- Light-emitting diode phototherapy for unconjugated hyperbilirubinaemia in neonates
Cochrane Systematic Reviews, 8-Nov-2011
Phototherapy is the mainstay of treatment of neonatal hyperbilirubinaemia. The commonly used light sources for providing phototherapy are special blue fluorescent tubes, compact fluorescent tubes and halogen spotlights. However, light emitting diodes (LED - Limited (information only) patient education programs for adults with asthma
Cochrane Systematic Reviews, 21-Jan-2002
A key component of many asthma management guidelines is the recommendation for patient education and regular medical review. A number of controlled trials have been conducted to measure the effectiveness of asthma education programmes. These programmes im - Limited versus full sternotomy for aortic valve replacement
Cochrane Systematic Reviews, 10-Apr-2017
Aortic valve disease is a common condition that is easily treatable with cardiac surgery. This is conventionally performed by opening the sternum longitudinally down the centre ("median sternotomy") and replacing the valve under cardiopulmonary bypass. Me - Linezolid for drug‐resistant pulmonary tuberculosis
Cochrane Systematic Reviews, 20-Mar-2019
Linezolid was recently re-classified as a Group A drug by the World Health Organization (WHO) for treatment of multi-drug resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB), suggesting that it should be included in the re - Linezolid versus vancomycin for skin and soft tissue infections
Cochrane Systematic Reviews, 7-Jan-2016
The morbidity and treatment costs associated with skin and soft tissue infections (SSTIs) are high. Linezolid and vancomycin are antibiotics that are commonly used in treating skin and soft-tissue infections, specifically those infections due to methicill - Lipid emulsions for parenterally fed preterm infants
Cochrane Systematic Reviews, 4-Jun-2019
Conventionally used soybean oil-based lipid emulsion (S-LE) have high polyunsaturated fatty acid (PUFA) content and phytosterols that may contribute to adverse effects in preterm infants. The newer lipid emulsions (LE) from different lipid sources are cur - Lipid emulsions for parenterally fed term and late preterm infants
Cochrane Systematic Reviews, 4-Jun-2019
Lipid emulsions (LE) form a vital component of infant nutrition for critically ill, late preterm or term infants, particularly for those with gastrointestinal failure. Conventionally used soybean oil-based LE (S-LE) have high polyunsaturated fatty acid (P - Lipid‐based nutrient supplements for maternal, birth, and infant developmental outcomes
Cochrane Systematic Reviews, 31-Aug-2018
Ready-to-use lipid-based nutrient supplements (LNS) are a highly nutrient-dense supplement, which could be a good source of macro- and micronutrients for pregnant women who need to supplement their nutrient intake. - Lipid-lowering agents for nephrotic syndrome
Cochrane Systematic Reviews, 11-Nov-2013
Nephrotic syndrome is the collective name given to a group of symptoms that include proteinuria, lipiduria, hypoalbuminaemia, oedema, hypercholesterolaemia, elevated triglycerides, and hyperlipidaemia. Hyperlipidaemia is thought to aggravate glomeruloscle - Lipid‐lowering for peripheral arterial disease of the lower limb
Cochrane Systematic Reviews, 17-Oct-2007
Lipid-lowering therapy is recommended for secondary prevention in people with coronary artery disease. It may also reduce cardiovascular events and/or local disease progression in people with lower limb peripheral arterial disease (PAD). - Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain
Cochrane Systematic Reviews, 1-Feb-2017
Despite multi-modal analgesic techniques, acute postoperative pain remains an unmet health need, with up to three quarters of people undergoing surgery reporting significant pain. Liposomal bupivacaine is an analgesic consisting of bupivacaine hydrochlori - Liposomal bupivacaine peripheral nerve block for the management of postoperative pain
Cochrane Systematic Reviews, 25-Aug-2016
Postoperative pain remains a significant issue with poor perioperative pain management associated with an increased risk of morbidity and mortality. Liposomal bupivacaine is an analgesic consisting of bupivacaine hydrochloride encapsulated within multiple - Lisuride for levodopa‐induced complications in Parkinson's disease
Cochrane Systematic Reviews, 25-Jan-1999
Long-term levodopa therapy in Parkinson's disease is associated with the development of motor complications including abnormal involuntary movements and a shortening response to each dose (wearing off phenomenon). It is thought that dopamine agonists can - Lisuride versus bromocriptine for levodopa‐induced complications in Parkinson's disease
Cochrane Systematic Reviews, 25-Jan-1999
Long-term levodopa therapy in Parkinson's disease is associated with the development of motor complications including abnormal involuntary movements and a shortening response to each dose (wearing off phenomenon). It is thought that dopamine agonists can - Lithium for maintenance treatment of mood disorders
Cochrane Systematic Reviews, 23-Jul-2001
Mood disorders are common, disabling and tend to be recurrent. They carry a high risk of suicide. Maintenance treatment, aimed at the prevention of relapse, is therefore of vital importance. Lithium has been used for some years as the mainstay of maintena - Lithium for schizophrenia
Cochrane Systematic Reviews, 28-Oct-2015
Many people with schizophrenia do not achieve a satisfactory treatment response with ordinary anti-psychotic drug treatment. In these cases, various add-on medications are used, among them lithium. - Lithium versus antidepressants in the long‐term treatment of unipolar affective disorder
Cochrane Systematic Reviews, 18-Oct-2006
The main rationale for the use of lithium in the long-term treatment of unipolar affective disorder is its efficacy in treating bipolar affective disorder and resistant depression. However, there is considerable uncertainty about which pharmacological int - Liver resection versus other treatments for neuroendocrine tumours in patients with resectable liver metastases
Cochrane Systematic Reviews, 15-Apr-2009
Neuroendocrine tumours are tumours of cells, which possess secretory granules and originate from the neuroectoderm. While liver resection is generally advocated in patients with resectable liver metastases, recent studies have shown good survival in patie - Lobeline for smoking cessation
Cochrane Systematic Reviews, 15-Feb-2012
Lobeline is a partial nicotine agonist, which has been used in a variety of commercially available preparations to help stop smoking. - Local anaesthetic eye drops for prevention of pain in preterm infants undergoing screening for retinopathy of prematurity
Cochrane Systematic Reviews, 7-Dec-2011
Screening examinations for retinopathy of prematurity (ROP) are performed routinely in the neonatal intensive care unit and are a recognised cause of pain in the newborn.
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