- Open versus closed surgical exposure of canine teeth that are displaced in the roof of the mouth
Cochrane Systematic Reviews, 21-Aug-2017
Palatally displaced canines or PDCs are upper permanent canines, commonly known as 'eye' teeth, that are displaced in the roof of the mouth. This can leave unsightly gaps, cause damage to the surrounding roots (which can be so severe that neighbouring tee - Open versus laparoscopic (assisted) ileo pouch anal anastomosis for ulcerative colitis and familial adenomatous polyposis
Cochrane Systematic Reviews, 21-Jan-2009
Restorative proctocolectomy with ileo pouch anal anastomosis (IPAA) is the main surgical treatment for patients with ulcerative colitis (UC) and familial adenomatous polyposis (FAP). With the advancements of minimal-invasive surgery this demanding operati - Open versus laparoscopic pyloromyotomy for pyloric stenosis
Cochrane Systematic Reviews, 9-Mar-2021
Infantile hypertrophic pyloric stenosis (IHPS) is a disorder of young children (aged one year or less) and can be treated by laparoscopic (LP) or open (OP) longitudinal myotomy of the pylorus. Since the first description in 1990, LP is being performed mor - Open, small‐incision, or laparoscopic cholecystectomy for patients with symptomatic cholecystolithiasis. An overview of Cochrane Hepato‐Biliary Group reviews
Cochrane Systematic Reviews, 20-Jan-2010
Patients with symptomatic cholecystolithiasis are treated by three different techniques of cholecystectomy: open, small-incision, or laparoscopic. There is no overview on Cochrane systematic reviews on these three interventions. - Operative and non-operative treatment options for dislocation of the hip following total hip arthroplasty
Cochrane Systematic Reviews, 6-Nov-2008
Dislocation following hip replacement is associated with significant morbidity and functional cost. The cause is usually multifactorial. A variety of treatment options are available which can broadly be classified into operative and non-operative. - Operative caries management in adults and children
Cochrane Systematic Reviews, 24-Jul-2019
The management of dental caries has traditionally involved removal of all soft demineralised dentine before a filling is placed. However, the benefits of complete caries removal have been questioned because of concerns about the possible adverse effects o - Operative procedures for fissure in ano
Cochrane Systematic Reviews, 9-Nov-2011
Reports of direct comparisons between operative techniques for anal fissure are variable in their results. These reports are either subject to selection bias (in non-randomized studies) or observer bias (in all studies) or have inadequate numbers of patie - Operative versus conservative management for 'fetal distress' in labour
Cochrane Systematic Reviews, 13-Jun-2012
Suspected fetal distress usually results in expedited delivery of a baby (often operatively). The potential harm to a mother and baby from operative delivery may not always be justified especially when fetal distress may be misdiagnosed. Even with a corre - Opioid agonist treatment for people who are dependent on pharmaceutical opioids
Cochrane Systematic Reviews, 5-Sep-2022
There are ongoing concerns regarding pharmaceutical opioid-related harms, including overdose and dependence, with an associated increase in treatment demand. People dependent on pharmaceutical opioids appear to differ in important ways from people who use - Opioid antagonists for alcohol dependence
Cochrane Systematic Reviews, 17-Oct-2010
Alcohol dependence belongs to the globally leading health risk factors. Therapeutic success of psychosocial programs for relapse prevention is moderate and could be increased by an adjuvant treatment with the opioid antagonists naltrexone and nalmefene. - Opioid antagonists for smoking cessation
Cochrane Systematic Reviews, 23-May-2013
The reinforcing properties of nicotine may be mediated through release of various neurotransmitters both centrally and systemically. People who smoke report positive effects such as pleasure, arousal, and relaxation as well as relief of negative affect, t - Opioid antagonists under heavy sedation or anaesthesia for opioid withdrawal
Cochrane Systematic Reviews, 20-Jan-2010
Withdrawal (detoxification) is necessary prior to drug-free treatment or as the end point of long-term substitution treatment. - Opioid antagonists with minimal sedation for opioid withdrawal
Cochrane Systematic Reviews, 29-May-2017
Managed withdrawal is a necessary step prior to drug-free treatment or as the endpoint of long-term substitution treatment. - Opioid switching to improve pain relief and drug tolerability
Cochrane Systematic Reviews, 27-Nov-2015
Patients with cancer, and increasingly chronic non-cancer pain frequently require strong opioids for pain relief. Morphine is the first-line strong opioid of choice for these patients. While most achieve adequate analgesia with morphine, a significant min - Opioid therapy for treating rheumatoid arthritis pain
Cochrane Systematic Reviews, 2-Oct-2011
Despite improvements in the management of rheumatoid arthritis (RA), pain control is often inadequate even when inflammation is well controlled. - Opioid treatment for opioid withdrawal in newborn infants
Cochrane Systematic Reviews, 7-Jul-2021
Neonatal abstinence syndrome (NAS) due to opioid withdrawal may result in disruption of the mother-infant relationship, sleep-wake abnormalities, feeding difficulties, weight loss, seizures and neurodevelopmental problems. - Opioids compared to placebo or other treatments for chronic low‐back pain
Cochrane Systematic Reviews, 27-Aug-2013
The use of opioids in the long-term management of chronic low-back pain (CLBP) has increased dramatically. Despite this trend, the benefits and risks of these medications remain unclear. This review is an update of a Cochrane review first published in 200 - Opioids for acute pancreatitis pain
Cochrane Systematic Reviews, 25-Jul-2013
Acute pancreatitis is an acute inflammatory process of the pancreas that may also involve adjacent tissues and/or remote organ systems. Abdominal pain is the main symptom and is usually accompanied by nausea, vomiting and fever. Opoids are commonly used t - Opioids for agitation in dementia
Cochrane Systematic Reviews, 7-May-2015
Agitation is a common experience for people living with dementia, particularly as day-to-day function and cognition start to decline more. At the present time there are limited pharmacological options for relieving agitation and little is known about the - Opioids for cancer pain ‐ an overview of Cochrane reviews
Cochrane Systematic Reviews, 6-Jul-2017
Pain is a common symptom with cancer, and 30% to 50% of all people with cancer will experience moderate to severe pain that can have a major negative impact on their quality of life. Opioid (morphine-like) drugs are commonly used to treat moderate or seve
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