- Pharmacological and surgical interventions for the treatment of gastro‐oesophageal reflux in adults and children with asthma
Cochrane Systematic Reviews, 17-May-2021
Asthma and gastro-oesophageal reflux disease (GORD) are common medical conditions that frequently co-exist. GORD has been postulated as a trigger for asthma; however, evidence remains conflicting. Proposed mechanisms by which GORD causes asthma include di - Pharmacological cardioversion for atrial fibrillation and flutter
Cochrane Systematic Reviews, 15-Nov-2017
Atrial fibrillation is the commonest cardiac dysrhythmia. It is associated with significant morbidity and mortality. There are two approaches to the management of atrial fibrillation: controlling the ventricular rate or converting to sinus rhythm in the e - Pharmacological interventions for acute hepatitis B infection
Cochrane Systematic Reviews, 21-Mar-2017
Infection with hepatitis B virus (HBV) can be symptomatic or asymptomatic. Apart from chronic HBV infection, the complications related to acute HBV infection are severe acute viral hepatitis and fulminant hepatitis characterised by liver failure. The opti - Pharmacological interventions for acute hepatitis C infection
Cochrane Systematic Reviews, 3-Dec-2018
Hepatitis C virus (HCV) is a single-stranded RNA (ribonucleic acid) virus that has the potential to cause inflammation of the liver. The traditional definition of acute HCV infection is the first six months following infection with the virus. Another comm - Pharmacological interventions for acute pancreatitis
Cochrane Systematic Reviews, 21-Apr-2017
In people with acute pancreatitis, it is unclear what the role should be for medical treatment as an addition to supportive care such as fluid and electrolyte balance and organ support in people with organ failure. - Pharmacological interventions for alcoholic liver disease (alcohol-related liver disease)
Cochrane Systematic Reviews, 12-Apr-2017
Alcohol-related liver disease is due to excessive alcohol consumption. It includes a spectrum of liver diseases such as alcohol-related fatty liver, alcoholic hepatitis, and alcoholic cirrhosis. Mortality associated with alcoholic hepatitis is high. The o - Pharmacological interventions for antisocial personality disorder
Cochrane Systematic Reviews, 3-Sep-2020
Antisocial personality disorder (AsPD) is associated with rule-breaking, criminality, substance use, unemployment, relationship difficulties, and premature death. Certain types of medication (drugs) may help people with AsPD. This review updates a previou - Pharmacological interventions for apathy in Alzheimer's disease
Cochrane Systematic Reviews, 4-May-2018
Despite the high prevalence of apathy in Alzheimer’s disease (AD), and its harmful effects, there are currently no therapies proven to treat this symptom. Recently, a number of pharmacological therapies have been investigated as potential treatments for a - Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users
Cochrane Systematic Reviews, 15-Mar-2018
Prolonged treatment with benzodiazepines is common practice despite clinical recommendations of short-term use. Benzodiazepines are used by approximately 4% of the general population, with increased prevalence in psychiatric populations and the elderly. A - Pharmacological interventions for benzodiazepine mono-dependence management in outpatient settings
Cochrane Systematic Reviews, 18-Jun-2013
The items with X are considered "more relevant", that is the review has to stick to them to allow publication. The others have to be considered as strong suggestions to improve the readability and clarity of the review, but the reviewers can consider if - Pharmacological interventions for borderline personality disorder
Cochrane Systematic Reviews, 16-Jun-2010
Drugs are widely used in borderline personality disorder (BPD) treatment, chosen because of properties known from other psychiatric disorders ("off-label use"), mostly targeting affective or impulsive symptom clusters. - Pharmacological interventions for clozapine-induced hypersalivation
Cochrane Systematic Reviews, 18-Jan-2012
Clozapine is widely used for people with schizophrenia. Although agranulocytosis, weight gain, and cardiac problems are serious problems associated with its use, hypersalivation, sometimes of a gross and socially unacceptable quantity, is also common (30- - Pharmacological interventions for clozapine-induced sinus tachycardia
Cochrane Systematic Reviews, 27-May-2016
Clozapine is an efficacious treatment for treatment-resistant schizophrenia; however its use can be limited by side effect intolerability. Sinus tachycardia is a common adverse event associated with clozapine treatment. Various pharmacological treatments - Pharmacological interventions for cognitive decline in people with Down syndrome
Cochrane Systematic Reviews, 29-Oct-2015
People with Down syndrome are vulnerable to developing dementia at an earlier age than the general population. Alzheimer's disease and cognitive decline in people with Down syndrome can place a significant burden on both the person with Down syndrome and - Pharmacological interventions for drug-using offenders
Cochrane Systematic Reviews, 2-Jun-2015
The review represents one in a family of four reviews focusing on a range of different interventions for drug-using offenders. This specific review considers pharmacological interventions aimed at reducing drug use or criminal activity, or both, for illic - Pharmacological interventions for epilepsy in people with intellectual disabilities
Cochrane Systematic Reviews, 3-Sep-2015
The prevalence of epilepsy among people with intellectual disabilities is much higher than in the general population. Seizures in this population are often complex and refractory to treatment and antiepileptic medication may have a profound effect upon be - Pharmacological interventions for generalised itching (not caused by systemic disease or skin lesions) in pregnancy
Cochrane Systematic Reviews, 19-Feb-2016
Generalised itching is one of the most common dermatological symptoms in pregnant women. Having itchy skin during pregnancy may be very frustrating and can lead to poor sleep, exhaustion and impaired quality of life. There is a need for a systematic revie - Pharmacological interventions for heart failure in people with chronic kidney disease
Cochrane Systematic Reviews, 27-Feb-2020
Approximately half of people with heart failure have chronic kidney disease (CKD). Pharmacological interventions for heart failure in people with CKD have the potential to reduce death (any cause) or hospitalisations for decompensated heart failure. Howev - Pharmacological interventions for hypertension in children
Cochrane Systematic Reviews, 25-Jan-2014
Hypertension is a major risk factor for stroke, coronary artery disease and kidney damage in adults. There is a paucity of data on the long-term sequelae of persistent hypertension in children, but it is known that children with hypertension have evidence - Pharmacological interventions for hypertensive emergencies
Cochrane Systematic Reviews, 23-Jan-2008
Hypertensive emergencies, marked hypertension associated with acute end-organ damage, are life-threatening conditions. Many anti-hypertensive drugs have been used in these clinical settings. The benefits and harms of such treatment and the best first-line
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