- Progesterone receptor modulators for endometriosis
Cochrane Systematic Reviews, 25-Jul-2017
Endometriosis is defined as the presence of endometrial tissue (glands and stroma) outside the uterine cavity. This condition is oestrogen-dependent and thus is seen primarily during the reproductive years. Owing to their antiproliferative effects in the - Progestin-only contraceptives: effects on weight
Cochrane Systematic Reviews, 21-Aug-2016
Progestin-only contraceptives (POCs) are appropriate for many women who cannot or should not take estrogen. POCs include injectables, intrauterine contraception, implants, and oral contraceptives. Many POCs are long-acting, cost-effective methods of preve - Progestin-only pills for contraception
Cochrane Systematic Reviews, 6-Nov-2013
The introduction of a new progestin-only oral contraceptive in Europe has renewed interest in this class of oral contraceptives. Unlike the more widely used combined oral contraceptives containing an estrogen plus progestin, these pills contain only a pro - Progestogen for preventing miscarriage in women with recurrent miscarriage of unclear etiology
Cochrane Systematic Reviews, 19-Nov-2019
Progesterone, a female sex hormone, is known to induce secretory changes in the lining of the uterus essential for successful implantation of a fertilized egg. It has been suggested that a causative factor in many cases of miscarriage may be inadequate se - Progestogen for treating threatened miscarriage
Cochrane Systematic Reviews, 28-Sep-2018
Miscarriage is a common complication encountered during pregnancy. It is defined as spontaneous pregnancy loss before 20 weeks' gestation. Progesterone's physiological role is to prepare the uterus for the implantation of the embryo, enhance uterine quies - Progestogen-releasing intrauterine systems versus other forms of reversible contraceptives for contraception
Cochrane Systematic Reviews, 11-Jan-2010
Hormonally impregnated intrauterine systems (IUSs) add a progestogen to a non-medicated contraceptive device to improve contraceptive action. - Progestogens or progestogen-releasing intrauterine systems for uterine fibroids
Cochrane Systematic Reviews, 29-Jan-2013
Uterine fibroids are the most common premenopausal benign uterine tumours. Fibroids can cause symptoms including heavy menstrual bleeding, pelvic pressure and pain. Progestogens can be administered by various routes. Intramuscular injection of depot medro - Progestogens with or without oestrogen for irregular uterine bleeding associated with anovulation
Cochrane Systematic Reviews, 12-Sep-2012
Irregular menstrual bleeding may arise due to exogenous sex steroids, lesions of the genital tract or be associated with anovulation. Irregular bleeding due to oligo/anovulation (previously called dysfunctional uterine bleeding or DUB) is more common at t - Progressive resistance strength training for improving physical function in older adults
Cochrane Systematic Reviews, 11-May-2009
Muscle weakness in old age is associated with physical function decline. Progressive resistance strength training (PRT) exercises are designed to increase strength. - Progressive resistive exercise interventions for adults living with HIV/AIDS
Cochrane Systematic Reviews, 10-Nov-2008
Due to medical advancements, many people living with HIV infection in developed countries are living longer (Palella 1998). HIV infection can now present as a chronic illness with an uncertain natural disease history. The changing course of HIV infection - Prokinetics for functional dyspepsia
Cochrane Systematic Reviews, 16-Oct-2018
Dyspepsia is a common condition associated with gastrointestinal (GI) disease. Prokinetics are the treatment of choice for functional dyspepsia (FD). However, the role of prokinetics in FD treatment is still controversial. - Prolonged antibiotics for non-cystic fibrosis bronchiectasis in children and adults
Cochrane Systematic Reviews, 21-Aug-2017
The vicious cycle hypothesis for bronchiectasis predicts that bacterial colonisation of the respiratory tract perpetuates inflammatory change. This damages the mucociliary escalator, preventing bacterial clearance and allowing persistence of pro-inflammat - Prolonged storage of packed red blood cells for blood transfusion
Cochrane Systematic Reviews, 10-Jul-2015
A blood transfusion is an acute intervention, used to address life- and health-threatening conditions on a short-term basis. Packed red blood cells are most often used for blood transfusion. Sometimes blood is transfused after prolonged storage but there - Prolonged thromboprophylaxis with low molecular weight heparin for abdominal or pelvic surgery
Cochrane Systematic Reviews, 13-May-2019
This an update of the review first published in 2009. - Prolonged versus short course of indomethacin for the treatment of patent ductus arteriosus in preterm infants
Cochrane Systematic Reviews, 2-Nov-2008
Indomethacin is a prostaglandin inhibitor used to treat patent ductus arteriosus (PDA) in preterm infants. Although indomethacin produces ductal closure in the majority of cases, it is ineffective in up to 40% of patients. Furthermore, the ductus will re- - Prompted voiding for the management of urinary incontinence in adults
Cochrane Systematic Reviews, 5-Nov-2008
Prompted voiding is a behavioural therapy used mainly in North American nursing homes. It aims to improve bladder control for people with or without dementia using verbal prompts and positive reinforcement. - Prompts to encourage appointment attendance for people with serious mental illness
Cochrane Systematic Reviews, 21-Jun-2012
Prompts to encourage attendance at clinics are often used in day-to-day practice by diligent carers of people with mental health problems. These may take the form of telephone prompting, financial incentives or issuing a copy of the referral letter to the - Propentofylline for dementia
Cochrane Systematic Reviews, 16-Apr-2008
Propentofylline is a novel therapeutic agent for dementia that readily crosses the blood-brain barrier and acts by blocking the uptake of adenosine and inhibiting the enzyme phosphodiesterase. In vitro and in vivo its mechanism of action appears to be two - Prophylactic abdominal drainage for pancreatic surgery
Cochrane Systematic Reviews, 20-Jun-2018
The use of surgical drains has been considered mandatory after pancreatic surgery. The role of prophylactic abdominal drainage to reduce postoperative complications after pancreatic surgery is controversial. - Prophylactic animal derived surfactant extract for preventing morbidity and mortality in preterm infants
Cochrane Systematic Reviews, 16-Mar-2010
Respiratory distress syndrome (RDS) is caused by a deficiency or dysfunction of pulmonary surfactant. A variety of animal derived surfactant extracts have been formulated and given to infants at risk of developing RDS.
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