- Corticosteroids for preventing relapse following acute exacerbations of asthma
Cochrane Systematic Reviews, 22-Jul-2008
Acute asthma is responsible for many emergency department (ED) visits annually. Between 12 to 16% will relapse to require additional interventions within two weeks of ED discharge. Treatment of acute asthma is based on rapid reversal of bronchospasm and r - Corticosteroids for pulmonary sarcoidosis
Cochrane Systematic Reviews, 23-Mar-2010
Pulmonary sarcoidosis is a common condition with an unpredictable course. Oral (OCS) or inhaled steroids (ICS) are widely used in its treatment, but there is no consensus about when and in whom therapy should be initiated, what dose should be given and fo - Corticosteroids for septic arthritis in children
Cochrane Systematic Reviews, 21-Nov-2018
Septic arthritis is an acute infection of the joints characterised by erosive disruption of the articular space. It is the most common non-degenerative articular disease in developing countries. The most vulnerable population for septic arthritis includes - Corticosteroids for the management of cancer-related pain in adults
Cochrane Systematic Reviews, 30-Apr-2015
One of the most feared symptoms associated with cancer is pain. Opioids remain the mainstay of pain treatment but corticosteroids are often used concurrently as co- or adjuvant analgesics. Due to their anti-inflammatory mechanism of action, corticosteroid - Corticosteroids for the treatment of Duchenne muscular dystrophy
Cochrane Systematic Reviews, 14-Jun-2016
Duchenne muscular dystrophy (DMD) is the most common muscular dystrophy of childhood. Untreated, this incurable disease, which has an X-linked recessive inheritance, is characterised by muscle wasting and loss of walking ability, leading to complete wheel - Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis)
Cochrane Systematic Reviews, 5-Apr-2011
Idiopathic acute vestibular dysfunction (vestibular neuritis) is the second most common cause of peripheral vertigo after benign paroxysmal positional vertigo (BPPV) and accounts for 7% of the patients who present at outpatient clinics specialising in the - Corticosteroids for the treatment of Kawasaki disease in children
Cochrane Systematic Reviews, 27-Jan-2017
Kawasaki disease (KD), or mucocutaneous syndrome, is the leading cause of childhood-acquired heart disease in the developed world. There is much controversy on how best to treat children with KD and in particular who may benefit from additional treatment - Corticosteroids for treating nerve damage in leprosy
Cochrane Systematic Reviews, 21-Mar-2017
Leprosy causes nerve damage that can result in nerve function impairment and disability. Corticosteroids are commonly used for treating nerve damage, although their long-term effect is uncertain. This is an update of a review first published in 2007, and - Corticosteroids for viral myocarditis
Cochrane Systematic Reviews, 17-Oct-2013
Myocarditis is defined as inflammation of the myocardium accompanied by myocellular necrosis. Experimental evidence suggests that autoimmune mechanisms follow viral infection, resulting in inflammation and necrosis in the myocardium. However, the use of c - Corticosteroids or ACTH for acute exacerbations in multiple sclerosis
Cochrane Systematic Reviews, 12-Nov-2013
Corticosteroids are commonly used to improve the rate of recovery from acute exacerbation in multiple sclerosis (MS) patients. However, it is unclear just how effective these agents are and which is the best treatment schedule (type of drug, dose, frequen - Cot-nursing versus incubator care for preterm infants
Cochrane Systematic Reviews, 13-Jun-2011
Preterm infants are usually nursed in incubators, but cot-nursing may provide an alternative. While there may be benefits of nursing preterm infants in open cots, there may be potential risks such as nosocomial infection caused by more handling due to eas - Couple therapy for depression
Cochrane Systematic Reviews, 8-Jun-2018
Couple therapy for depression has the twofold aim of modifying negative interaction patterns and increasing mutually supportive aspects of intimate relationships, changing the interpersonal context of depression. Couple therapy is included in several guid - Covering ileo- or colostomy in anterior resection for rectal carcinoma
Cochrane Systematic Reviews, 11-Apr-2010
Anastomotic leakage is one of the most important complications that occur after surgical low anterior resection for rectal cancer. There are indications that anastomotic leak is associated with increased morbidity, mortality, frequent re-operation or radi - Cow's milk protein avoidance and development of childhood wheeze in children with a family history of atopy
Cochrane Systematic Reviews, 10-Sep-2008
In infants with a family history of atopy, food allergen avoidance has been advocated as means of preventing the development of atopic disease, when breast-feeding is not possible or supplemental feeding is needed. Most infant formulas are based on cow's - Cranial irradiation for preventing brain metastases of small cell lung cancer in patients in complete remission
Cochrane Systematic Reviews, 6-Feb-2018
Prophylactic cranial irradiation halves the rate of brain metastases in patients with small cell lung cancer. Individual randomized trials conducted on patients in complete remission were unable to clarify whether this treatment improves survival. - C-reactive protein for diagnosing late-onset infection in newborn infants
Cochrane Systematic Reviews, 11-Feb-2019
Late-onset infection is the most common serious complication associated with hospital care for newborn infants. Because confirming the diagnosis by microbiological culture typically takes 24 to 48 hours, the serum level of the inflammatory marker C-reacti - Creatine and creatine analogues in hypertension and cardiovascular disease
Cochrane Systematic Reviews, 21-Sep-2011
The creatine kinase system, the central regulatory system of cellular energy metabolism, provides ATP in situ at ATP-ases involved in ion transport and muscle contraction. Furthermore, the enzyme system provides relative protection from tissue ischaemia a - Creatine for amyotrophic lateral sclerosis/motor neuron disease
Cochrane Systematic Reviews, 14-Nov-2012
Creatine, a naturally-occurring nitrogenous organic acid involved in adenosine triphosphate (ATP) production, has been shown to increase survival in mouse models of amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND). Results fro - Creatine for Parkinson's disease
Cochrane Systematic Reviews, 16-Jun-2014
Parkinson's disease is one of the most common neurodegenerative disorders and mitochondrial dysfunction plays an important role in its pathogenesis. Creatine is effective in improving mitochondrial function. It may therefore be useful for slowing the prog - Creatine for women in pregnancy for neuroprotection of the fetus
Cochrane Systematic Reviews, 16-Dec-2014
Creatine is an amino acid derivative and, when phosphorylated (phosphocreatine), is involved in replenishing adenosine triphosphate (ATP) via the creatine kinase reaction. Cells obtain creatine from a diet rich in fish, meat, or dairy and by endogenous sy
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