- Antibiotics and antiseptics for venous leg ulcers
Cochrane Systematic Reviews, 9-Jan-2014
Venous leg ulcers are a type of chronic wound affecting up to 1% of adults in developed countries at some point during their lives. Many of these wounds are colonised by bacteria or show signs of clinical infection. The presence of infection may delay ulc - Antibiotics at the time of removal of central venous catheter to reduce morbidity and mortality in newborn infants
Cochrane Systematic Reviews, 7-Mar-2018
Late-onset sepsis is associated with increased rates of mortality and morbidity in newborn infants, in addition to poorer long-term developmental outcomes and increased length of stay and hospital costs. Central line-associated blood stream infection (CLA - Antibiotics for acute bronchitis
Cochrane Systematic Reviews, 19-Jun-2017
The benefits and risks of antibiotics for acute bronchitis remain unclear despite it being one of the most common illnesses seen in primary care. - Antibiotics for acute laryngitis in adults
Cochrane Systematic Reviews, 23-May-2015
This is an update of the original review published in 2005. Acute laryngitis is a common illness worldwide. Diagnosis is often made by case history alone and treatment often targets symptoms. - Antibiotics for acute maxillary sinusitis in adults
Cochrane Systematic Reviews, 15-Oct-2015
Sinusitis is one of the most common diagnoses among adults in ambulatory care, accounting for 15% to 21% of all adult outpatient antibiotic prescriptions. However, the role of antibiotics for sinusitis is controversial. - Antibiotics for acute otitis media in children
Cochrane Systematic Reviews, 23-Jun-2015
Acute otitis media (AOM) is one of the most common diseases in early infancy and childhood. Antibiotic use for AOM varies from 56% in the Netherlands to 95% in the USA, Canada and Australia. This is an update of a Cochrane review first published in The Co - Antibiotics for acute pyelonephritis in children
Cochrane Systematic Reviews, 25-Jul-2014
Urinary tract infection (UTI) is one of the most common bacterial infections in infants. The most severe form of UTI is acute pyelonephritis, which results in significant acute morbidity and may cause permanent kidney damage. There remains uncertainty reg - Antibiotics for acute rhinosinusitis in adults
Cochrane Systematic Reviews, 10-Sep-2018
Acute rhinosinusitis is an acute infection of the nasal passages and paranasal sinuses that lasts less than four weeks. Diagnosis of acute rhinosinusitis is generally based on clinical signs and symptoms in ambulatory care settings. Technical investigatio - Antibiotics for asymptomatic bacteriuria
Cochrane Systematic Reviews, 8-Apr-2015
Asymptomatic bacteriuria is commonly detected in women aged up to 60 years, patients with diabetes, and the elderly. The benefit of antibiotic treatment for this condition is controversial. - Antibiotics for asymptomatic bacteriuria in kidney transplant recipients
Cochrane Systematic Reviews, 1-Feb-2018
Asymptomatic bacteriuria, defined as bacteriuria without signs or symptoms of urinary tract infection (UTI), occurs in 17% to 51% of kidney transplant recipients and is thought to increase the risk for a subsequent UTI. No consensus exists on the role of - Antibiotics for asymptomatic bacteriuria in pregnancy
Cochrane Systematic Reviews, 25-Nov-2019
Asymptomatic bacteriuria is a bacterial infection of the urine without any of the typical symptoms that are associated with a urinary infection, and occurs in 2% to 15% of pregnancies. If left untreated, up to 30% of mothers will develop acute pyelonephri - Antibiotics for brain abscesses in people with cyanotic congenital heart disease
Cochrane Systematic Reviews, 28-Mar-2013
Brain abscess is a focal, intracerebral infection that begins as a localized area of brain infection and develops into a collection of pus surrounded by a well-vascularized capsule. People with cyanotic congenital heart disease are at risk of developing b - Antibiotics for bronchiolitis in children under two years of age
Cochrane Systematic Reviews, 9-Oct-2014
Bronchiolitis is a serious, potentially life-threatening respiratory illness commonly affecting babies. It is often caused by respiratory syncytial virus (RSV). Antibiotics are not recommended for bronchiolitis unless there is concern about complications - Antibiotics for chronic pulmonary infection in children with a neurodisability (neurodevelopmental disorder)
Cochrane Systematic Reviews, 9-Feb-2023
'Neurodisability' refers to a group of conditions that result primarily from a neurological problem (e.g. cerebral palsy), neuromuscular problem (e.g. a muscular dystrophy) or developmental problems (e.g. developmental impairment, Down syndrome). Children - Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children
Cochrane Systematic Reviews, 4-Jan-2015
Mycoplasma pneumoniae (M. pneumoniae) is widely recognised as an important cause of community-acquired lower respiratory tract infection (LRTI) in children. Pulmonary manifestations are typically tracheobronchitis or pneumonia but M. pneumoniae is also i - Antibiotics for community‐acquired pneumonia in adult outpatients
Cochrane Systematic Reviews, 9-Oct-2014
Lower respiratory tract infection (LRTI) is the third leading cause of death worldwide and the first leading cause of death in low-income countries. Community-acquired pneumonia (CAP) is a common condition that causes a significant disease burden for the - Antibiotics for community‐acquired pneumonia in children
Cochrane Systematic Reviews, 4-Jun-2013
Pneumonia caused by bacterial pathogens is the leading cause of mortality in children in low-income countries. Early administration of antibiotics improves outcomes. - Antibiotics for exacerbations of asthma
Cochrane Systematic Reviews, 25-Jun-2018
Asthma is a chronic respiratory condition that affects over 300 million adults and children worldwide. It is characterised by wheeze, cough, chest tightness, and shortness of breath. Symptoms typically are intermittent and may worsen over a short time, le - Antibiotics for exacerbations of chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 29-Oct-2018
Many patients with an exacerbation of chronic obstructive pulmonary disease (COPD) are treated with antibiotics. However, the value of antibiotics remains uncertain, as systematic reviews and clinical trials have shown conflicting results. - Antibiotics for gonorrhoea in pregnancy
Cochrane Systematic Reviews, 27-Jun-2014
Neisseria gonorrhoeae can be transmitted from the mother's genital tract to the newborn during birth and can cause gonococcal ophthalmia neonatorum as well as systemic neonatal infection. It can also cause endometritis and pelvic sepsis in the mother.
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