- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Diarrhoeal disease accounts for millions of child deaths every year. Although the role of flies as vectors of infectious diarrhoea has been established, fly control is not often mentioned as an approach to decrease childhood diarrhoea. Theoretically, fly - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Pancreatic and periampullary adenocarcinomas account for some of the most aggressive malignancies, and the leading causes of cancer-related mortalities. Partial pancreaticoduodenectomy (PD) with negative resection margins is the only potentially curative - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Asthma is a common respiratory condition in children that is characterised by symptoms including wheeze, shortness of breath, chest tightness, and cough. Children with asthma may be able to manage their condition more effectively by improving inhaler tech - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This is an updated version of the original Cochrane Review published in Issue 8, 2016. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Postoperative pain remains a significant issue with poor perioperative pain management associated with an increased risk of morbidity and mortality. Liposomal bupivacaine is an analgesic consisting of bupivacaine hydrochloride encapsulated within multiple - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Cervical cancer is the fourth most common cancer in women, with 528,000 estimated new cases globally in 2012. A large majority (around 85%) of the disease burden occurs in low- and middle-income countries (LMICs), where it accounts for almost 12% of all f - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Excessive alcohol use contributes significantly to physical and psychological illness, injury and death, and a wide array of social harm in all age groups. A proven strategy for reducing excessive alcohol consumption levels is to offer a brief conversatio - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Kidney transplantation is the treatment of choice for patients with end-stage kidney disease. In a previous review we concluded that the routine use of ureteric stents in kidney transplantation reduces the incidence of major urological complications (MUC) - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Using hypofractionation (fewer, larger doses of daily radiation) to treat localized prostate cancer may improve convenience and resource use. For hypofractionation to be feasible, it must be at least as effective for cancer-related outcomes and have compa - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Endoscopic assessment of mucosal disease activity is routinely used to determine eligibility and response to therapy in clinical trials of ulcerative colitis. The operating properties of the existing endoscopic scoring indices are unclear. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
The prevention of cardiovascular disease (CVD) is a key public health priority. A number of dietary factors have been associated with modifying CVD risk factors. One such factor is dietary fibre which may have a beneficial association with CVD risk factor - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Dementia is a worldwide concern. Its global prevalence is increasing. At present, there is no medication licensed to prevent or delay the onset of dementia. Inflammation has been suggested as a key factor in dementia pathogenesis. Therefore, medications w - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
A large proportion of people with advanced cancer will experience moderate to severe pain. Tapentadol is a novel, centrally acting analgesic medicine acting at the µ-opioid receptor and inhibiting noradrenaline reuptake. The efficacy of tapentadol is stat - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
The World Health Organization recommends intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine for malaria for all women who live in moderate to high malaria transmission areas in Africa. However, parasite resistance to sulf - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Central venous catheters can help with diagnosis and treatment of the critically ill. The catheter may be placed in a large vein in the neck (internal jugular vein), upper chest (subclavian vein) or groin (femoral vein). Whilst this is beneficial overall, - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Disease activity can be determined using clinical, endoscopic or histologic criteria in patients with ulcerative colitis (UC). Persistent disease activity is associated with poor outcomes. Histologic disease activity has been shown to be associated with r - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Post-traumatic stress disorder (PTSD) refers to an anxiety or trauma- and stressor-related disorder that is linked to personal or vicarious exposure to traumatic events. PTSD is associated with a range of adverse individual outcomes (e.g. poor health, sui - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Neuropathic pain is thought to arise from damage to the somatosensory nervous system. Its prevalence is increasing in line with many chronic disorders such as diabetes. All treatments have limited effectiveness. Given the evidence regarding psychological - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Poliomyelitis mainly affects unvaccinated children under five years of age, causing irreversible paralysis or even death. The oral polio vaccine (OPV) contains live attenuated virus, which can, in rare cases, cause a paralysis known as vaccine-associated - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Dentistry is a profession with a high prevalence of work-related musculoskeletal disorders (WMSD) among practitioners, with symptoms often starting as early in the career as the student phase. Ergonomic interventions in physical, cognitive, and organisati
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