- Intratracheal Clara cell secretory protein (CCSP) administration in preterm infants with or at risk of respiratory distress syndrome
Cochrane Systematic Reviews, 6-Mar-2017
Clara cell secretory protein (CCSP) is an immune-modulating and anti-inflammatory agent. CCSP is available synthetically as recombinant human Clara cell protein (rhCC10). It has been shown in animal models to reduce lung injury, improve pulmonary complian - Intratympanic gentamicin for Ménière's disease or syndrome
Cochrane Systematic Reviews, 6-Mar-2011
Ménière's disease is characterised by three major symptoms: vertigo, deafness and tinnitus, which may be accompanied by aural fullness, all of which are discontinuous and variable in intensity. While discontinuous, these symptoms are synchronous. Intratym - Intratympanic steroids for Ménière's disease or syndrome
Cochrane Systematic Reviews, 13-Jun-2011
Ménière's disease is a disorder characterised by hearing loss, tinnitus and disabling vertigo. The use of intratympanic steroids to reduce the severity of these symptoms has been gaining popularity. - Intrauterine insemination versus fallopian tube sperm perfusion for non-tubal infertility
Cochrane Systematic Reviews, 30-Oct-2013
Intrauterine insemination (IUI) is a common treatment for couples with subfertility that does not involve the fallopian tubes. It is used to bring the sperm close to the released oocyte. Another method of introducing sperm is fallopian tube sperm perfusio - Intra-uterine insemination versus timed intercourse or expectant management for cervical hostility in subfertile couples
Cochrane Systematic Reviews, 20-Sep-2010
The postcoital test has poor diagnostic and prognostic characteristics. Nevertheless, some physicians believe it can identify scanty or abnormal mucus that might impair fertility. One way to avoid 'hostile' cervical mucus is intrauterine insemination. Wit - Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease
Cochrane Systematic Reviews, 9-Sep-2016
Alpha-1 antitrypsin deficiency is an inherited disorder that can cause chronic obstructive pulmonary disease (COPD). People who smoke are more seriously affected and have a greater risk of dying from the disease. Therefore, the primary treatment is to hel - Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis
Cochrane Systematic Reviews, 29-Jun-2017
Cystic fibrosis is a multi-system disease characterised by the production of thick secretions causing recurrent pulmonary infection, often with unusual bacteria. Intravenous antibiotics are commonly used in the treatment of acute deteriorations in symptom - Intravenous beta2-agonists for acute asthma in the emergency department
Cochrane Systematic Reviews, 10-Feb-2012
Inhaled beta-agonist therapy is central to the management of acute asthma. The use of intravenous beta-agonist agents may also be beneficial in this setting. - Intravenous beta2-agonists versus intravenous aminophylline for acute asthma
Cochrane Systematic Reviews, 13-Nov-2012
Inhaled beta2-agonist therapy is central to the management of acute asthma. For rapid bronchodilation in severe cases, penetration of inhaled drug to the affected small conducting airway may be impeded, and the intravenous (IV) rather than inhaled adminis - Intravenous fluids for reducing the duration of labour in low risk nulliparous women
Cochrane Systematic Reviews, 18-Jun-2013
Several factors may influence the progression of normal labour. It has been postulated that the routine administration of intravenous fluids to keep women adequately hydrated during labour may reduce the period of contraction and relaxation of the uterine - Intravenous heparin during ruptured abdominal aortic aneurysmal repair
Cochrane Systematic Reviews, 11-Aug-2016
There have been enormous advances in the screening, diagnosis, intervention and overall prognosis of abdominal aortic aneurysms (AAAs) in the last decade, but despite these, ruptured AAAs (rAAAs) still cause around 3500 to 6000 deaths in England and Wales - Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy
Cochrane Systematic Reviews, 20-Dec-2013
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) causes progressive or relapsing weakness and numbness of the limbs, developing over at least two months. Uncontrolled studies suggest that intravenous immunoglobulin (IVIg) helps. This revie - Intravenous immunoglobulin for multifocal motor neuropathy
Cochrane Systematic Reviews, 3-Nov-2008
Multifocal motor neuropathy is a rare, probably immune mediated disorder characterised by slowly progressive, asymmetric, distal weakness of one or more limbs with no objective loss of sensation. It may cause prolonged periods of disability. The treatment - Intravenous immunoglobulin for the treatment of childhood encephalitis
Cochrane Systematic Reviews, 28-Sep-2017
Encephalitis is a syndrome of neurological dysfunction due to inflammation of the brain parenchyma, caused by an infection or an exaggerated host immune response, or both. Attenuation of brain inflammation through modulation of the immune response could i - Intravenous immunoglobulins for multiple sclerosis
Cochrane Systematic Reviews, 19-Jan-2010
Animal experiments suggest that intravenous immunoglobulins can reverse some of the disease process of central nervous system demyelination. Subsequently, clinical trials of intravenous immunoglobulins have been conducted in people with multiple sclerosis - Intravenous magnesium for acute myocardial infarction
Cochrane Systematic Reviews, 30-Sep-2008
Mortality and morbidity from acute myocardial infarction (AMI) remain high. Intravenous magnesium started early after the onset of AMI is thought to be a promising adjuvant treatment. Conflicting results from earlier trials and meta-analyses warrant a sys - Intravenous magnesium sulfate for treating adults with acute asthma in the emergency department
Cochrane Systematic Reviews, 21-May-2014
Asthma is a chronic respiratory condition characterised by airways inflammation, constriction of airway smooth muscle and structural alteration of the airways that is at least partially reversible. Exacerbations of asthma can be life threatening and place - Intravenous magnesium sulfate for treating children with acute asthma in the emergency department
Cochrane Systematic Reviews, 28-Apr-2016
Acute asthma in children can be life-threatening and must be treated promptly in the emergency setting. Intravenous magnesium sulfate is recommended by various guidelines for cases of acute asthma that have not responded to first-line treatment with bronc - Intravenous nutrients for preventing inadvertent perioperative hypothermia in adults
Cochrane Systematic Reviews, 21-Nov-2016
Inadvertent perioperative hypothermia (a drop in core temperature to below 36°C) occurs because normal temperature regulation is disrupted during surgery, mainly because of the effects of anaesthetic drugs and exposure of the skin for prolonged periods. M - Intravenous or intramuscular parecoxib for acute postoperative pain in adults
Cochrane Systematic Reviews, 29-May-2019
Parecoxib was the first COX-2 available for parenteral administration, and may, given intravenously or intramuscularly, offer advantages over oral medication when patients have nausea and vomiting or are unable to swallow, such as in the immediate postope
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