- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Early neonatal hyperglycemia is common among very low birth weight (VLBW) neonates. Increased risks for death and major morbidities have been observed among VLBW neonates who develop hyperglycemia. It is uncertain whether the hyperglycemia per se is a cau - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Standard treatment for high grade glioma (HGG) usually entails surgery (either biopsy or resection) followed by radiotherapy plus or minus temozolomide. Implanting wafers impregnated with chemotherapy agents into the resection cavity represents a novel me - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Acute diarrhoea is one of the principal causes of morbidity and mortality among children in low-income countries. The cornerstone of treatment is oral rehydration therapy and dietary management. However, there is a lack of data and studies on both the t - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This is an updated version of the Cochrane Review previously published in 2018. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This is the second update of the review first published in the Cochrane Library (2010, Issue 2) and later updated (2014, Issue 9). - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This is an update of the original Cochrane Review published in Cochrane Library, Issue 10, 2012. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Vaginal dilation therapy is advocated after pelvic radiotherapy to prevent stenosis (abnormal narrowing of the vagina), but can be uncomfortable and psychologically distressing. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Tests for thrombophilia are being performed on a large scale in people after venous thromboembolism (VTE) even though the benefits of testing are still subject to debate. The most important benefit would be a reduction in the risk of recurrent VTE due to - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
A variety of in-service emergency care training courses are currently being promoted as a strategy to improve the quality of care provided to seriously ill newborns and children in low-income countries. Most courses have been developed in high-income coun - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Adjuvant tamoxifen reduces the risk of breast cancer recurrence in women with oestrogen receptor-positive breast cancer. Tamoxifen also increases the risk of postmenopausal bleeding, endometrial polyps, hyperplasia, and endometrial cancer. The levonorgest - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Obstructive sleep apnoea (OSA) is characterised by partial or complete upper airway obstruction during sleep. Approximately 1% to 4% of children are affected by OSA, with adenotonsillar hypertrophy being the most common underlying risk factor. Surgical re - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This review updates part of an earlier Cochrane Review titled "Pregabalin for acute and chronic pain in adults", and considers only neuropathic pain (pain from damage to nervous tissue). Antiepileptic drugs have long been used in pain management. Pregabal - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Breast-conserving therapy for women with breast cancer consists of local excision of the tumour (achieving clear margins) followed by radiotherapy (RT). RT is given to sterilize tumour cells that may remain after surgery to decrease the risk of local tumo - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Tobacco use is estimated to kill 7 million people a year. Nicotine is highly addictive, but surveys indicate that almost 70% of US and UK smokers would like to stop smoking. Although many smokers attempt to give up on their own, advice from a health profe - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Maternal nutrition during pregnancy is known to have an effect on fetal growth and development. It is recommended that women increase their calcium intake during pregnancy and lactation, although the recommended dosage varies among professionals. Currentl - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Postoperative pain may lead to adverse effects on the body, which might result in an increase in morbidity. Its management therefore poses a unique challenge for the clinician. Major shoulder surgery is associated with severe postoperative pain, and diffe - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Severe sepsis and septic shock have recently emerged as particularly acute and lethal challenges amongst critically ill patients presenting to the emergency department (ED). There are no existing data on the current practices of management of patients wit - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Basal cell carcinoma (BCC) is the commonest skin cancer in the white population. It is traditionally treated by surgical excision (SE) or by Mohs micrographic surgery (MMS). - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Liver metastases are often the dominant site of metastatic disease in colorectal cancer. Selective internal radiation therapy (SIRT) involves embolising radiolabeled spheres (SIR-Spheres) into the arterial supply of the liver with the aim of improving the - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Epidermal growth factor receptor (EGFR) inhibitors prevent cell growth and have shown benefit in the treatment of metastatic colorectal cancer, whether used as single agents or in combination with chemotherapy. Clear benefit has been shown in trials of EG
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