- Pharmacotherapy for hypertension in adults 60 years or older
Cochrane Systematic Reviews, 5-Jun-2019
This is the second substantive update of this review. It was originally published in 1998 and was previously updated in 2009. Elevated blood pressure (known as 'hypertension') increases with age - most rapidly over age 60. Systolic hypertension is more st - Pharmacotherapy for hypertension in adults aged 18 to 59 years
Cochrane Systematic Reviews, 16-Aug-2017
Hypertension is an important risk factor for adverse cardiovascular events including stroke, myocardial infarction, heart failure and renal failure. The main goal of treatment is to reduce these events. Systematic reviews have shown proven benefit of anti - Pharmacotherapy for hypertension in women of different races
Cochrane Systematic Reviews, 24-Apr-2000
Although hypertension treatment in women is recommended to decrease the risk of cardiovascular disease (Wenger 1993, Kaplan 1995, Kuhn 1993, Hayes 1998, JNCVI,1997), the evidence for treatment benefit is primarily based on combined results for men and wom - Pharmacotherapy for hypertension‐induced left ventricular hypertrophy
Cochrane Systematic Reviews, 10-Oct-2021
Hypertension is the leading preventable risk factor for cardiovascular disease and premature death worldwide. One of the clinical effects of hypertension is left ventricular hypertrophy (LVH), a process of cardiac remodelling. It is estimated that over 30 - Pharmacotherapy for hyperuricaemia in hypertensive patients
Cochrane Systematic Reviews, 2-Sep-2020
This is the second update of this systematic review. High blood pressure represents a major public health problem. Worldwide, approximately one-fourth of the adult population has hypertension. Epidemiological and experimental studies suggest a link betwee - Pharmacotherapy for mild hypertension
Cochrane Systematic Reviews, 15-Aug-2012
People with no previous cardiovascular events or cardiovascular disease represent a primary prevention population. The benefits and harms of treating mild hypertension in primary prevention patients are not known at present. This review examines the exist - Pharmacotherapy for patellofemoral pain syndrome
Cochrane Systematic Reviews, 19-Jul-2004
Patellofemoral pain syndrome (PFPS) is common among adolescents and young adults. It is characterised by pain behind or around the patella and crepitations, provoked by ascending or descending stairs, squatting, prolonged sitting with flexed knees, runnin - Pharmacotherapy for post traumatic stress disorder (PTSD)
Cochrane Systematic Reviews, 2-Mar-2022
Posttraumatic stress disorder (PTSD) is a prevalent and disabling disorder. Evidence that PTSD is characterised by specific psychobiological dysfunctions has contributed to a growing interest in the use of medication in its treatment. - Pharmacotherapy for sleep bruxism
Cochrane Systematic Reviews, 13-Oct-2014
Sleep bruxism is an oral activity characterized by involuntary teeth grinding or clenching during sleep. Several forms of treatment have been proposed for this disorder, including behavioural, dental and pharmacological strategies. - Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers
Cochrane Systematic Reviews, 30-Nov-2021
- Pharmacotherapy for social anxiety disorder (SAnD)
Cochrane Systematic Reviews, 19-Oct-2017
Recognition is growing that social anxiety disorder (SAnD) is a chronic and disabling disorder, and data from early trials demonstrate that medication may be effective in its treatment. This systematic review is an update of an earlier review of pharmacot - Pharmacotherapy for the prevention of chronic pain after surgery in adults
Cochrane Systematic Reviews, 24-Jul-2013
Chronic pain can often occur after surgery, substantially impairing patients’ health and quality of life. It is caused by complex mechanisms that are not yet well understood. The predictable nature of most surgical procedures has allowed for the conduct o - Pharmacotherapy for trichotillomania
Cochrane Systematic Reviews, 28-Sep-2021
Trichotillomania (TTM; hair-pulling disorder) is a prevalent and disabling disorder characterised by recurrent hair-pulling. Here we update a previous Cochrane Review on the effects of medication for TTM. - Pharmacotherapy for weight loss in adults with type 2 diabetes mellitus
Cochrane Systematic Reviews, 24-Jan-2005
Obesity is closely related to type 2 diabetes and long-term weight reduction is an important part of the care delivered to obese persons with diabetes. - Pharmacy‐based management for depression in adults
Cochrane Systematic Reviews, 23-Dec-2019
It is common for people not to take antidepressant medication as prescribed, with around 50% of people likely to prematurely discontinue taking their medication after six months. Community pharmacists may be well placed to have a role in antidepressant ma - Pharyngeal instillation of surfactant before the first breath for prevention of morbidity and mortality in preterm infants at risk of respiratory distress syndrome
Cochrane Systematic Reviews, 14-Feb-2011
Intrapartum pharyngeal instillation of surfactant before the first breath may result in surfactant administration to the infant lung, with the potential benefit of avoiding endotracheal intubation and ventilation, ventilator induced lung injury and bronch - Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage
Cochrane Systematic Reviews, 20-Jan-2010
Preterm infants are at risk of periventricular haemorrhage (PVH). Phenobarbital might prevent ischaemic injury or reduce fluctuations in blood pressure and blood flow in the brain. - Phenobarbitone versus phenytoin monotherapy for epilepsy: an individual participant data review
Cochrane Systematic Reviews, 31-Jul-2019
This is an update of a Cochrane Review first published in 2001, and last updated in 2013. This review is one in a series of Cochrane Reviews investigating pair-wise monotherapy comparisons. - Phenytoin for neuropathic pain and fibromyalgia in adults
Cochrane Systematic Reviews, 29-May-2019
Antiepileptic drugs have been used in pain management since the 1960s; some have shown efficacy in treating different neuropathic pain conditions. Phenytoin is an established antiepileptic drug that has been used occasionally to treat intractable trigemin - Phlebotonics for haemorrhoids
Cochrane Systematic Reviews, 9-Jul-2012
Haemorrhoids are variceal dilatations of the anal and perianal venous plexus and often develop secondary to the persistently elevated venous pressure within the haemorrhoidal plexus (Kumar 2005). Phlebotonics are a heterogenous class of drugs consisting o
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