- Intravenous versus inhalational techniques for rapid emergence from anaesthesia in patients undergoing brain tumour surgery
Cochrane Systematic Reviews, 4-Jan-2017
Brain tumour surgery usually is carried out with the patient under general anaesthesia. Over past years, both intravenous and inhalational anaesthetic agents have been used, but the superiority of one agent over the other is a topic of ongoing debate. Ear - Intravenous versus intramuscular prophylactic oxytocin for reducing blood loss in the third stage of labour
Cochrane Systematic Reviews,
There is general agreement that oxytocin given either through the intravenous or intramuscular route is effective in reducing postpartum blood loss. However, it is unclear whether the subtle differences between the mode of action of these routes have any - Intraventricular antibiotics for bacterial meningitis in neonates
Cochrane Systematic Reviews, 27-Jan-2020
Neonatal meningitis may be caused by bacteria, especially gram-negative bacteria, which are difficult to eradicate from the cerebrospinal fluid (CSF) using safe doses of antibiotics. In theory, intraventricular administration of antibiotics would produce - Intraventricular streptokinase after intraventricular hemorrhage in newborn infants
Cochrane Systematic Reviews, 9-Jun-2008
Hydrocephalus following intraventricular hemorrhage (IVH) is still one of the most serious complications of premature birth. Ventriculoperitoneal shunt surgery cannot be carried out early and permanent dependence on a shunt is associated with several seri - Intravesical Bacillus Calmette‐Guérin in Ta and T1 bladder cancer
Cochrane Systematic Reviews, 3-Feb-2010
Intravesical therapy with Bacillus Calmette-Guérin (BCG) aims to reduce the incidence of tumour recurrence following transurethral resection (TUR) for patients with superficial bladder cancer. - Intravesical Bacillus Calmette-Guérin versus epirubicin for Ta and T1 bladder cancer
Cochrane Systematic Reviews, 1-May-2011
Bladder cancer accounts for approximately 4.4% of adult malignancies, and approximately 80% of bladder cancer presents initially as transitional cell carcinoma that is confined to the urothelium (stage Ta) or lamina propria (stage T1). Intravesical admini - Intravesical Bacillus Calmette-Guérin versus mitomycin C for Ta and T1 bladder cancer
Cochrane Systematic Reviews, 6-Nov-2015
Tumour recurrence following transurethral resection (TUR) for Ta and T1 bladder cancer is a major clinical problem. Intravesical administration of mitomycin C (MMC) or bacillus Calmette-Guérin (BCG) has proven prophylactic activity but both are associated - Intravesical Bacillus Calmette‐Guérin versus mitomycin C for Ta and T1 bladder cancer
Cochrane Systematic Reviews, 6-Jan-2020
People with urothelial carcinoma of the bladder are at risk for recurrence and progression following transurethral resection of a bladder tumour (TURBT). Mitomycin C (MMC) and Bacillus Calmette-Guérin (BCG) are commonly used, competing forms of intravesic - Intravesical Bacillus Calmette-Guérin with interferon-alpha versus intravesical Bacillus Calmette-Guérin for treating non-muscle-invasive bladder cancer
Cochrane Systematic Reviews, 8-Mar-2017
Despite local therapies, commonly transurethral resection (TUR) followed by adjuvant treatments, non-muscle-invasive bladder cancer (NMIBC) has a high rate of recurrence and progression. Intravesical Bacillus Calmette-Guérin (BCG) has been shown to reduce - Intravesical electromotive drug administration for non‐muscle invasive bladder cancer
Cochrane Systematic Reviews, 8-Sep-2017
Electromotive drug administration (EMDA) is the use of electrical current to improve the delivery of intravesical agents to reduce the risk of recurrence in people with non-muscle invasive bladder cancer (NMIBC). It is unclear how effective this is in com - Intravesical gemcitabine for non-muscle invasive bladder cancer
Cochrane Systematic Reviews, 1-Dec-2011
Intravesical immunotherapy or chemotherapy for non-muscle invasive bladder cancer is a well established treatment for preventing or delaying tumour recurrence following tumour resection. However, up to 70% of patients may fail and new intravesical agents - Intravesical treatments for painful bladder syndrome/ interstitial cystitis
Cochrane Systematic Reviews, 5-Nov-2008
Painful Bladder Syndrome/Interstitial Cystitis (PBS/IC) occurs predominantly in women. It is a poorly-understood condition with symptoms of bladder pain, urinary frequency, urgency and nocturia. Treatments for PBS/IC include dietary/lifestyle intervention - Intravitreal low molecular weight heparin and 5‐Fluorouracil for the prevention of proliferative vitreoretinopathy following retinal reattachment surgery
Cochrane Systematic Reviews, 11-Nov-2012
Proliferative vitreoretinopathy (PVR) is a significant cause of failure in retinal reattachment surgery. Various pharmacological agents have shown potential benefit in reducing postoperative PVR risk. - Intravitreal steroids for macular edema in diabetes
Cochrane Systematic Reviews,
Diabetic macular edema (DME) is secondary to leakage from diseased retinal capillaries with thickening of central retina, and is an important cause of poor central visual acuity in people with diabetic retinopathy. Intravitreal steroids have been used to - Intravitreal steroids versus observation for macular edema secondary to central retinal vein occlusion
Cochrane Systematic Reviews, 3-Sep-2015
Central retinal vein occlusion (CRVO) is a common retinal vascular abnormality associated with conditions such as hypertension, diabetes, glaucoma, and a wide variety of hematologic disorders. Macular edema (ME) represents an important vision-threatening - Invasive urodynamic studies for the management of lower urinary tract symptoms (LUTS) in men with voiding dysfunction
Cochrane Systematic Reviews, 21-Apr-2015
Invasive urodynamic tests are used to investigate men with lower urinary tract symptoms (LUTS) and voiding dysfunction to determine a definitive objective diagnosis. The aim is to help clinicians select the treatment that is most likely to be successful. - Invasive versus non-invasive ventilation for acute respiratory failure in neuromuscular disease and chest wall disorders
Cochrane Systematic Reviews, 4-Dec-2017
Acute respiratory failure is a common life-threatening complication of acute onset neuromuscular diseases, and may exacerbate chronic hypoventilation in patients with neuromuscular disease or chest wall disorders. Standard management includes oxygen suppl - In-work tax credits for families and their impact on health status in adults
Cochrane Systematic Reviews, 1-Aug-2013
By improving two social determinants of health (poverty and unemployment) in low- and middle-income families on or at risk of welfare, in-work tax credit for families (IWTC) interventions could impact health status and outcomes in adults. - Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders
Cochrane Systematic Reviews, 11-Feb-2019
Iodine deficiency disorders (IDD) affect close to 1.9 billion people worldwide, and are a major public health concern in many countries. Among children, iodine deficiency is the main cause of potentially preventable deficits of central nervous system deve - Iodine supplementation for preventing iodine deficiency disorders in children
Cochrane Systematic Reviews, 28-Nov-2018
Iodine deficiency is the main cause of potentially preventable mental retardation in childhood, as well as causing goitre and hypothyroidism in people of all ages. It is still prevalent in large parts of the world.
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