- Interventions for lowering plasma homocysteine levels in kidney transplant recipients
Cochrane Systematic Reviews, 24-Apr-2015
Elevated homocysteine levels have been shown to be an independent risk factor for cardiovascular disease. However studies of homocysteine lowering in general and end-stage kidney disease (ESKD) populations have not demonstrated a reduction in cardiovascul - Interventions for managing asthma in pregnancy
Cochrane Systematic Reviews, 15-Oct-2014
Asthma is the most common respiratory disorder complicating pregnancy, and is associated with a range of adverse maternal and perinatal outcomes. There is strong evidence however, that the adequate control of asthma can improve health outcomes for mothers - Interventions for managing medication-related osteonecrosis of the jaw
Cochrane Systematic Reviews, 5-Oct-2017
Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse reaction experienced by some individuals to certain medicines commonly used in the treatment of cancer and osteoporosis (e.g. bisphosphonates, denosumab and antiangiogenic agents) and - Interventions for managing relapse of the lower front teeth after orthodontic treatment
Cochrane Systematic Reviews, 11-Mar-2014
Orthodontic relapse can be defined as the tendency for teeth to return to their pre-treatment position, and this occurs especially in lower front teeth (lower canines and lower incisors). Retention, to maintain the position of corrected teeth, has become - Interventions for managing skeletal muscle spasticity following traumatic brain injury
Cochrane Systematic Reviews, 22-Nov-2017
Skeletal muscle spasticity is a major physical complication resulting from traumatic brain injury (TBI), which can lead to muscle contracture, joint stiffness, reduced range of movement, broken skin and pain. Treatments for spasticity include a range of p - Interventions for managing taste disturbances
Cochrane Systematic Reviews, 18-Dec-2017
The sense of taste is very much essential to the overall health of an individual. It is a necessary component to enjoy one's food, which in turn provides nutrition to an individual. Any disturbance in taste perception can hamper quality of life in such pa - Interventions for melasma
Cochrane Systematic Reviews, 14-Jun-2010
Melasma is an acquired symmetrical pigmentary disorder where confluent grey-brown patches typically appear on the face. Available treatments for melasma are unsatisfactory. - Interventions for men and women with their first episode of genital herpes
Cochrane Systematic Reviews, 18-Aug-2016
Genital herpes is incurable, and is caused by the herpes simplex virus (HSV). First-episode genital herpes is the first clinical presentation of herpes that a person experiences. Current treatment is based around viral suppression in order to decrease the - Interventions for Mooren's ulcer
Cochrane Systematic Reviews, 9-Jan-2014
Mooren's ulcer is a chronic, painful peripheral ulcer of the cornea. Its cause is unknown but it can or will lead to loss of vision if untreated. Severe pain is common in patients with Mooren's ulcer and the eye(s) may be intensely reddened, inflamed and - Interventions for motor apraxia following stroke
Cochrane Systematic Reviews, 25-Aug-2008
Apraxia is a cognitive disorder that can occur after stroke. It prevents a person from carrying out a learned movement. Various interventions are used to treat apraxia but evidence of their benefit has been lacking. - Interventions for mucous membrane pemphigoid and epidermolysis bullosa acquisita
Cochrane Systematic Reviews, 7-Oct-2015
Mucous membrane pemphigoid and epidermolysis bullosa acquisita are rare acquired autoimmune blistering diseases of the skin. Both can result in scarring of mucous membranes which may lead to blindness and life threatening respiratory complications. - Interventions for nail psoriasis
Cochrane Systematic Reviews, 11-Dec-2012
Psoriasis is a common skin disease that can also involve the nails. All parts of the nail and surrounding structures can become affected. The incidence of nail involvement increases with duration of psoriasis. Although it is difficult to treat psoriatic n - Interventions for necrotising pancreatitis
Cochrane Systematic Reviews, 12-Apr-2016
Acute necrotising pancreatitis carries significant mortality, morbidity, and resource use. There is considerable uncertainty as to how people with necrotising pancreatitis should be treated. - Interventions for necrotizing soft tissue infections in adults
Cochrane Systematic Reviews, 30-May-2018
Necrotizing soft tissue infections (NSTIs) are severe and rapidly spreading soft tissue infections of the subcutaneous tissue, fascia, or muscle, which are mostly caused by bacteria. Associated rates of mortality and morbidity are high, with the former es - Interventions for oropharyngeal dysphagia in children with neurological impairment
Cochrane Systematic Reviews, 11-Sep-2012
Oropharyngeal dysphagia encompasses problems with the oral preparatory phase of swallowing (chewing and preparing the food), oral phase (moving the food or fluid posteriorly through the oral cavity with the tongue into the back of the throat) and pharynge - Interventions for pain with intrauterine device insertion
Cochrane Systematic Reviews, 23-Jul-2015
Fear of pain during insertion of intrauterine contraception (IUC) is a barrier to use of this method. IUC includes copper-containing intrauterine devices and levonorgestrel-releasing intrauterine systems. Interventions for pain control during IUC insertio - Interventions for pathological gambling
Cochrane Systematic Reviews, 31-Oct-2008
With the legalization of new forms of gambling there are increasing numbers of individuals who appear to have gambling related problems and who are seeking help. - Interventions for patients and caregivers to improve knowledge of sickle cell disease and recognition of its related complications
Cochrane Systematic Reviews, 6-Oct-2016
Sickle cell disease is a group of genetic diseases which is especially prevalent in tropical and subtropical regions; however, forced migration and ongoing population movement have spread it throughout the world, with estimated birth rates reaching 0.49 p - Interventions for photodamaged skin
Cochrane Systematic Reviews, 2-Jun-2015
Photodamage describes skin changes such as fine and coarse wrinkles, roughness, freckles and pigmentation changes that occur as a result of prolonged exposure to the sun. Many treatments are available to reverse the damage, but it is unclear which work an - Interventions for pregnant women with hyperglycaemia not meeting gestational diabetes and type 2 diabetes diagnostic criteria
Cochrane Systematic Reviews, 18-Apr-2012
Pregnancy hyperglycaemia without meeting gestational diabetes mellitus (GDM) diagnostic criteria affects a significant proportion of pregnant women each year. It is associated with a range of adverse pregnancy outcomes. Although intensive management for w
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