- Immunoglobulins, vaccines or interferon for preventing cytomegalovirus disease in solid organ transplant recipients
Cochrane Systematic Reviews, 17-Mar-2010
Cytomegalovirus (CMV) is the most common virus causing disease and death in solid organ transplant recipients during the first six months post-transplant. Previous systematic reviews have demonstrated the efficacy of antiviral medications used prophylacti - Immunomodulators and immunosuppressants for multiple sclerosis: a network meta-analysis
Cochrane Systematic Reviews, 17-May-2013
Different therapeutic strategies are available for treatment of multiple sclerosis (MS) including immunosuppressants, immunomodulators, and monoclonal antibodies. Their relative effectiveness in the prevention of relapse or disability progression is uncle - Immunomodulators and immunosuppressants for relapsing-remitting multiple sclerosis: a network meta-analysis
Cochrane Systematic Reviews, 16-Sep-2015
Different therapeutic strategies are available for the treatment of people with relapsing-remitting multiple sclerosis (RRMS), including immunomodulators, immunosuppressants and biologics. Although there is consensus that these therapies reduce the freque - Immunomodulatory interventions for focal epilepsy syndromes
Cochrane Systematic Reviews, 26-Jun-2013
Epilepsy is a common neurological disorder made particularly disabling in the 30% of patients who do not achieve freedom from seizures despite multiple trials of antiepileptic drugs (AEDs). Experimental and clinical evidence supports a role for inflammato - Immunonutrition for patients undergoing surgery for head and neck cancer
Cochrane Systematic Reviews, 23-Aug-2018
Patients with head and neck cancer are often malnourished. Surgery for such cancers is complex and may be undertaken after a course of radiotherapy. As a result, patients may have postoperative complications such as fistulae and wound infections, as well - Immunosuppressants for the prophylaxis of corneal graft rejection after penetrating keratoplasty
Cochrane Systematic Reviews, 25-Aug-2015
Penetrating keratoplasty is a corneal transplantation procedure in which a full-thickness cornea from the host is replaced by a graft from a donor. The use of various immunosuppressants to prevent graft rejection, the most common cause of graft failure in - Immunosuppressive agents for myasthenia gravis
Cochrane Systematic Reviews, 2-Nov-2008
The benefits of different immunosuppressants for myasthenia gravis (MG) are unclear. - Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis
Cochrane Systematic Reviews, 27-Jul-2008
Immunosuppressive and cytotoxic agents have been used as both an alternative to oral corticosteroids, and as a means of maintaining a low dose of steroids in the treatment of pulmonary sarcoidosis. - Immunosuppressive T-cell antibody induction for heart transplant recipients
Cochrane Systematic Reviews, 1-Dec-2013
Heart transplantation has become a valuable and well-accepted treatment option for end-stage heart failure. Rejection of the transplanted heart by the recipient's body is a risk to the success of the procedure, and life-long immunosuppression is necessary - Immunosuppressive treatment for idiopathic membranous nephropathy in adults with nephrotic syndrome
Cochrane Systematic Reviews, 19-Nov-2014
Idiopathic membranous nephropathy (IMN) is the most common form of nephrotic syndrome in adults. The disease shows a benign or indolent course in the majority of patients, with a rate of spontaneous complete or partial remission of nephrotic syndrome as h - Immunosuppressive treatment for non-systemic vasculitic neuropathy
Cochrane Systematic Reviews, 3-Apr-2013
Non-systemic vasculitic neuropathy is a rare disabling disease that usually has a subacute onset of progressive or relapsing-remitting sensory or sensorimotor deficits. Asymmetry, pain and weakness are key features. The diagnosis can only be made by exclu - Immunotherapy (excluding checkpoint inhibitors) for stage I to III non-small cell lung cancer treated with surgery or radiotherapy with curative intent
Cochrane Systematic Reviews, 15-Dec-2017
Non-small cell lung cancer (NSCLC) is the most common lung cancer, accounting for approximately 80% to 85% of all cases. For patients with localised NSCLC (stages I to III), it has been speculated that immunotherapy may be helpful for reducing postoperati - Immunotherapy for advanced renal cell cancer
Cochrane Systematic Reviews, 29-Dec-2015
The course of advanced renal cell carcinoma is extremely variable, ranging from spontaneous remission to disease progression refractory to chemotherapy. Immunotherapy has held promise of improved outcomes based on uncontrolled studies and randomized contr - Immunotherapy for idiopathic lumbosacral plexopathy
Cochrane Systematic Reviews, 21-Dec-2013
Idiopathic lumbosacral plexopathy (ILSP), also called lumbosacral plexitis or non-diabetic lumbosacral (radiculo)plexus neuropathy is a rare clinical entity. The core features are (sub)acute, severe, asymmetrical leg pain, followed by asymmetrical multifo - Immunotherapy for IgM anti-myelin-associated glycoprotein paraprotein-associated peripheral neuropathies
Cochrane Systematic Reviews, 3-Oct-2016
Serum monoclonal anti-myelin-associated glycoprotein (anti-MAG) antibodies may be pathogenic in some people with immunoglobulin M (IgM) paraprotein and demyelinating neuropathy. Immunotherapies aimed at reducing the level of these antibodies might be expe - Immunotherapy for metastatic renal cell carcinoma
Cochrane Systematic Reviews, 15-May-2017
Since the mid-2000s, the field of metastatic renal cell carcinoma (mRCC) has experienced a paradigm shift from non-specific therapy with broad-acting cytokines to specific regimens, which directly target the cancer, the tumour microenvironment, or both. - Impact of Haemophilus influenzae type B (Hib) and viral influenza vaccinations in pregnancy for improving maternal, neonatal and infant health outcomes
Cochrane Systematic Reviews, 5-Jun-2015
Infections during pregnancy confers increased risk of maternal and perinatal morbidity and mortality. However, the case for advocating Haemophilus influenzae type B (Hib) and viral Influenza vaccinations in pregnancy is still debatable. - Impact of institutional smoking bans on reducing harms and secondhand smoke exposure
Cochrane Systematic Reviews, 25-May-2016
Smoking bans or restrictions can assist in eliminating nonsmokers' exposure to the dangers of secondhand smoke and can reduce tobacco consumption amongst smokers themselves. Evidence exists identifying the impact of tobacco control regulations and interve - Impact of morphine, fentanyl, oxycodone or codeine on patient consciousness, appetite and thirst when used to treat cancer pain
Cochrane Systematic Reviews, 28-May-2019
There is increasing focus on providing high quality care for people at the end of life, irrespective of disease or cause, and in all settings. In the last ten years the use of care pathways to aid those treating patients at the end of life has become comm - Implantable loop recorder versus conventional diagnostic workup for unexplained recurrent syncope
Cochrane Systematic Reviews, 18-Apr-2016
The most recent syncope guideline recommends that implantable loop recorders (ILRs) are implanted in the early phase of evaluation of people with recurrent syncope of uncertain origin in the absence of high-risk criteria, and in high-risk patients after a
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