- Prophylactic antibiotic therapy for chronic bronchitis
Cochrane Systematic Reviews, 29-Nov-2013
The use of prophylactic antibiotics to reduce the frequency and severity of acute exacerbations of chronic bronchitis is controversial. - Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD)
Cochrane Systematic Reviews, 29-Oct-2018
There has been renewal of interest in the use of prophylactic antibiotics to reduce the frequency of exacerbations and improve quality of life in chronic obstructive pulmonary disease (COPD). - Prophylactic antibiotics for inhibiting preterm labour with intact membranes
Cochrane Systematic Reviews, 26-Nov-2013
The aetiology of preterm birth is complex and there is evidence that subclinical genital tract infection influences preterm labour in some women but the role of prophylactic antibiotic treatment in the management of preterm labour is controversial. Since - Prophylactic antibiotics for manual removal of retained placenta in vaginal birth
Cochrane Systematic Reviews, 15-Oct-2014
Retained placenta is a potentially life-threatening condition because of its association with postpartum hemorrhage. Manual removal of placenta increases the likelihood of bacterial contamination in the uterine cavity. - Prophylactic antibiotics for preventing Gram positive infections associated with long-term central venous catheters in oncology patients
Cochrane Systematic Reviews, 21-Sep-2016
This is an updated version of the review which was first published in the Cochrane Database of Systematic Reviews in 2006. Long-term central venous catheters (CVCs), including tunnelled CVCs (TCVCs) and totally implanted devices or ports (TIDs), are incre - Prophylactic antibiotics for transcervical intrauterine procedures
Cochrane Systematic Reviews, 31-May-2013
The transcervical intrauterine route is commonly used for operative gynaecological procedures in women. The vagina is an area of the body that is abundant with normal bacterial flora. An operative procedure through the vagina may, therefore, be considered - Prophylactic antibiotics or G(M)-CSF for the prevention of infections and improvement of survival in cancer patients receiving myelotoxic chemotherapy
Cochrane Systematic Reviews, 15-Dec-2015
Febrile neutropenia (FN) and other infectious complications are some of the most serious treatment-related toxicities of chemotherapy for cancer, with a mortality rate of 2% to 21%. The two main types of prophylactic regimens are granulocyte (macrophage) - Prophylactic antibiotics to reduce morbidity and mortality in neonates with umbilical artery catheters
Cochrane Systematic Reviews, 15-Jan-2011
Umbilical artery catheters are often used in unwell neonates. Infection related to the use of these catheters may cause significant morbidity and mortality. The use of prophylactic antibiotics has been advocated for all newborns with umbilical artery cath - Prophylactic antibiotics to reduce morbidity and mortality in neonates with umbilical venous catheters
Cochrane Systematic Reviews, 15-Jan-2011
Umbilical venous catheters (UVCs) are often used in ill neonates. Infection related to the use of these catheters may cause significant morbidity and mortality. The use of prophylactic antibiotics has been advocated for newborns with umbilical venous cath - Prophylactic antibiotics to reduce morbidity and mortality in newborn infants with intercostal catheters
Cochrane Systematic Reviews, 11-Mar-2012
Intercostal catheters are commonly used for the drainage of intrathoracic collections in newborn infants, including pneumothorax and pleural effusions. Placement of an intercostal drain is a potential risk factor for nosocomial infection due to breach of - Prophylactic antibiotics to reduce morbidity and mortality in ventilated newborn infants
Cochrane Systematic Reviews, 15-Jan-2011
Intubation is associated with bacterial colonisation of the respiratory tract and therefore may increase the risk of acquiring an infection. The infection may prolong the need for mechanical ventilation and increase the risk of chronic lung disease. The u - Prophylactic antibiotics to reduce the risk of urinary tract infections after urodynamic studies
Cochrane Systematic Reviews, 5-Sep-2012
There is a risk that people who have invasive urodynamic studies (cystometry) will develop urinary tract infections or bacteria in the urine or blood. However, the use of prophylactic antibiotics before or immediately after invasive cystometry or urodynam - Prophylactic anti-staphylococcal antibiotics for cystic fibrosis
Cochrane Systematic Reviews, 18-Apr-2017
Staphylococcus aureus causes pulmonary infection in young children with cystic fibrosis. Prophylactic antibiotics are prescribed hoping to prevent such infection and lung damage. Antibiotics have adverse effects and long-term use might lead to infection - Prophylactic barbiturate use for the prevention of morbidity and mortality following perinatal asphyxia
Cochrane Systematic Reviews, 29-Apr-2016
Seizures are common following perinatal asphyxia and may exacerbate secondary neuronal injury. Barbiturate therapy has been used for infants with perinatal asphyxia in order to prevent seizures. However, barbiturate therapy may adversely affect neurodevel - Prophylactic caffeine to prevent postoperative apnoea following general anaesthesia in preterm infants
Cochrane Systematic Reviews, 25-Feb-2013
Growing ex-preterm infants who undergo general anaesthesia for surgery at about term-equivalent age may have episodes of apnoea, cyanosis and bradycardia during the early postoperative period. A breathing stimulant such as caffeine given at the time of op - Prophylactic corticosteroids for cardiopulmonary bypass in adults
Cochrane Systematic Reviews, 5-Apr-2011
High-dose prophylactic corticosteroids are often administered during cardiac surgery. Their use, however, remains controversial, as no trials are available that have been sufficiently powered to draw conclusions on their effect on major clinical outcomes. - Prophylactic corticosteroids for preterm birth
Cochrane Systematic Reviews, 28-Oct-2008
Respiratory distress syndrome is a serious complication of prematurity causing significant immediate and long-term mortality and morbidity. - Prophylactic cranial irradiation for preventing brain metastases in patients undergoing radical treatment for non-small cell lung cancer
Cochrane Systematic Reviews, 1-Aug-2010
In non-small cell lung cancer (NSCLC), there is a relatively high incidence of brain metastases following radical treatment. At present, the role of prophylactic cranial irradiation (PCI) in this group of patients is not clear. This is an update of the or - Prophylactic doxapram for the prevention of morbidity and mortality in preterm infants undergoing endotracheal extubation
Cochrane Systematic Reviews, 25-Feb-2013
When preterm infants have been given intermittent positive pressure ventilation (IPPV) for respiratory failure, weaning from support and tracheal extubation may be difficult. A significant contributing factor is thought to be the relatively poor respirato - Prophylactic drug management for febrile seizures in children
Cochrane Systematic Reviews, 22-Feb-2017
Febrile seizures occurring in a child older than one month during an episode of fever affect 2% to 4% of children in Great Britain and the United States and recur in 30%. Rapid-acting antiepileptics and antipyretics given during subsequent fever episodes
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