- Omega-3 fatty acids for bipolar disorder
Cochrane Systematic Reviews, 2-Nov-2008
Bipolar disorder is a complex psychiatric disorder and is amongst the top thirty causes of worldwide disability. Mood stabilisers are the primary pharmacological intervention, both in the treatment of acute episodes and in prophylaxis. There is, however, - Omega‐3 fatty acids for depression in adults
Cochrane Systematic Reviews,
Major depressive disorder (MDD) is highly debilitating, difficult to treat, has a high rate of recurrence, and negatively impacts the individual and society as a whole. One potential treatment for MDD is n-3 polyunsaturated fatty acids (n-3PUFAs), also kn - Omega‐3 fatty acids for dialysis vascular access outcomes in patients with chronic kidney disease
Cochrane Systematic Reviews, 14-Nov-2018
Maintaining long-term vascular access patency is necessary for high quality haemodialysis (HD) treatment of patients with the terminal and most serious stage of chronic kidney disease (CKD) - end-stage kidney disease (ESKD). Oral supplementation with omeg - Omega-3 fatty acids for intermittent claudication
Cochrane Systematic Reviews, 3-Jul-2013
Omega-3 fatty acids have been used in the treatment and prevention of coronary artery disease although current evidence suggests they may be of limited benefit. Peripheral arterial disease and coronary artery disease share a similar pathogenesis so omega- - Omega‐3 fatty acids for the primary and secondary prevention of cardiovascular disease
Cochrane Systematic Reviews, 19-Feb-2020
Omega-3 polyunsaturated fatty acids from oily fish (long-chain omega-3 (LCn3)), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)), as well as from plants (alpha-linolenic acid (ALA)) may benefit cardiovascular health. Guidelines recomm - Omega‐3 fatty acids for the treatment of dementia
Cochrane Systematic Reviews, 8-Apr-2016
Omega-3 polyunsaturated fatty acids (omega-3 PUFAs) from fish and plant sources are commonly considered as a promising non-medical alternative to improve brain functions and slow down the progression of dementia. This assumption is mostly based on finding - Omega-3 fatty acids supplementation for autism spectrum disorders (ASD)
Cochrane Systematic Reviews, 31-Oct-2011
It has been suggested that impairments associated with autism spectrum disorders (ASD) may be partially explained by deficits of omega-3 fatty acids, and that supplementation of these essential fatty acids may lead to improvement of symptoms. - Omega-3 polyunsaturated fatty acids (PUFA) for type 2 diabetes mellitus
Cochrane Systematic Reviews, 4-Nov-2008
People with type 2 diabetes mellitus are at increased risk from cardiovascular disease. Dietary omega-3 polyunsaturated fatty acids (PUFAs) are known to reduce triglyceride levels, but their impact on cholesterol levels, glycemic control and vascular outc - Omega‐6 fats for the primary and secondary prevention of cardiovascular disease
Cochrane Systematic Reviews, 28-Nov-2018
Omega-6 fats are polyunsaturated fats vital for many physiological functions, but their effect on cardiovascular disease (CVD) risk is debated. - Omentoplasty for oesophagogastrostomy after oesophagectomy
Cochrane Systematic Reviews, 1-Oct-2014
Oesophagectomy followed by oesophagogastrostomy is the preferred treatment for early-stage oesophageal cancer. It carries the risk of anastomotic leakage after oesophagogastric anastomosis, which causes considerable morbidity and mortality and is one of t - Once daily long‐acting beta2‐agonists and long‐acting muscarinic antagonists in a combined inhaler versus placebo for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 4-Mar-2019
Chronic obstructive pulmonary disease (COPD) is a respiratory condition causing accumulation of mucus in the airways, cough, and breathlessness; the disease is progressive and is the fourth most common cause of death worldwide. Current treatment strategie - Once or twice daily versus three times daily amoxicillin with or without clavulanate for the treatment of acute otitis media
Cochrane Systematic Reviews, 9-Sep-2014
Acute otitis media (AOM) is a common problem in children, for which amoxicillin, with or without clavulanate, is frequently prescribed as a treatment of choice. The conventional recommendation is either three or four daily doses. However, nowadays it is f - Once versus twice daily low molecular weight heparin for the initial treatment of venous thromboembolism
Cochrane Systematic Reviews, 1-May-2015
In the initial treatment of venous thromboembolism (VTE) low molecular weight heparin (LMWH) is administered once or twice daily. A once daily treatment regimen is more convenient for the patient and may optimise home treatment. However, it is not clear w - Once‐daily long‐acting beta₂‐agonists/inhaled corticosteroids combined inhalers versus inhaled long‐acting muscarinic antagonists for people with chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 6-Aug-2018
Three classes of inhaler medication are used to manage chronic obstructive pulmonary disease (COPD): long-acting beta2-agonists (LABA); long-acting muscarinic antagonists (LAMA); and inhaled corticosteroids (ICS). To encourage patient adherence, two class - Once‐daily versus multiple‐daily dosing with intravenous aminoglycosides for cystic fibrosis
Cochrane Systematic Reviews, 4-Sep-2019
People with cystic fibrosis, who are chronically colonised with the organism Pseudomonas aeruginosa, often require multiple courses of intravenous aminoglycoside antibiotics for the management of pulmonary exacerbations. The properties of aminoglycosides - Oncoplastic breast‐conserving surgery for women with primary breast cancer
Cochrane Systematic Reviews,
Oncoplastic breast-conserving surgery (O-BCS) involves removing the tumour in the breast and using plastic surgery techniques to reconstruct the breast. The adequacy of published evidence on the safety and efficacy of O-BCS for the treatment of breast can - One dose per day compared to multiple doses per day of gentamicin for treatment of suspected or proven sepsis in neonates
Cochrane Systematic Reviews, 6-Feb-2017
Animal studies and trials in older children and adults suggest that a 'one dose per day' regimen of gentamicin is superior to a 'multiple doses per day' regimen. - One topical fluoride (toothpastes, or mouthrinses, or gels, or varnishes) versus another for preventing dental caries in children and adolescents
Cochrane Systematic Reviews, 28-Aug-2008
Topical fluorides in the form of toothpaste, mouthrinse, varnish and gel are effective caries preventive measures. However, there is uncertainty about the relative value of these interventions. - One‐incision versus two‐incision techniques for arthroscopically assisted anterior cruciate ligament reconstruction in adults
Cochrane Systematic Reviews, 14-Dec-2017
Anterior cruciate ligament (ACL) tears are serious knee injuries that are frequently treated surgically in the form of arthroscopically assisted reconstruction with grafts from the patella or hamstrings tendons. We reviewed the evidence for the choice of - One-to-one dietary interventions undertaken in a dental setting to change dietary behaviour
Cochrane Systematic Reviews, 16-Apr-2012
The dental care setting is an appropriate place to deliver dietary assessment and advice as part of patient management. However, we do not know whether this is effective in changing dietary behaviour.
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