- Palliative interventions for controlling vaginal bleeding in advanced cervical cancer
Cochrane Systematic Reviews, 19-Mar-2019
This is an updated version of the original Cochrane review published in Issue 5, 2015. - Palliative pharmacological sedation for terminally ill adults
Cochrane Systematic Reviews, 2-Jan-2015
Terminally ill people experience a variety of symptoms in the last hours and days of life, including delirium, agitation, anxiety, terminal restlessness, dyspnoea, pain, vomiting, and psychological and physical distress. In the terminal phase of life, the - Palliative radiotherapy regimens for patients with thoracic symptoms from non‐small cell lung cancer
Cochrane Systematic Reviews, 14-Jan-2015
Palliative radiotherapy to the chest is often used in patients with lung cancer, but radiotherapy regimens are more often based on tradition than research results. This is an update of a Cochrane review first published in 2001 and previously updated in 20 - Palliative surgery versus medical management for bowel obstruction in ovarian cancer
Cochrane Systematic Reviews, 7-Jul-2010
Ovarian cancer is the sixth most common cancer among women and is usually diagnosed at an advanced stage. Bowel obstruction is a common feature of advanced or recurrent ovarian cancer. Patients with bowel obstruction are generally in poor physical conditi - Pancreatic duct guidewire placement for biliary cannulation for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis
Cochrane Systematic Reviews, 24-May-2016
Difficult cannulation is a risk factor for post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP). It has been postulated that the pancreatic duct guidewire (PGW) technique may improve biliary cannulation success and reduce the risk - Pancreatic enzyme replacement therapy for people with cystic fibrosis
Cochrane Systematic Reviews, 6-Aug-2020
Most people with cystic fibrosis (CF) (80% to 90%) need pancreatic enzyme replacement therapy (PERT) to prevent malnutrition. Enzyme preparations need to be taken whenever food is taken, and the dose needs to be adjusted according to the food consumed. A - Pancreatic enzymes for chronic pancreatitis
Cochrane Systematic Reviews, 7-Oct-2009
The efficacy of pancreatic enzymes in reducing pain and improving steatorrhoea is debatable and the evidence base for their utility needs to be determined. - Pancreaticojejunostomy versus pancreaticogastrostomy reconstruction for the prevention of postoperative pancreatic fistula following pancreaticoduodenectomy
Cochrane Systematic Reviews, 12-Sep-2017
Pancreatoduodenectomy is a surgical procedure used to treat diseases of the pancreatic head and, less often, the duodenum. The most common disease treated is cancer, but pancreatoduodenectomy is also used for people with traumatic lesions and chronic panc - Paracervical local anaesthesia for cervical dilatation and uterine intervention
Cochrane Systematic Reviews, 26-Sep-2013
Cervical dilatation and uterine intervention can be performed under sedation, local or general anaesthesia for obstetrics and gynaecological conditions. Many gynaecologists use paracervical local anaesthesia but its effectiveness is unclear. This review w - Paracetamol (acetaminophen) for acute treatment of episodic tension‐type headache in adults
Cochrane Systematic Reviews, 16-Jun-2016
Tension-type headache (TTH) affects about 1 person in 5 worldwide. It is divided into infrequent episodic TTH (fewer than one headache per month), frequent episodic TTH (two to 14 headaches per month), and chronic TTH (15 headache days a month or more). P - Paracetamol (acetaminophen) for chronic non‐cancer pain in children and adolescents
Cochrane Systematic Reviews, 2-Aug-2017
Pain is a common feature of childhood and adolescence around the world, and for many young people, that pain is chronic. The World Health Organization guidelines for pharmacological treatments for children's persisting pain acknowledge that pain in childr - Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants
Cochrane Systematic Reviews, 27-Jan-2020
In preterm newborns, the ductus arteriosus frequently fails to close and the infants require medical or surgical closure of the patent ductus arteriosus (PDA). A PDA can be treated surgically; or medically with one of two prostaglandin inhibitors, indomet - Paracetamol (acetaminophen) for prevention or treatment of pain in newborns
Cochrane Systematic Reviews, 27-Jan-2020
Newborn infants have the ability to experience pain. Hospitalised infants are exposed to numerous painful procedures. Healthy newborns are exposed to pain if the birth process consists of assisted vaginal birth by vacuum extraction or by forceps and durin - Paracetamol (acetaminophen) or non‐steroidal anti‐inflammatory drugs, alone or combined, for pain relief in acute otitis media in children
Cochrane Systematic Reviews, 15-Dec-2016
Acute otitis media (AOM) is one of the most common childhood infectious diseases and a significant reason for antibiotic prescriptions in children worldwide. Pain from middle ear infection and pressure behind the eardrum is the key symptom of AOM. Ear pai - Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults
Cochrane Systematic Reviews, 30-Apr-2013
This is an updated version of the original Cochrane review published in Issue 11, 2010 (Derry 2010). Migraine is a common, disabling condition and a burden for the individual, health services and society. Many sufferers choose not to, or are unable to, se - Paracetamol (acetaminophen) with or without codeine or dihydrocodeine for neuropathic pain in adults
Cochrane Systematic Reviews, 27-Dec-2016
Paracetamol, either alone or in combination with codeine or dihydrocodeine, is commonly used to treat chronic neuropathic pain. This review sought evidence for efficacy and harm from randomised double-blind studies. - Paracetamol for low back pain
Cochrane Systematic Reviews, 6-Jun-2016
Analgesic medication is the most frequently prescribed treatment for low back pain (LBP), of which paracetamol (acetaminophen) is recommended as the first choice medication. However, there is uncertainty about the efficacy of paracetamol for LBP. - Paracetamol for pain relief after surgical removal of lower wisdom teeth
Cochrane Systematic Reviews, 4-Feb-2014
Paracetamol has been commonly used for the relief of postoperative pain following oral surgery. In this review we investigated the optimal dose of paracetamol and the optimal time for drug administration to provide pain relief, taking into account the sid - Paracetamol versus nonsteroidal anti‐inflammatory drugs for rheumatoid arthritis
Cochrane Systematic Reviews, 26-Jan-2004
Nonsteroidal anti-inflammatory drugs (NSAIDs) are usually preferred for simple analgesics such as paracetamol for rheumatoid arthritis. It is not clear, however, whether the trade-offs between benefits and harms of NSAIDs are preferable to those of parace - Paracetamol versus placebo for knee and hip osteoarthritis
Cochrane Systematic Reviews, 25-Feb-2019
Paracetamol (acetaminophen) is vastly recommended as the first-line analgesic for osteoarthritis of the hip or knee. However, there has been controversy about this recommendation given recent studies have revealed small effects of paracetamol when compare
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