- Intramuscular arteether for treating severe malaria
Cochrane Systematic Reviews, 13-Apr-2011
Quinine and artemisinin drugs are used in severe malaria, but quinine resistance is increasing. Arteether is a recently developed artemisinin derivative that is oil soluble, has a long elimination half life, and is more stable than other derivatives. - Intramuscular penicillin for the prevention of early onset group B streptococcal infection in newborn infants
Cochrane Systematic Reviews, 12-Mar-2012
Early-onset group B streptococcal disease (EOGBSD) is the most frequent cause of serious infection in the newborn period. Current strategies used to prevent EOGBSD are focused upon maternal antibiotic prophylaxis to reduce transmission of GBS to the infan - Intramuscular versus intravenous anti-D for preventing Rhesus alloimmunization during pregnancy
Cochrane Systematic Reviews, 5-Dec-2012
Antibodies to the red cell Rhesus D (RhD) antigen can be produced during pregnancy in a RhD-negative mother carrying a RhD-positive fetus, in particular following feto-maternal haemorrhage at birth or following any procedure that may cause feto-maternal h - Intramuscular versus intravenous prophylactic oxytocin for the third stage of labour
Cochrane Systematic Reviews, 21-Sep-2018
There is general agreement that oxytocin given either through the intramuscular or intravenous route is effective in reducing postpartum blood loss. However, it is unclear whether the subtle differences between the mode of action of these routes have any - Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for acute asthma
Cochrane Systematic Reviews, 31-May-2018
Acute asthma is a common cause of presentations to acute care centres, such as the emergency department (ED), and while the majority of patients can be discharged, relapse requiring additional medical care is common. Systemic corticosteroids are a major p - Intranasal corticosteroids for asthma control in people with coexisting asthma and rhinitis
Cochrane Systematic Reviews, 29-Mar-2009
Allergic rhinitis and asthma are mediated by similar allergic mechanisms. They may represent two manifestations of the same united airway disease and therefore intranasal corticosteroids (INCS) could improve asthma. Nevertheless none of the asthma guideli - Intranasal corticosteroids for nasal airway obstruction in children with moderate to severe adenoidal hypertrophy
Cochrane Systematic Reviews, 7-Sep-2010
This is an update of a Cochrane Review first published in The Cochrane Library in Issue 3, 2008. - Intranasal fentanyl for the management of acute pain in children
Cochrane Systematic Reviews, 13-Aug-2015
Pain is the most common symptom in the emergency setting; however, timely management of acute pain in children continues to be suboptimal. Intranasal drug delivery has emerged as an alternative method of achieving quicker drug delivery without adding to t - Intranasal ipratropium bromide for the common cold
Cochrane Systematic Reviews, 13-Jun-2013
The common cold is one of the most common illnesses in humans and constitutes an economic burden both in terms of productivity and expenditure for treatment. There is no proven cure for the common cold and symptomatic relief is the mainstay of treatment. - Intranasal or transdermal nicotine for the treatment of postoperative pain
Cochrane Systematic Reviews, 12-Jan-2016
Acute pain frequently occurs after surgical procedures. Nicotine has been explored as an adjunctive medication for management of postoperative pain. - Intranasal steroids for acute sinusitis
Cochrane Systematic Reviews, 19-Aug-2019
Acute sinusitis is a common reason for primary care visits. It causes significant symptoms and often results in time off work and school. - Intranasal steroids versus placebo or no intervention for chronic rhinosinusitis
Cochrane Systematic Reviews, 26-Apr-2016
This review is one of six looking at the primary medical management options for patients with chronic rhinosinusitis. - Intraoperative frozen section analysis for the diagnosis of early stage ovarian cancer in suspicious pelvic masses
Cochrane Systematic Reviews, 21-Sep-2016
Women with suspected early-stage ovarian cancer need surgical staging which involves taking samples from areas within the abdominal cavity and retroperitoneal lymph nodes in order to inform further treatment. One potential strategy is to surgically stage - Intraoperative imaging technology to maximise extent of resection for glioma
Cochrane Systematic Reviews, 19-Jan-2018
Extent of resection is considered to be a prognostic factor in neuro-oncology. Intraoperative imaging technologies are designed to help achieve this goal. It is not clear whether any of these sometimes very expensive tools (or their combination) should be - Intraoperative interventions for preventing surgical site infection: an overview of Cochrane Reviews
Cochrane Systematic Reviews, 31-Jan-2018
Surgical site infection (SSI) rates vary from 1% to 5% in the month following surgery. Due to the large number of surgical procedures conducted annually, the costs of these SSIs can be considerable in financial and social terms. Many interventions are use - Intraoperative mild hypothermia for postoperative neurological deficits in people with intracranial aneurysm
Cochrane Systematic Reviews, 21-Mar-2016
Rupture of an intracranial aneurysm causes aneurysmal subarachnoid haemorrhage, which is one of the most devastating clinical conditions. It can be classified into five Grades using the Hunt-Hess or World Federation of Neurological Surgeons (WFNS) scale. - Intraoperative Mitomycin C for glaucoma surgery
Cochrane Systematic Reviews, 19-Jan-2010
Trabeculectomy is performed as a treatment for glaucoma to lower the intraocular pressure (IOP). Mitomycin C (MMC) is an antimetabolite used during the initial stages of a trabeculectomy to prevent excessive postoperative scarring and thus reduce the risk - Intraoperative neuromonitoring versus visual nerve identification for prevention of recurrent laryngeal nerve injury in adults undergoing thyroid surgery
Cochrane Systematic Reviews, 17-Jan-2019
Injuries to the recurrent inferior laryngeal nerve (RILN) remain one of the major post-operative complications after thyroid and parathyroid surgery. Damage to this nerve can result in a temporary or permanent palsy, which is associated with vocal cord pa - Intraoperative use of low volume ventilation to decrease postoperative mortality, mechanical ventilation, lengths of stay and lung injury in adults without acute lung injury
Cochrane Systematic Reviews, 4-Oct-2018
Since the 2000s, there has been a trend towards decreasing tidal volumes for positive pressure ventilation during surgery. This an update of a review first published in 2015, trying to determine if lower tidal volumes are beneficial or harmful for patient - Intrapartum antibiotics for known maternal Group B streptococcal colonization
Cochrane Systematic Reviews, 8-Aug-2016
Maternal colonization with group B streptococcus (GBS) during pregnancy increases the risk of neonatal infection by vertical transmission. Administration of intrapartum antibiotic prophylaxis (IAP) during labor has been associated with a reduction in earl
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