- Perioperative administration of buffered versus non‐buffered crystalloid intravenous fluid to improve outcomes following adult surgical procedures
Cochrane Systematic Reviews, 8-Mar-2018
Perioperative fluid strategies influence clinical outcomes following major surgery. Many intravenous fluid preparations are based on simple solutions, such as normal saline, that feature an electrolyte composition that differs from that of physiological p - Perioperative alcohol cessation intervention for postoperative complications
Cochrane Systematic Reviews, 7-Nov-2018
Risky consumption of alcohol is a global problem. More than 3.3 million deaths annually are associated with risky use of alcohol, and global alcohol consumption continues to increase. People who have high alcohol consumption often require planned and emer - Perioperative angiotensin-converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing mortality and morbidity in adults
Cochrane Systematic Reviews, 3-Apr-2017
Perioperative hypertension requires careful management. Angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II type 1 receptor blockers (ARBs) have shown efficacy in treating hypertension associated with surgery. However, there is lack of cons - Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients
Cochrane Systematic Reviews,
Solid organ transplant recipients are at high risk for infections due to the complexity of surgical procedures combined with the impact of immunosuppression. No consensus exists on the role of antibiotics for surgical site infections in solid organ transp - Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery
Cochrane Systematic Reviews, 31-Jan-2017
Endophthalmitis is a severe inflammation of the anterior or posterior (or both) chambers of the eye that may be sterile or associated with infection. It is a potentially vision-threatening complication of cataract surgery. Prophylactic measures for endoph - Perioperative antibiotics to prevent infection after first-trimester abortion
Cochrane Systematic Reviews, 6-Feb-2012
There are two main strategies for the prevention of post-abortal upper genital tract infection: antibiotics given around the time of surgery for all women; and 'screen-and-treat', in which all women presenting for abortion are screened for genital infecti - Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity
Cochrane Systematic Reviews, 6-Mar-2018
Randomized controlled trials have yielded conflicting results regarding the ability of beta-blockers to influence perioperative cardiovascular morbidity and mortality. Thus routine prescription of these drugs in unselected patients remains a controversial - Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing cardiac surgery
Cochrane Systematic Reviews, 7-Oct-2019
Randomized controlled trials (RCTs) have yielded conflicting results regarding the ability of beta-blockers to influence perioperative cardiovascular morbidity and mortality. Thus routine prescription of these drugs in unselected patients remains a contro - Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing non‐cardiac surgery
Cochrane Systematic Reviews, 24-Sep-2019
Randomized controlled trials (RCTs) have yielded conflicting results regarding the ability of beta-blockers to influence perioperative cardiovascular morbidity and mortality. Thus routine prescription of these drugs in an unselected population remains a c - Perioperative blood transfusions and recurrence of colorectal cancer
Cochrane Systematic Reviews, 16-Feb-2011
The improvement of renal allograft survival by pre-transplantation transfusions alerted to the potential detrimental effect of transfusions in cancer treatment. - Perioperative chemo(radio)therapy versus primary surgery for resectable adenocarcinoma of the stomach, gastroesophageal junction, and lower esophagus
Cochrane Systematic Reviews, 22-Mar-2013
The outcome of patients with locally advanced gastroesophageal adenocarcinoma (adenocarcinoma of the esophagus, gastroesophageal (GE) junction, and stomach) is poor. There is conflicting evidence regarding the effects of perioperative chemotherapy on surv - Perioperative corticosteroids for preventing complications following facial plastic surgery
Cochrane Systematic Reviews, 2-Jun-2014
Early recovery is an important factor for people undergoing facial plastic surgery. However, the normal inflammatory processes that are a consequence of surgery commonly cause oedema (swelling) and ecchymosis (bruising), which are undesirable complication - Perioperative dexmedetomidine for acute pain after abdominal surgery in adults
Cochrane Systematic Reviews, 17-Feb-2016
Acute postoperative pain is still an issue in patients undergoing abdominal surgery. Postoperative pain and side effects of analgesic treatment, in particular those of opioids, need to be minimized. Opioid-sparing analgesics, possibly including dexmedetom - Perioperative enhanced recovery programmes for gynaecological cancer patients
Cochrane Systematic Reviews, 15-Nov-2018
Gynaecological malignancies contribute to 10% to 15% of cancers in women internationally. In recent years, a trend towards new perioperative care strategies has been documented as 'Fast Track (FT) surgery', or 'Enhanced Recovery Programmes' to replace som - Perioperative fluid volume optimization following proximal femoral fracture
Cochrane Systematic Reviews, 11-Mar-2016
Proximal femoral fracture (PFF) is a common orthopaedic emergency that affects mainly elderly people at high risk of complications. Advanced methods for managing fluid therapy during treatment for PFF are available, but their role in reducing risk is uncl - Perioperative glycaemic control for diabetic patients undergoing surgery
Cochrane Systematic Reviews, 30-Jul-2012
Patients with diabetes mellitus are at increased risk of postoperative complications. Data from randomised clinical trials and meta-analyses point to a potential benefit of intensive glycaemic control, targeting near-normal blood glucose, in patients with - Peri‐operative glycaemic control regimens for preventing surgical site infections in adults
Cochrane Systematic Reviews, 12-May-2009
Surgical site infections (SSIs) are associated with significant morbidity, mortality, and resource utilization and are potentially preventable. Peri-operative hyperglycaemia has been associated with increased SSIs and previous recommendations have been to - Perioperative increase in global blood flow to explicit defined goals and outcomes following surgery
Cochrane Systematic Reviews, 7-Oct-2016
Studies have suggested that increasing whole body blood flow and oxygen delivery around the time of surgery reduces mortality, morbidity and the expense of major operations. - Perioperative interventions in pelvic organ prolapse surgery
Cochrane Systematic Reviews, 17-Aug-2018
Pelvic organ prolapse (POP) affects as many as 50% of parous women, with 14% to 19% of women undergoing a surgical correction. Although surgery for the treatment of POP is common, limited supportive data can be found in the literature regarding the preope - Perioperative intravenous ketamine for acute postoperative pain in adults
Cochrane Systematic Reviews,
Inadequate pain management after surgery increases the risk of postoperative complications and may predispose for chronic postsurgical pain. Perioperative ketamine may enhance conventional analgesics in the acute postoperative setting.
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