- Printed educational materials: effects on professional practice and healthcare outcomes
Cochrane Systematic Reviews, 2-Apr-2013
Printed educational materials are widely used passive dissemination strategies to improve the quality of clinical practice and patient outcomes. Traditionally they are presented in paper formats such as monographs, publication in peer-reviewed journals an - Probing for congenital nasolacrimal duct obstruction
Cochrane Systematic Reviews, 6-Jul-2017
Congenital nasolacrimal duct obstruction (NLDO) is a common condition causing excessive tearing in the first year of life. Infants present with excessive tearing or mucoid discharge from the eyes due to blockage of the nasolacrimal duct system, which can - Probiotics for induction of remission in Crohn's disease
Cochrane Systematic Reviews, 11-May-2008
Crohn's disease has a high morbidity and there is no known cure. Current treatments have multiple side effects and an effective treatment with minimal side effects is desired. Probiotics have been proposed as such a treatment but their efficacy is undeter - Probiotics for induction of remission in ulcerative colitis
Cochrane Systematic Reviews, 26-May-2008
Ulcerative Colitis (UC) is an inflammatory condition affecting the colon with an incidence of approximately 10-20 per 100,000 per year. No existing intervention is effective in all patients with a proportion requiring colectomy. There are significant prop - Probiotics for maintenance of remission in Crohn's disease
Cochrane Systematic Reviews, 16-Jun-2008
Crohn's disease (CD) is characterised by episodes of disease activity and symptom-free remission. Probiotics are microorganisms that can potentially benefit health, and have been evaluated as an alternate means of preventing relapse in patients with CD. - Probiotics for maintenance of remission in ulcerative colitis
Cochrane Systematic Reviews, 2-Nov-2011
Ulcerative colitis is a chronic relapsing disease characterised by diffuse mucosal inflammation limited to the colon. Current maintenance treatments have multiple adverse events and an effective treatment with minimal adverse events is desired. Several st - Probiotics for non-alcoholic fatty liver disease and/or steatohepatitis
Cochrane Systematic Reviews, 9-Nov-2008
Non-alcoholic fatty liver disease comprises a spectrum of diseases ranging from simple steatosis to non-alcoholic steatohepatitis, fibrosis, and cirrhosis. Probiotics have been proposed as a treatment option because of their modulating effect on the gut f - Probiotics for preventing acute otitis media in children
Cochrane Systematic Reviews, 7-Jun-2019
Acute otitis media (AOM), or acute middle ear infection, is one of the most frequently occurring childhood diseases, and the most common reason given for prescribing antibiotics in this age group. Guidelines often recommend antibiotics as first-line treat - Probiotics for preventing acute upper respiratory tract infections
Cochrane Systematic Reviews, 2-Feb-2015
Probiotics may improve a person's health by regulating their immune function. Some trials have shown that probiotic strains can prevent respiratory infections. Even though the previous version of our review showed benefits of probiotics for acute upper re - Probiotics for preventing gestational diabetes
Cochrane Systematic Reviews, 26-Feb-2014
Gestational diabetes mellitus (GDM) is associated with a range of adverse pregnancy outcomes for mother and infant. The prevention of GDM using lifestyle interventions has proven difficult. The gut microbiome (the composite of bacteria present in the inte - Probiotics for preventing preterm labour
Cochrane Systematic Reviews, 13-Dec-2011
Preterm birth causes 60% to 80% of neonatal deaths. Survivors can experience life-long complications. Thirty to fifty per cent of preterm labours are associated with maternal infection. Probiotics are defined as live micro-organisms which, when administer - Probiotics for preventing urinary tract infection in people with neuropathic bladder
Cochrane Systematic Reviews, 8-Sep-2017
Neuropathic or neurogenic bladder describes a process of dysfunctional voiding as the result of injury in the brain, spinal cord or nerves innervating the bladder. People with neuropathic bladder, such as from spinal cord injury (SCI), are at significant - Probiotics for preventing urinary tract infections in adults and children
Cochrane Systematic Reviews, 20-Dec-2015
Urinary tract infection (UTI) is a common bacterial infection that can lead to significant morbidity including stricture, abscess formation, fistula, bacteraemia, sepsis, pyelonephritis and kidney dysfunction. Mortality rates are reported to be as high as - Probiotics for preventing ventilator-associated pneumonia
Cochrane Systematic Reviews, 24-Oct-2014
Ventilator-associated pneumonia (VAP) is common in intensive care units (ICUs). Some evidence indicates that probiotics may reduce the incidence of VAP. Several additional published studies have demonstrated that probiotics are safe and efficacious in pre - Probiotics for prevention of necrotizing enterocolitis in preterm infants
Cochrane Systematic Reviews, 10-Apr-2014
Necrotizing enterocolitis (NEC) and nosocomial sepsis are associated with increased morbidity and mortality in preterm infants. Through prevention of bacterial migration across the mucosa, competitive exclusion of pathogenic bacteria, and enhancing the im - Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children
Cochrane Systematic Reviews, 18-Dec-2017
Antibiotics can disturb gastrointestinal microbiota which may lead to reduced resistance to pathogens such as Clostridium difficile (C. difficile). Probiotics are live microbial preparations that, when administered in adequate amounts, may confer a health - Probiotics for the prevention of pediatric antibiotic-associated diarrhea
Cochrane Systematic Reviews, 13-May-2019
Antibiotics alter the microbial balance commonly resulting in antibiotic-associated diarrhea (AAD). Probiotics may prevent AAD via providing gut barrier, restoration of the gut microflora, and other potential mechanisms of action. - Probiotics for the prevention or treatment of chemotherapy- or radiotherapy-related diarrhoea in people with cancer
Cochrane Systematic Reviews, 9-Aug-2018
Treament-related diarrhoea is one of the most common and troublesome adverse effects related to chemotherapy or radiotherapy in people with cancer. Its reported incidence has been as high as 50% to 80%. Severe treatment-related diarrhoea can lead to fluid - Probiotics for the treatment of bacterial vaginosis
Cochrane Systematic Reviews, 3-Aug-2009
The dominance of lactobacilli in healthy vaginal microbiota and its depletion in bacterial vaginosis (BV) has given rise to the concept of oral or vaginal instillation of probiotic Lactobacillus strains for the management of this condition. - Probiotics for treating acute infectious diarrhoea
Cochrane Systematic Reviews, 9-Nov-2010
Probiotics may offer a safe intervention in acute infectious diarrhoea to reduce the duration and severity of the illness.
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