- Nebulised hypertonic saline solution for acute bronchiolitis in infants
Cochrane Systematic Reviews, 5-Dec-2017
Airway oedema (swelling) and mucus plugging are the principal pathological features in infants with acute viral bronchiolitis. Nebulised hypertonic saline solution (= 3%) may reduce these pathological changes and decrease airway obstruction. This is an up - Nebulised morphine for severe interstitial lung disease
Cochrane Systematic Reviews, 1-Jun-2011
The evidence to support the use of nebulized morphine to improve dyspnoea and exercise limitation in terminally ill patients with chronic lung disease is conflicting. - Nebulised surfactant in preterm infants with or at risk of respiratory distress syndrome
Cochrane Systematic Reviews, 11-Sep-2012
Nebulised surfactant has the potential to deliver surfactant to the infant lung with the goal of avoiding endotracheal intubation and ventilation, ventilator-induced lung injury and bronchopulmonary dysplasia (BPD). - Nebuliser systems for drug delivery in cystic fibrosis
Cochrane Systematic Reviews, 27-Mar-2013
Nebuliser systems are used to deliver medications to control the symptoms and the progression of lung disease in people with cystic fibrosis. Many types of nebuliser systems are available for use with various medications; however, there has been no previo - Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis
Cochrane Systematic Reviews, 13-Apr-2015
Cystic fibrosis is an inherited condition resulting in thickened, sticky respiratory secretions. Respiratory failure, due to recurrent pulmonary infection and inflammation, is the most common cause of mortality. Muco-active therapies (e.g. dornase alfa an - Nebulized epinephrine for croup in children
Cochrane Systematic Reviews, 2-Oct-2013
Croup is a common childhood illness characterized by barky cough, stridor, hoarseness and respiratory distress. Children with severe croup are at risk for intubation. Nebulized epinephrine may prevent intubation. - Nebulized racemic epinephrine for extubation of newborn infants
Cochrane Systematic Reviews, 29-Mar-2010
Following a period of mechanical ventilation, post-extubation upper airway obstruction can occur in newborn infants, especially after prolonged, traumatic or multiple intubations. The subsequent increase in upper airway resistance may lead to respiratory - Nedocromil sodium for chronic asthma in children
Cochrane Systematic Reviews, 9-Nov-2009
Currently inhaled corticosteroids are the main stay in the maintenance treatment of chronic asthma in children. Although inhaled corticosteroids play a crucial role in the management of childhood asthma, the long-term side effects of inhaled corticosteroi - Nedocromil sodium for preventing exercise-induced bronchoconstriction
Cochrane Systematic Reviews, 29-Mar-2009
Exercise-induced bronchoconstriction (EIB) following strenuous physical exertion afflicts many people. It can be the cause of sub-optimal performance, symptoms such as cough, dyspnea, wheeze and chest tightness, and can lead people to avoid physical activ - Nedocromil sodium versus sodium cromoglycate for preventing exercise-induced bronchoconstriction
Cochrane Systematic Reviews, 12-Aug-2008
Nedocromil sodium and sodium cromoglycate inhaled shortly before exercise appear to reduce the severity of exercise-induced bronchoconstriction. There is some debate over which drug may be more effective. - Needle aspiration versus incision and drainage for the treatment of peritonsillar abscess
Cochrane Systematic Reviews, 22-Dec-2016
Peritonsillar abscess is a common infection presenting as a collection of pus in the peritonsillar area. The condition is characterised by a severe sore throat, difficulty in swallowing and pain on swallowing, fever and malaise, and trismus. Needle aspira - Needle aspiration versus intercostal tube drainage for pneumothorax in the newborn
Cochrane Systematic Reviews, 31-Jan-2019
Pneumothorax occurs more frequently in the neonatal period than at any other time of life and is associated with increased mortality and morbidity. It can be treated with either aspiration with a syringe (using a needle or an angiocatheter) or a chest tub - Needle gauge and tip designs for preventing post-dural puncture headache (PDPH)
Cochrane Systematic Reviews, 21-Dec-2017
Post-dural puncture headache (PDPH) is one of the most common complications of diagnostic and therapeutic lumbar punctures. PDPH is defined as any headache occurring after a lumbar puncture that worsens within 15 minutes of sitting or standing and is reli - Needle size for vaccination procedures in children and adolescents
Cochrane Systematic Reviews, 30-Jul-2018
This is an update of a Cochrane Review first published in 2015. The conclusions have not changed. - Needle syringe programmes and opioid substitution therapy for preventing hepatitis C transmission in people who inject drugs
Cochrane Systematic Reviews, 14-Sep-2017
Needle syringe programmes and opioid substitution therapy for preventing hepatitis C transmission in people who inject drugs - Needling for encapsulated trabeculectomy filtering blebs
Cochrane Systematic Reviews, 25-Jun-2012
Encapsulation of a filtering bleb following trabeculectomy may lead to elevation of intraocular pressure, prompting further medical or surgical intervention. It has been suggested that needling of an encapsulated bleb may be effective in re-establishing d - Negative pressure wound therapy for open traumatic wounds
Cochrane Systematic Reviews, 3-Jul-2018
Traumatic wounds (wounds caused by injury) range from abrasions and minor skin incisions or tears, to wounds with extensive tissue damage or loss as well as damage to bone and internal organs. Two key types of traumatic wounds considered in this review ar - Negative pressure wound therapy for partial-thickness burns
Cochrane Systematic Reviews, 11-Dec-2014
A burn wound is a complex and evolving injury, with both local and systemic consequences. Burn treatments include a variety of dressings, as well as newer strategies, such as negative pressure wound therapy (NPWT), which, by means of a suction force that - Negative pressure wound therapy for surgical wounds healing by primary closure
Cochrane Systematic Reviews, 20-Mar-2019
Indications for the use of negative pressure wound therapy (NPWT) are broad and include prophylaxis for surgical site infections (SSIs). While existing evidence for the effectiveness of NPWT remains uncertain, new trials necessitated an updated review of - Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus
Cochrane Systematic Reviews, 16-Oct-2018
Foot wounds in people with diabetes mellitus (DM) are a common and serious global health issue. People with DM are prone to developing foot ulcers and, if these do not heal, they may also undergo foot amputation surgery resulting in postoperative wounds.
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