- Plasma volume expansion for suspected impaired fetal growth
Cochrane Systematic Reviews, 21-Oct-1996
Failure of the normal expansion of plasma volume in the mother is associated with impaired fetal growth and pre-eclampsia. - Plasma volume expansion for treatment of pre‐eclampsia
Cochrane Systematic Reviews, 25-Oct-1999
Plasma volume is reduced amongst women with pre-eclampsia. This association has led to the suggestion that expanding the plasma volume might improve maternal and uteroplacental circulation, and so potentially improve outcome for both the woman and her bab - Platelet count, spleen length, and platelet count‐to‐spleen length ratio for the diagnosis of oesophageal varices in people with chronic liver disease or portal vein thrombosis
Cochrane Systematic Reviews, 26-Apr-2017
Current guidelines recommend screening of people with oesophageal varices via oesophago-gastro-duodenoscopy at the time of diagnosis of hepatic cirrhosis. This requires that people repeatedly undergo unpleasant invasive procedures with their attendant ris - Platelet glycoprotein IIb/IIIa blockers during percutaneous coronary intervention and as the initial medical treatment of non-ST segment elevation acute coronary syndromes
Cochrane Systematic Reviews, 7-Nov-2013
During percutaneous coronary intervention (PCI), and in non-ST segment elevation acute coronary syndromes (NSTEACS), the risk of acute vessel occlusion by thrombosis is high. Glycoprotein IIb/IIIa blockers strongly inhibit platelet aggregation and may pre - Platelet rich therapies for long bone healing in adults
Cochrane Systematic Reviews, 25-May-2012
The morbidity and socioeconomic costs associated with long bone healing are considerable. Platelet-rich therapies are autologous blood products with a greater concentration of platelets than physiological whole blood. Despite promising results from a numb - Platelet-rich therapies for musculoskeletal soft tissue injuries
Cochrane Systematic Reviews, 28-Apr-2014
Platelet-rich therapies are being used increasingly in the treatment of musculoskeletal soft tissue injuries such as ligament, muscle and tendon tears and tendinopathies. These therapies can be used as the principal treatment or as an augmentation procedu - Platelet‐rich‐plasmapheresis for minimising peri‐operative allogeneic blood transfusion
Cochrane Systematic Reviews, 16-Mar-2011
Concerns regarding the safety of transfused blood have generated considerable enthusiasm for the use of technologies intended to reduce the use of allogeneic blood (blood from an unrelated donor). Platelet-rich plasmapheresis (PRP) offers an alternative a - Platinum versus non‐platinum chemotherapy regimens for small cell lung cancer
Cochrane Systematic Reviews, 2-Aug-2015
Small cell lung cancer (SCLC) is a very fast growing form of cancer and is characterised by early metastasis. As a result, chemotherapy is the mainstay of treatment. A number of different platinum-based chemotherapy regimens and non-platinum-based chemoth - Platinum‐containing regimens for metastatic breast cancer
Cochrane Systematic Reviews, 23-Jun-2017
Studies have reported high tumour response rates for platinum-containing regimens in the treatment of women with metastatic breast cancer. Most of these studies were conducted prior to the 'intrinsic subtype' era, and did not specifically focus on metasta - Platinum‐containing regimens for triple‐negative metastatic breast cancer
Cochrane Systematic Reviews, 21-Oct-2020
In a previous Cochrane Review, we found that for women with metastatic breast cancer unselected for triple-negative disease, there is little or no survival benefit and excess toxicity from platinum-based regimens. In subgroup analyses, however, we found p - Platinum‐induced hearing loss after treatment for childhood cancer
Cochrane Systematic Reviews, 3-Aug-2016
Platinum-based therapy, including cisplatin, carboplatin, oxaliplatin or a combination of these, is used to treat a variety of paediatric malignancies. Unfortunately, one of the most important adverse effects is the occurrence of hearing loss or ototoxici - Pleurodesis for malignant pleural effusions
Cochrane Systematic Reviews, 20-Nov-2013
Approximately half of all patients with metastatic cancer develop a malignant pleural effusion which is likely to lead to a significant reduction in quality of life secondary to symptoms such as dyspnoea and cough. The aim of pleurodesis in these patients - Plugs for containing faecal incontinence
Cochrane Systematic Reviews, 20-Jul-2015
Faecal incontinence is a distressing disorder with high social stigma. Not all people with faecal incontinence can be cured with conservative or surgical treatment and they may need to rely on containment products, such as anal plugs. - Pneumatic retinopexy versus scleral buckle for repairing simple rhegmatogenous retinal detachments
Cochrane Systematic Reviews, 11-Nov-2021
A rhegmatogenous retinal detachment (RRD) is a separation of the neurosensory retina from the retinal pigment epithelium caused by a full-thickness break associated with vitreous traction. While pneumatic retinopexy (PR), scleral buckle (SB), and vitrecto - Pneumococcal conjugate vaccines for preventing acute otitis media in children
Cochrane Systematic Reviews, 24-Nov-2020
Prior to introducing pneumococcal conjugate vaccines (PCVs), Streptococcus pneumoniae was most commonly isolated from the middle ear fluid of children with acute otitis media (AOM). Reducing nasopharyngeal colonisation of this bacterium by PCVs may lead t - Pneumococcal conjugate vaccines for preventing vaccine‐type invasive pneumococcal disease and X‐ray defined pneumonia in children less than two years of age
Cochrane Systematic Reviews, 6-Oct-2009
Pneumonia, caused by Streptococcus pneumoniae, is a major cause of morbidity and mortality among children in low-income countries. The effectiveness of pneumococcal conjugate vaccines (PCVs) against invasive pneumococcal disease (IPD), pneumonia, and mort - Pneumococcal vaccination during pregnancy for preventing infant infection
Cochrane Systematic Reviews, 23-Jan-2015
Approximately 450,000 children worldwide die of pneumococcal infections each year. The development of bacterial resistance to antimicrobials adds to the difficulty of treatment of diseases and emphasizes the need for a preventive approach. Newborn vaccina - Pneumococcal vaccine for asthma
Cochrane Systematic Reviews, 21-Jan-2002
Infection with Streptococcus pneumoniae is an important cause of pneumonia and other serious illnesses, particularly amongst those with certain high-risk medical conditions such as asthma. Although pneumococcal vaccine is routinely advocated for people wi - Pneumococcal vaccines for children and adults with bronchiectasis
Cochrane Systematic Reviews, 15-Apr-2009
Bronchiectasis is increasingly recognized as a major cause of respiratory morbidity especially in developing countries. Even in affluent countries, bronchiectasis is increasingly seen in some community subsections (e.g. Aboriginal communities) and occurs - Pneumococcal vaccines for cystic fibrosis
Cochrane Systematic Reviews, 22-Sep-2016
Invasive pneumococcal disease is associated with significant mortality and many countries have introduced routine pneumococcal vaccination into their childhood immunisation programmes. Whilst pneumococcal disease in cystic fibrosis is uncommon, pneumococc
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