- Oxcarbazepine versus carbamazepine monotherapy for partial onset seizures
Cochrane Systematic Reviews, 11-Aug-2009
Partial onset seizures are often treated with the standard antiepileptic drug carbamazepine. Oxcarbazepine is a newer antiepileptic drug related to carbamazepine that is claimed to be better tolerated. - Oxcarbazepine versus phenytoin monotherapy for epilepsy: an individual participant data review
Cochrane Systematic Reviews, 16-Oct-2018
This is an updated version of the Cochrane Review previously published in 2013. This review is one in a series of Cochrane Reviews investigating pair-wise monotherapy comparisons. - Oximes for acute organophosphate pesticide poisoning
Cochrane Systematic Reviews, 18-Jan-2011
Acute organophosphorus pesticide poisoning causes tens of thousands of deaths each year across the developing world. Standard treatment involves administration of intravenous atropine and oxime to reactivate inhibited acetylcholinesterase. The clinical us - Oxycodone for cancer‐related pain
Cochrane Systematic Reviews, 18-Mar-2019
Many people with cancer experience moderate to severe pain that requires treatment with strong opioids, such as oxycodone and morphine. Strong opioids are, however, not effective for pain in all people, neither are they well-tolerated by all people. The a - Oxycodone for neuropathic pain in adults
Cochrane Systematic Reviews, 28-Jul-2016
This is an update of an earlier review that considered both neuropathic pain and fibromyalgia (Issue 6, 2014), which has now been split into separate reviews for the two conditions. This review considers neuropathic pain only. - Oxycodone for pain in fibromyalgia in adults
Cochrane Systematic Reviews, 1-Sep-2016
This review replaces part of an earlier review that evaluated oxycodone for both neuropathic pain and fibromyalgia, which has now been split into separate reviews for the two conditions. This review will consider pain in fibromyalgia only. - Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen therapy
Cochrane Systematic Reviews, 14-Aug-2017
Breathlessness is a cardinal symptom of chronic obstructive pulmonary disease (COPD). Long-term oxygen therapy (LTOT) is given to improve survival time in people with COPD and severe chronic hypoxaemia at rest. The efficacy of oxygen therapy for breathles - Oxygen targets in the intensive care unit during mechanical ventilation for acute respiratory distress syndrome: a rapid review
Cochrane Systematic Reviews,
Supplemental oxygen is frequently administered to patients with acute respiratory distress syndrome (ARDS), including ARDS secondary to viral illness such as coronavirus disease 19 (COVID-19). An up-to-date understanding of how best to target this therapy - Oxygen therapy during exercise training in chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 11-Jun-2009
Exercise training within the context of pulmonary rehabilitation improves outcomes of exercise capacity, dyspnea and health-related quality of life in individuals with chronic obstructive pulmonary disease (COPD). Supplemental oxygen in comparison to plac - Oxygen therapy for acute myocardial infarction
Cochrane Systematic Reviews, 16-Dec-2016
Oxygen (O2) is widely used in people with acute myocardial infarction (AMI). Previous systematic reviews concluded that there was insufficient evidence to know whether oxygen reduced, increased or had no effect on heart ischaemia or infarct size. Our firs - Oxygen therapy for cystic fibrosis
Cochrane Systematic Reviews, 12-Aug-2013
The most serious complications of cystic fibrosis (CF) relate to respiratory insufficiency. Oxygen supplementation therapy has long been a standard of care for individuals with chronic lung diseases associated with hypoxemia. Physicians commonly prescribe - Oxygen therapy for dyspnoea in adults
Cochrane Systematic Reviews, 20-Nov-2013
Dyspnoea, or distressing breathing, is often a severe subjective symptom in terminal illness and may be difficult to control. Oxygen therapy is currently one of the interventions used to treat it. This review aimed to identify all randomised controlled st - Oxygen therapy for lower respiratory tract infections in children between 3 months and 15 years of age
Cochrane Systematic Reviews, 10-Dec-2014
Treatment for lower respiratory tract infections (LRTIs) includes administering complementary oxygen. The effectiveness of oxygen therapy and of different delivery methods remains uncertain. - Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 13-Jan-2020
Chronic obstructive pulmonary disease (COPD) is a global leading cause of morbidity and mortality, characterised by acute deterioration in symptoms. During these exacerbations, people are prone to developing alveolar hypoventilation, which may be partly c - Oxytocin augmentation of labour in women with epidural analgesia for reducing operative deliveries
Cochrane Systematic Reviews, 11-Jul-2013
The rate of operative deliveries (both caesarean sections, vacuum extractions and forceps), continues to rise throughout the world. These are associated with significant maternal and neonatal morbidity. The most common reasons for operative births in null - Oxytocin for prelabour rupture of membranes at or near term
Cochrane Systematic Reviews, 6-Nov-2008
Induction of labour after prelabour rupture of membranes may reduce the risk of neonatal infection. - Oxytocin for preventing postpartum haemorrhage (PPH) in non-facility birth settings
Cochrane Systematic Reviews, 13-Apr-2016
Postpartum haemorrhage (PPH) is the single leading cause of maternal mortality worldwide. Most of the deaths associated with PPH occur in resource-poor settings where effective methods of prevention and treatment - such as oxytocin - are not accessible be - Oxytocin receptor antagonists for inhibiting preterm labour
Cochrane Systematic Reviews, 2-Jun-2014
Preterm birth, defined as birth between 20 and 36 completed weeks, is a major contributor to perinatal morbidity and mortality globally. Oxytocin receptor antagonists (ORA), such as atosiban, have been specially developed for the treatment of preterm labo - Oxytocin versus no treatment or delayed treatment for slow progress in the first stage of spontaneous labour
Cochrane Systematic Reviews, 18-Jun-2013
Slow progress in the first stage of spontaneous labour is associated with an increased caesarean section rate and fetal and maternal morbidity. Oxytocin has long been advocated as a treatment for slow progress in labour but it is unclear to what extent it - Ozone therapy for the treatment of dental caries
Cochrane Systematic Reviews, 7-Feb-2019
Dental caries is a bacterially mediated disease characterised by demineralisation of the tooth surface, which may lead to cavitation, discomfort, pain and eventual tooth loss. Ozone is toxic to certain bacteria in vitro and it has been suggested that deli
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