- Environmental and behavioural modifications for improving food and fluid intake in people with dementia
Cochrane Systematic Reviews, 29-Jun-2018
Weight loss, malnutrition and dehydration are common problems for people with dementia. Environmental modifications such as, change of routine, context or ambience at mealtimes, or behavioural modifications, such as education or training of people with de - Enzyme replacement and substrate reduction therapy for Gaucher disease
Cochrane Systematic Reviews, 13-Apr-2015
Gaucher disease, a rare disorder, is caused by inherited deficiency of the enzyme glucocerebrosidase. It is unique among the ultra-orphan disorders in that four treatments are currently approved by various regulatory authorities for use in routine clinica - Enzyme replacement therapy for infantile-onset Pompe disease
Cochrane Systematic Reviews, 14-Dec-2017
Infantile-onset Pompe disease is a rare and progressive autosomal-recessive disorder caused by a deficiency of the lysosomal enzyme acid alpha-glucosidase (GAA). Current treatment involves enzyme replacement therapy (with recombinant human alglucosidase a - Enzyme replacement therapy with galsulfase for mucopolysaccharidosis type VI
Cochrane Systematic Reviews, 25-Feb-2016
Mucopolysaccharidosis type VI or Maroteaux-Lamy syndrome is a rare genetic disorder caused by the deficiency of arylsulphatase B. The resultant accumulation of dermatan sulphate causes lysosomal damage. - Enzyme replacement therapy with laronidase (Aldurazyme®) for treating mucopolysaccharidosis type I
Cochrane Systematic Reviews, 18-Jun-2019
Mucopolysaccharidosis type I can be classified as three clinical sub-types; Hurler syndrome, Hurler-Scheie syndrome and Scheie syndrome, with the scale of severity being such that Hurler syndrome is the most severe and Scheie syndrome the least severe. It - Epidural analgesia for pain relief following hip or knee replacement
Cochrane Systematic Reviews, 30-Jan-2014
Hip and knee replacement are common operative procedures to improve mobility and quality of life. Adequate pain relief is essential in the postoperative period to enable ambulation and initiation of physiotherapy. Lumbar epidural analgesia is a common mod - Epidural blood patching for preventing and treating post-dural puncture headache
Cochrane Systematic Reviews, 22-Nov-2013
This is an update of a Cochrane Review first published in Issue 2, 2002. Dural puncture is a common procedure, but leakage of cerebrospinal fluid (CSF) from the resulting dural defect may cause post-dural puncture headache (PDPH) after the procedure, and - Epidural therapy for the treatment of severe pre-eclampsia in non labouring women
Cochrane Systematic Reviews, 28-Nov-2017
Pre-eclampsia is a pregnancy-specific multi-organ disorder, which is characterised by hypertension and multisystem organ involvement and which has significant maternal and fetal morbidity and mortality. Failure of the placental vascular remodelling and re - Epilepsy clinics versus general neurology or medical clinics
Cochrane Systematic Reviews, 25-Oct-2008
Epilepsy is the most common serious neurological condition after stroke, with a 0.5% prevalence, and a two to three per cent life time risk of being given a diagnosis of epilepsy in the developed world. - Epinephrine for bronchiolitis
Cochrane Systematic Reviews, 2-May-2011
Bronchodilators are commonly used for acute bronchiolitis, despite uncertain effectiveness. - Epinephrine for the resuscitation of apparently stillborn or extremely bradycardic newborn infants
Cochrane Systematic Reviews, 17-Jan-2011
Epinephrine is a cardiac stimulant with complex effects on the heart and blood vessels. It has been used for decades in all age groups to treat cardiac arrest and bradycardia. Despite formal guidelines for the use of epinephrine in neonatal resuscitation, - Epinephrine for transient tachypnea of the newborn
Cochrane Systematic Reviews, 20-May-2016
Transient tachypnea of the newborn is characterized by tachypnea and signs of respiratory distress. Transient tachypnea typically appears within the first two hours of life in term and late preterm newborns. Although transient tachypnea of the newborn is - Epinephrine injection versus epinephrine injection and a second endoscopic method in high-risk bleeding ulcers
Cochrane Systematic Reviews, 9-Oct-2014
Endoscopic therapy reduces the rebleeding rate and the need for surgery in patients with bleeding peptic ulcers. - Eplerenone for hypertension
Cochrane Systematic Reviews, 28-Feb-2017
Eplerenone is an aldosterone receptor blocker that is chemically derived from spironolactone. In Canada, it is indicated for use as adjunctive therapy to reduce mortality for heart failure patients with New York Heart Association (NYHA) class II systolic - Eradication therapy for Burkholderia cepacia complex in people with cystic fibrosis
Cochrane Systematic Reviews, 15-Apr-2019
Chronic infection with Burkholderia cepacia complex species remains a significant problem for clinicians treating people with cystic fibrosis. Colonisation with Burkholderia cepacia complex species is linked to a more rapid decline in lung function and in - Ergonomic and physiotherapeutic interventions for treating work-related complaints of the arm, neck or shoulder in adults
Cochrane Systematic Reviews, 20-Jan-2010
Conservative interventions such as physiotherapy and ergonomic adjustments (such as keyboard adjustments or ergonomic advice) play a major role in the treatment of most work-related complaints of the arm, neck or shoulder (CANS). - Ergonomic positioning or equipment for treating carpal tunnel syndrome
Cochrane Systematic Reviews, 18-Jan-2012
Non-surgical treatment, including ergonomic positioning or equipment, are sometimes offered to people experiencing mild to moderate symptoms from carpal tunnel syndrome (CTS). The effectiveness and duration of benefit from ergonomic positioning or equipme - Erythromycin for the prevention and treatment of feeding intolerance in preterm infants
Cochrane Systematic Reviews, 8-May-2008
Functional immaturity of gastrointestinal motility predisposes preterm infants to feeding intolerance. Erythromycin is a motilin agonist that exerts its prokinetic effect by stimulating propagative contractile activity in the interdigestive phase. - Erythromycin for the prevention of chronic lung disease in intubated preterm infants at risk for, or colonized or infected with Ureaplasma urealyticum
Cochrane Systematic Reviews, 22-Oct-2008
Controversy exists over whether or not Ureaplasma urealyticum colonization or infection of the respiratory tract contributes to the severity of chronic lung disease (CLD), a major cause of morbidity and mortality in preterm infants. - Erythropoiesis-stimulating agents for anaemia in adults with chronic kidney disease: a network meta-analysis
Cochrane Systematic Reviews, 3-Dec-2014
Several erythropoiesis-stimulating agents (ESAs) are available for treating anaemia in people with chronic kidney disease (CKD). Their relative efficacy (preventing blood transfusions and reducing fatigue and breathlessness) and safety (mortality and card
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