- Biomarkers as point-of-care tests to guide prescription of antibiotics in patients with acute respiratory infections in primary care
Cochrane Systematic Reviews, 3-Nov-2014
Acute respiratory infections (ARIs) are by far the most common reason for prescribing an antibiotic in primary care, even though the majority of ARIs are of viral or non-severe bacterial aetiology. Unnecessary antibiotic use will, in many cases, not be be - Biopsychosocial rehabilitation for upper limb repetitive strain injuries in working age adults
Cochrane Systematic Reviews, 4-Nov-2008
Upper limb repetitive strain injury is a common problem in western countries, causing human suffering and huge economical losses. Patients with prolonged pain associated with repetitive tasks in the work place can face both psychological and physical diff - Bioresorbable fixation devices for musculoskeletal injuries in adults
Cochrane Systematic Reviews, 4-Nov-2008
Bioresorbable implants for musculoskeletal injuries involving bone and ligaments in adults might have significant advantages compared to the conventionally used non-resorbable metal implants because they lead to a gradual transfer of the mechanical load f - Biphasic versus monophasic oral contraceptives for contraception
Cochrane Systematic Reviews, 8-May-2011
Side effects caused by oral contraceptives discourage compliance with, and continuation of, oral contraceptives (OCs). Three approaches have been used to decrease these adverse effects: reduction of steroid dose, development of new steroids, and new formu - Biphasic versus monophasic waveforms for transthoracic defibrillation in out-of-hospital cardiac arrest
Cochrane Systematic Reviews, 5-Feb-2016
Transthoracic defibrillation is a potentially life-saving treatment for people with ventricular fibrillation (VF) and haemodynamically unstable ventricular tachycardia (VT). In recent years, biphasic waveforms have become more commonly used for defibrilla - Biphasic versus triphasic oral contraceptives for contraception
Cochrane Systematic Reviews, 8-May-2011
Side effects caused by oral contraceptives discourage compliance with, and continuation of, oral contraceptives. A suggested disadvantage of biphasic compared to triphasic oral contraceptive (OC) pills is an increase in breakthrough bleeding. We conducted - Bisphosphonate therapy for children and adolescents with secondary osteoporosis
Cochrane Systematic Reviews, 24-May-2010
Children with chronic illnesses are at increased risk for reductions in bone strength and subsequent fractures (osteoporosis), either due to the impact of the underlying condition on skeletal development or due to the osteotoxic effect of medications (e.g - Bisphosphonates for advanced prostate cancer
Cochrane Systematic Reviews, 18-Dec-2017
The prevalence and incidence of pain and skeletal complications of metastatic bone disease such as pathologic fractures, spinal cord compression and hypercalcemia is high and an important contributor to morbidity, poor performance status and decreased qua - Bisphosphonates for osteoporosis in primary biliary cirrhosis
Cochrane Systematic Reviews, 12-Nov-2011
Bisphosphonates are widely used for treatment of postmenopausal osteoporosis. Patients with primary biliary cirrhosis often have osteoporosis - either postmenopausal or secondary to the liver disease. No systematic review or meta-analysis has assessed the - Bisphosphonates for steroid-induced osteoporosis
Cochrane Systematic Reviews, 14-Oct-2016
This is an update of a Cochrane Review first published in 1999. Corticosteroids are widely used in inflammatory conditions as an immunosuppressive agent. Bone loss is a serious side effect of this therapy. Several studies have examined the use of bisphosp - Bisphosphonates for the relief of pain secondary to bone metastases
Cochrane Systematic Reviews, 3-Aug-2017
Bisphosphonates form part of standard therapy for hypercalcemia and the prevention of skeletal events in some cancers. However, the role of bisphosphonates in pain relief for bony metastases remains uncertain. - Black cohosh (Cimicifuga spp.) for menopausal symptoms
Cochrane Systematic Reviews, 13-Sep-2012
Menopause can be a distressing and disruptive time for many women, with many experiencing hot flushes, night sweats, vaginal atrophy and dryness. Postmenopausal women are also at increased risk of osteoporosis. Interventions that decrease the severity and - Blood pressure control for diabetic retinopathy
Cochrane Systematic Reviews, 28-Jan-2015
Diabetic retinopathy is a common complication of diabetes and a leading cause of visual impairment and blindness. Research has established the importance of blood glucose control to prevent development and progression of the ocular complications of diabet - Blood pressure lowering efficacy of beta-1 selective beta blockers for primary hypertension
Cochrane Systematic Reviews, 23-Apr-2016
Beta blockers are commonly used to treat hypertension. The blood pressure reading is the primary tool for physicians and patients to assess the efficacy of the treatment. The blood pressure lowering effect of beta-1 selective blockers is not known. - Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension
Cochrane Systematic Reviews, 3-Mar-2016
Blood pressure is a commonly measured risk factor for non-fatal and fatal cardiovascular adverse events such as heart attacks and strokes. Clinical trials have suggested that coenzyme Q10, a non-prescription nutritional supplement, can effectively lower b - Blood pressure lowering efficacy of diuretics as second-line therapy for primary hypertension
Cochrane Systematic Reviews, 12-Aug-2009
Diuretics are widely prescribed for hypertension not only as a first-line drug but also as a second-line drug. Therefore, it is essential to determine the effects of diuretics on blood pressure (BP), heart rate and withdrawals due to adverse effects (WDAE - Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension
Cochrane Systematic Reviews, 26-Aug-2015
Drugs with combined alpha and beta blocking activity are commonly prescribed to treat hypertension. However, the blood pressure (BP) lowering efficacy of this class of beta blockers has not been systematically reviewed and quantified. - Blood pressure lowering efficacy of nonselective beta-blockers for primary hypertension
Cochrane Systematic Reviews, 28-Feb-2014
Beta-blockers are one of the classes of drugs frequently used to treat hypertension. Quantifying the blood pressure (BP) lowering effects of nonselective beta-blockers provides important information that aids clinical decision making. - Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension
Cochrane Systematic Reviews, 27-Nov-2014
Partial agonists are a subclass of beta blockers used to treat hypertension in many countries. Partial agonist act by stimulating beta receptors when they are quiescent and blocking beta receptors when they are active. The blood pressure (BP) lowering eff - Blood pressure lowering efficacy of renin inhibitors for primary hypertension
Cochrane Systematic Reviews, 20-Apr-2017
Hypertension is a chronic condition associated with an increased risk of mortality and morbidity. Renin is the enzyme responsible for converting angiotensinogen to angiotensin I, which is then converted to angiotensin II. Renin inhibitors are a new class
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