- Interventions for the treatment of oral and oropharyngeal cancers: targeted therapy and immunotherapy
Cochrane Systematic Reviews, 30-Nov-2015
Oral cancers are the sixth most common cancer worldwide, yet the prognosis following a diagnosis of oral cavity or oropharyngeal cancers remains poor, with approximately 50% survival at five years. Despite a sharp increase in research into molecularly tar - Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy
Cochrane Systematic Reviews, 7-Mar-2011
Oral cavity and oropharyngeal cancers are frequently described as part of a group of oral cancers or head and neck cancer. Treatment of oral cavity cancer is generally surgery followed by radiotherapy, whereas oropharyngeal cancers, which are more likely - Interventions for the treatment of oral cavity and oropharyngeal cancer: radiotherapy
Cochrane Systematic Reviews, 9-Nov-2010
The management of advanced oral cavity and oropharyngeal cancers is problematic and has traditionally relied on surgery and radiotherapy, both of which are associated with substantial adverse effects. Radiotherapy has been in use since the 1950s and has t - Interventions for the treatment of twin-twin transfusion syndrome
Cochrane Systematic Reviews, 27-Jan-2014
Twin-twin transfusion syndrome, a condition affecting monochorionic twin pregnancies, is associated with a high risk of perinatal mortality and morbidity. A number of treatments have been introduced to treat the condition but it is unclear which intervent - Interventions for tobacco cessation in the dental setting
Cochrane Systematic Reviews, 23-Apr-2012
Tobacco use has significant adverse effects on oral health. Oral health professionals in the dental office or community setting have a unique opportunity to increase tobacco abstinence rates among tobacco users. - Interventions for tobacco use cessation in people in treatment for or recovery from substance use disorders
Cochrane Systematic Reviews, 19-Jan-2017
Smoking rates in people with alcohol and other drug dependencies are two to four times those of the general population. Concurrent treatment of tobacco dependence has been limited due to concern that these interventions are not successful in this populati - Interventions for tobacco use cessation in people living with HIV and AIDS
Cochrane Systematic Reviews, 3-Jun-2016
Tobacco use is highly prevalent amongst people living with HIV/AIDS (PLWHA) and has a substantial impact on morbidity and mortality. - Interventions for tobacco use prevention in Indigenous youth
Cochrane Systematic Reviews, 4-Jul-2012
Tobacco use in Indigenous populations (people who have inhabited a country for thousands of years) is often double that in the non-Indigenous population. Addiction to nicotine usually begins during early adolescence and young people who reach the age of 1 - Interventions for tophi in gout
Cochrane Systematic Reviews, 14-Oct-2014
Tophi develop in untreated or uncontrolled gout. Their presence can lead to severe and potentially fatal complications. To date there have been no systematic reviews focused on the management of tophi in gout. - Interventions for toxic epidermal necrolysis
Cochrane Systematic Reviews, 17-Feb-2015
Toxic epidermal necrolysis is a rare condition where a drug reaction induces skin loss, similar to that seen in extensive burns. It is associated with high morbidity and mortality and there is no clear agreement on effective treatment. - Interventions for trachoma trichiasis
Cochrane Systematic Reviews, 14-Dec-2016
Trachoma is the leading infectious cause of blindness. The World Health Organization (WHO) recommends eliminating trachomatous blindness through the SAFE strategy: Surgery for trichiasis, Antibiotic treatment, Facial cleanliness and Environmental hygiene. - Interventions for treating acute bleeding episodes in people with acquired hemophilia A
Cochrane Systematic Reviews, 15-Aug-2014
Acquired hemophilia A is a rare bleeding disorder caused by autoantibodies to coagulation factor VIII (FVIII). In most cases, bleeding episodes are spontaneous and severe at presentation. The optimal hemostatic therapy is controversial. - Interventions for treating acute elbow dislocations in adults
Cochrane Systematic Reviews, 5-Mar-2012
Dislocation of the elbow joint is a relatively uncommon injury. - Interventions for treating acute high altitude illness
Cochrane Systematic Reviews, 20-Dec-2018
Acute high altitude illness is defined as a group of cerebral and pulmonary syndromes that can occur during travel to high altitudes. It is more common above 2500 metres, but can be seen at lower elevations, especially in susceptible people. Acute high al - Interventions for treating AIDS-associated Hodgkin´s lymphoma in treatment-naive adults
Cochrane Systematic Reviews, 5-Sep-2011
Hodgkin's disease (HD) is the most common non-AIDS-defining malignancy in HIV-infected patients. Its unusually aggressive tumour behaviour includes a higher frequency of unfavourable histologic subtypes, high-stage and extranodal involvement by the time o - Interventions for treating anxiety after stroke
Cochrane Systematic Reviews, 23-May-2017
Approximately 20% of stroke patients experience clinically significant levels of anxiety at some point after stroke. Physicians can treat these patients with antidepressants or other anxiety-reducing drugs, or both, or they can provide psychological thera - Interventions for treating calcaneal fractures
Cochrane Systematic Reviews, 11-Aug-2008
Fracture of the calcaneus (os calcis or heel bone) comprises one to two per cent of all fractures. - Interventions for treating central venous haemodialysis catheter malfunction
Cochrane Systematic Reviews, 22-Oct-2017
Adequate haemodialysis (HD) in people with end-stage kidney disease (ESKD) is reliant upon establishment of vascular access, which may consist of arteriovenous fistula, arteriovenous graft, or central venous catheters (CVC). Although discouraged due to hi - Interventions for treating chronic ankle instability
Cochrane Systematic Reviews, 20-Jun-2011
Chronic lateral ankle instability occurs in 10% to 20% of people after an acute ankle sprain. Initial treatment is conservative but if this fails and ligament laxity is present, surgical intervention is considered. - Interventions for treating chronic pelvic pain in women
Cochrane Systematic Reviews, 26-Mar-2015
Chronic pelvic pain is common in women in the reproductive and older age groups and causes disability and distress. Often investigation by laparoscopy reveals no obvious cause for the pain. As the pathophysiology of chronic pelvic pain is not well underst
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