r
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