- Pharmacotherapies that specifically target ammonia for the prevention and treatment of hepatic encephalopathy in adults with cirrhosis
Cochrane Systematic Reviews, 16-Jul-2019
Hepatic encephalopathy is a common complication of cirrhosis, with high related morbidity and mortality. Its presence is associated with a wide spectrum of change ranging from clinically obvious neuropsychiatric features, known as 'overt' hepatic encephal - Pharmacotherapy and psychotherapy for body dysmorphic disorder
Cochrane Systematic Reviews, 12-Nov-2008
Body dysmorphic disorder (BDD) is a prevalent and disabling preoccupation with a slight or imagined defect in appearance. Trials have investigated the use of serotonin reuptake inhibitors (SRIs) and cognitive behaviour therapy (CBT) for BDD. - Pharmacotherapy augmentation strategies in treatment-resistant anxiety disorders
Cochrane Systematic Reviews, 2-Nov-2008
A large proportion of patients with anxiety disorders fail to respond to first-line medication interventions, despite evidence of the effectiveness of these agents. - Pharmacotherapy for anxiety and comorbid alcohol use disorders
Cochrane Systematic Reviews, 20-Jan-2015
Anxiety disorders are a potentially disabling group of disorders that frequently co-occur with alcohol use disorders. Comorbid anxiety and alcohol use disorders are associated with poorer outcomes, and are difficult to treat with standard psychosocial int - Pharmacotherapy for anxiety disorders in children and adolescents
Cochrane Systematic Reviews, 10-May-2010
Anxiety disorders are a potentially disabling group of disorders which are prevalent in childhood and adolescence. The recognition of the early onset of anxiety disorders, and their successful treatment with medication in adults, has led to the growing in - Pharmacotherapy for Behcet's syndrome
Cochrane Systematic Reviews, 8-Nov-2008
Behcet's syndrome is a multisystemic disorder presenting with recurrent oral and genital ulcerations as well as ocular involvement. Treatment of Behcet's syndrome is symptomatic and empirical. - Pharmacotherapy for chronic cognitive impairment in traumatic brain injury
Cochrane Systematic Reviews, 30-Nov-2015
Traumatic brain injury (TBI) is a major cause of chronic disability. Worldwide, it is the leading cause of disability in the under 40s, resulting in severe disability in some 150 to 200 million people per annum. In addition to mood and behavioural problem - Pharmacotherapy for hypertension in adults 60 years or older
Cochrane Systematic Reviews, 5-Jun-2019
This is the second substantive update of this review. It was originally published in 1998 and was previously updated in 2009. Elevated blood pressure (known as 'hypertension') increases with age - most rapidly over age 60. Systolic hypertension is more st - Pharmacotherapy for hypertension in adults aged 18 to 59 years
Cochrane Systematic Reviews, 16-Aug-2017
Hypertension is an important risk factor for adverse cardiovascular events including stroke, myocardial infarction, heart failure and renal failure. The main goal of treatment is to reduce these events. Systematic reviews have shown proven benefit of anti - Pharmacotherapy for hypertension in women of different races
Cochrane Systematic Reviews, 12-Aug-2008
Although hypertension treatment in women is recommended to decrease the risk of cardiovascular disease (Wenger 1993, Kaplan 1995, Kuhn 1993, Hayes 1998, JNCVI,1997), the evidence for treatment benefit is primarily based on combined results for men and wom - Pharmacotherapy for hyperuricemia in hypertensive patients
Cochrane Systematic Reviews, 13-Apr-2017
High blood pressure represents a major public health problem. Worldwide, approximately one-fourth of the adult population has hypertension. Epidemiological and experimental studies suggest a link between hyperuricemia and hypertension. Hyperuricemia affec - Pharmacotherapy for mild hypertension
Cochrane Systematic Reviews, 31-May-2014
People with no previous cardiovascular events or cardiovascular disease represent a primary prevention population. The benefits and harms of treating mild hypertension in primary prevention patients are not known at present. This review examines the exist - Pharmacotherapy for patellofemoral pain syndrome
Cochrane Systematic Reviews, 11-Aug-2008
Patellofemoral pain syndrome (PFPS) is common among adolescents and young adults. It is characterised by pain behind or around the patella and crepitations, provoked by ascending or descending stairs, squatting, prolonged sitting with flexed knees, runnin - Pharmacotherapy for post traumatic stress disorder (PTSD)
Cochrane Systematic Reviews, 12-Apr-2016
Post traumatic stress disorder (PTSD) is a prevalent and disabling disorder. Evidence that PTSD is characterised by specific psychobiological dysfunctions has contributed to a growing interest in the use of medication in its treatment. - Pharmacotherapy for sleep bruxism
Cochrane Systematic Reviews, 13-Oct-2014
Sleep bruxism is an oral activity characterized by involuntary teeth grinding or clenching during sleep. Several forms of treatment have been proposed for this disorder, including behavioural, dental and pharmacological strategies. - Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers
Cochrane Systematic Reviews, 26-Feb-2018
Smoking cessation therapies are not effective for all smokers, and researchers are interested in identifying those subgroups of individuals (e.g. based on genotype) who respond best to specific treatments. - Pharmacotherapy for social anxiety disorder (SAnD)
Cochrane Systematic Reviews, 25-Jan-2019
Recognition is growing that social anxiety disorder (SAnD) is a chronic and disabling disorder, and data from early trials demonstrate that medication may be effective in its treatment. This systematic review is an update of an earlier review of pharmacot - Pharmacotherapy for the prevention of chronic pain after surgery in adults
Cochrane Systematic Reviews, 12-Jun-2017
Chronic pain can often occur after surgery, substantially impairing patients’ health and quality of life. It is caused by complex mechanisms that are not yet well understood. The predictable nature of most surgical procedures has allowed for the conduct o - Pharmacotherapy for trichotillomania
Cochrane Systematic Reviews, 7-Nov-2013
Trichotillomania (TTM) (hair-pulling disorder) is a prevalent and disabling disorder characterised by recurrent hair-pulling. The effect of medication on trichotillomania has not been systematically evaluated. - Pharmacotherapy for weight loss in adults with type 2 diabetes mellitus
Cochrane Systematic Reviews, 14-May-2009
Obesity is closely related to type 2 diabetes and long-term weight reduction is an important part of the care delivered to obese persons with diabetes.
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