- Oral dextrose gel for the treatment of hypoglycaemia in newborn infants
Cochrane Systematic Reviews, 2-May-2016
Neonatal hypoglycaemia, a common condition, can be associated with brain injury. It is frequently managed by providing infants with an alternative source of glucose, given enterally with formula or intravenously with dextrose solution. This often requires - Oral direct thrombin inhibitors or oral factor Xa inhibitors for the treatment of deep vein thrombosis
Cochrane Systematic Reviews, 24-Aug-2015
Deep vein thrombosis (DVT) is a condition in which a clot forms in the deep veins, most commonly of the leg. It occurs in approximately 1 in 1,000 people. If left untreated, the clot can travel up to the lungs and cause a potentially life-threatening pulm - Oral direct thrombin inhibitors or oral factor Xa inhibitors for the treatment of pulmonary embolism
Cochrane Systematic Reviews, 16-Dec-2016
Pulmonary embolism is a potentially life-threatening condition in which a clot can travel from the deep veins, most commonly in the leg, up to the lungs. Previously, a pulmonary embolism was treated with the anticoagulants heparin and vitamin K antagonist - Oral evening primrose oil and borage oil for eczema
Cochrane Systematic Reviews, 26-Feb-2015
Eczema is a chronic inflammatory skin condition, which usually develops in early childhood. Many children outgrow this disorder as they reach secondary school age, and although It may improve with age, there is no cure. Constant itch makes life uncomforta - Oral fumaric acid esters for psoriasis
Cochrane Systematic Reviews, 3-Feb-2017
Psoriasis is a chronic inflammatory skin condition that can markedly reduce life quality. Several systemic therapies exist for moderate to severe psoriasis, including oral fumaric acid esters (FAE). These contain dimethyl fumarate (DMF), the main active i - Oral H1 antihistamines as ‘add-on’ therapy to topical treatment for eczema
Cochrane Systematic Reviews, 15-Jan-2019
The symptoms of eczema can lead to sleeplessness and fatigue and may have a substantial impact on quality of life. Use of oral H1 antihistamines (H1 AH) as adjuvant therapy alongside topical agents is based on the idea that combining the anti-inflammatory - Oral H1 antihistamines as monotherapy for eczema
Cochrane Systematic Reviews, 18-May-2016
Eczema is a common skin disease in many countries, and although the majority of cases of eczema occur before the age of five years and often resolve during childhood or adolescence, it can also persist into adulthood. Itch is the most important aspect of - Oral health education (advice and training) for people with serious mental illness
Cochrane Systematic Reviews, 8-Sep-2016
People with serious mental illness not only experience an erosion of functioning in day-to-day life over a protracted period of time, but evidence also suggests that they have a greater risk of experiencing oral disease and greater oral treatment needs th - Oral health educational interventions for nursing home staff and residents
Cochrane Systematic Reviews, 29-Sep-2016
Associations between nursing home residents’ oral health status and quality of life, respiratory tract infections, and nutritional status have been reported. Educational interventions for nurses or residents, or both, focusing on knowledge and skills rela - Oral herbal therapies for treating osteoarthritis
Cochrane Systematic Reviews, 4-Apr-2016
Medicinal plant products are used orally for treating osteoarthritis. Although their mechanisms of action have not yet been elucidated in full detail, interactions with common inflammatory mediators provide a rationale for using them to treat osteoarthrit - Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia
Cochrane Systematic Reviews, 28-Jul-2017
Ventilator-associated pneumonia (VAP) is defined as pneumonia developing in people who have received mechanical ventilation for at least 48 hours. VAP is a potentially serious complication in these patients who are already critically ill. Oral hygiene car - Oral hygiene interventions for people with intellectual disabilities
Cochrane Systematic Reviews, 3-Jun-2019
Periodontal (gum) disease and dental caries (tooth decay) are the most common causes of tooth loss; dental plaque plays a major role in the development of these diseases. Effective oral hygiene involves removing dental plaque, for example, by regular toot - Oral immunoglobulin for preventing necrotizing enterocolitis in preterm and low birth weight neonates
Cochrane Systematic Reviews, 20-Mar-2017
Necrotizing enterocolitis (NEC) is the most common emergency involving the gastrointestinal tract occurring in the neonatal period. There have been published reports that suggest that oral immunoglobulins (Ig)A and IgG produce an immunoprotective effect i - Oral immunoglobulin for the prevention of rotavirus infection in low birth weight infants
Cochrane Systematic Reviews, 2-Oct-2011
Rotavirus is a common neonatal nosocomial viral infection and epidemics with the newer P(6)G9 strains have been reported. Local mucosal immunity in the intestine to rotavirus is important in the resolution of infection and protection against subsequent in - Oral immunoglobulin for the treatment of rotavirus diarrhea in low birth weight infants
Cochrane Systematic Reviews, 28-Aug-2011
Rotavirus infection is the most common neonatal nosocomial viral infection. It is a major health problem worldwide. Epidemics with the newer P(6)G9 strains have been reported in neonatal units globally. These strains can cause severe symptoms in most infe - Oral immunotherapy for milk allergy
Cochrane Systematic Reviews, 16-Oct-2012
The mainstay of treatment of IgE-mediated cow milk allergy (IMCMA) is an avoidance diet, which is especially difficult with a ubiquitous food like milk. Milk oral immunotherapy (MOIT) may be an alternative treatment, through desensitization or induction o - Oral iron supplements for children in malaria-endemic areas
Cochrane Systematic Reviews, 26-Feb-2016
Iron-deficiency anaemia is common during childhood. Iron administration has been claimed to increase the risk of malaria. - Oral isotretinoin for acne
Cochrane Systematic Reviews, 20-Feb-2019
Acne vulgaris, a chronic inflammatory disease of the pilosebaceous unit associated with socialisation and mental health problems, may affect more than 80% of teenagers. Isotretinoin is widely recognised as a very effective treatment for severe acne; howev - Oral medications including clomiphene citrate or aromatase inhibitors with gonadotropins for controlled ovarian stimulation in women undergoing in vitro fertilisation
Cochrane Systematic Reviews, 2-Nov-2017
Gonadotropins are the most commonly used medications for controlled ovarian stimulation in in vitro fertilisation (IVF). However, they are expensive and invasive, and are associated with the risk of ovarian hyperstimulation syndrome (OHSS). Recent calls f - Oral methylxanthines for bronchiectasis
Cochrane Systematic Reviews, 8-Mar-2010
Bronchiectasis is characterised by chronic sputum production, bronchial wall dilation, recurrent infection and airflow limitation. Methylxanthines are used in the management of airflow limitation associated with asthma and COPD, where they are also purpor
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