- Near‐infrared spectroscopy for fetal assessment during labour
Cochrane Systematic Reviews, 24-Jul-2000
Over the past four decades, continuous electronic fetal monitoring (EFM) has been increasingly employed to detect fetal acidaemia in labour, with a view toward prevention of hypoxic ischaemic encephalopathy, permanent neurologic injury, and death. Althoug - Nebulised deoxyribonuclease for viral bronchiolitis in children younger than 24 months
Cochrane Systematic Reviews, 9-Oct-2012
Bronchiolitis is one of the most common respiratory problems in the first year of life. The sputum of infants with bronchiolitis has increased deoxyribonucleic acid (DNA) content, leading to mucous plugging and airway obstruction. Recombinant human deoxyr - Nebulised hypertonic saline for cystic fibrosis
Cochrane Systematic Reviews, 27-Sep-2018
Impaired mucociliary clearance characterises lung disease in cystic fibrosis (CF). Hypertonic saline enhances mucociliary clearance and may lessen the destructive inflammatory process in the airways. This is an update of a previously published review. - Nebulised hypertonic saline solution for acute bronchiolitis in infants
Cochrane Systematic Reviews, 21-Dec-2017
Airway oedema (swelling) and mucus plugging are the principal pathological features in infants with acute viral bronchiolitis. Nebulised hypertonic saline solution (= 3%) may reduce these pathological changes and decrease airway obstruction. This is an up - Nebulised morphine for severe interstitial lung disease
Cochrane Systematic Reviews, 22-Jul-2002
The evidence to support the use of nebulized morphine to improve dyspnoea and exercise limitation in terminally ill patients with chronic lung disease is conflicting. - Nebulised surfactant in preterm infants with or at risk of respiratory distress syndrome
Cochrane Systematic Reviews, 11-Sep-2012
Nebulised surfactant has the potential to deliver surfactant to the infant lung with the goal of avoiding endotracheal intubation and ventilation, ventilator-induced lung injury and bronchopulmonary dysplasia (BPD). - Nebuliser systems for drug delivery in cystic fibrosis
Cochrane Systematic Reviews, 27-Mar-2013
Nebuliser systems are used to deliver medications to control the symptoms and the progression of lung disease in people with cystic fibrosis. Many types of nebuliser systems are available for use with various medications; however, there has been no previo - Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis
Cochrane Systematic Reviews, 12-Jul-2013
Cystic fibrosis is an inherited condition resulting in thickened, sticky respiratory secretions. Respiratory failure, due to recurrent pulmonary infection and inflammation, is the most common cause of mortality. Muco-active therapies (e.g. dornase alfa an - Nebulized epinephrine for croup in children
Cochrane Systematic Reviews, 2-Oct-2013
Croup is a common childhood illness characterized by barky cough, stridor, hoarseness and respiratory distress. Children with severe croup are at risk for intubation. Nebulized epinephrine may prevent intubation. - Nebulized racemic epinephrine for extubation of newborn infants
Cochrane Systematic Reviews, 21-Jan-2002
Following a period of mechanical ventilation, post-extubation upper airway obstruction can occur in newborn infants, especially after prolonged, traumatic or multiple intubations. The subsequent increase in upper airway resistance may lead to respiratory - Nedocromil sodium for chronic asthma in children
Cochrane Systematic Reviews, 19-Jul-2006
Currently inhaled corticosteroids are the main stay in the maintenance treatment of chronic asthma in children. Although inhaled corticosteroids play a crucial role in the management of childhood asthma, the long-term side effects of inhaled corticosteroi - Nedocromil sodium for preventing exercise‐induced bronchoconstriction
Cochrane Systematic Reviews, 21-Jan-2002
Exercise-induced bronchoconstriction (EIB) following strenuous physical exertion afflicts many people. It can be the cause of sub-optimal performance, symptoms such as cough, dyspnea, wheeze and chest tightness, and can lead people to avoid physical activ - Nedocromil sodium versus sodium cromoglycate for preventing exercise‐induced bronchoconstriction
Cochrane Systematic Reviews, 24-Jul-2000
Nedocromil sodium and sodium cromoglycate inhaled shortly before exercise appear to reduce the severity of exercise-induced bronchoconstriction. There is some debate over which drug may be more effective. - Needle aspiration versus incision and drainage for the treatment of peritonsillar abscess
Cochrane Systematic Reviews, 23-Dec-2016
Peritonsillar abscess is a common infection presenting as a collection of pus in the peritonsillar area. The condition is characterised by a severe sore throat, difficulty in swallowing and pain on swallowing, fever and malaise, and trismus. Needle aspira - Needle aspiration versus intercostal tube drainage for pneumothorax in the newborn
Cochrane Systematic Reviews, 1-Feb-2019
Pneumothorax occurs more frequently in the neonatal period than at any other time of life and is associated with increased mortality and morbidity. It can be treated with either aspiration with a syringe (using a needle or an angiocatheter) or a chest tub - Needle gauge and tip designs for preventing post‐dural puncture headache (PDPH)
Cochrane Systematic Reviews, 7-Apr-2017
Post-dural puncture headache (PDPH) is one of the most common complications of diagnostic and therapeutic lumbar punctures. PDPH is defined as any headache occurring after a lumbar puncture that worsens within 15 minutes of sitting or standing and is reli - Needle size for vaccination procedures in children and adolescents
Cochrane Systematic Reviews, 9-Aug-2018
This is an update of a Cochrane Review first published in 2015. The conclusions have not changed. - Needle syringe programmes and opioid substitution therapy for preventing hepatitis C transmission in people who inject drugs
Cochrane Systematic Reviews, 18-Sep-2017
Needle syringe programmes and opioid substitution therapy for preventing hepatitis C transmission in people who inject drugs - Needling for encapsulated trabeculectomy filtering blebs
Cochrane Systematic Reviews, 15-Aug-2012
Encapsulation of a filtering bleb following trabeculectomy may lead to elevation of intraocular pressure, prompting further medical or surgical intervention. It has been suggested that needling of an encapsulated bleb may be effective in re-establishing d - Negative pressure wound therapy for managing the open abdomen in non‐trauma patients
Cochrane Systematic Reviews, 6-May-2022
Management of the open abdomen is a considerable burden for patients and healthcare professionals. Various temporary abdominal closure techniques have been suggested for managing the open abdomen. In recent years, negative pressure wound therapy (NPWT) ha
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