- Antibiotic regimens for secondary peritonitis of gastrointestinal origin in adults
Cochrane Systematic Reviews, 26-Mar-2012
Secondary peritonitis is associated with a high mortality rate and if not treated successfully leads to development of abscesses, severe sepsis and multi-organ failure. Source control and adjunctive antibiotics are the mainstay of treatment. However, no c - Antibiotic regimens for suspected early neonatal sepsis
Cochrane Systematic Reviews, 29-Oct-2008
Early acquired infection may cause severe illness or death in the neonatal period. Prompt treatment with antibiotics has shown to reduce mortality. It is not clear which antibiotic regimen is suitable for treatment of presumed early neonatal sepsis. - Antibiotic regimens for suspected late onset sepsis in newborn infants
Cochrane Systematic Reviews, 17-Apr-2012
Late onset neonatal sepsis (systemic infection after 48 hours of age) continues to be a significant cause of morbidity and mortality. Early treatment with antibiotics is essential as infants can deteriorate rapidly. It is not clear which antibiotic regime - Antibiotic regimens for the empirical treatment of newborn infants with necrotising enterocolitis
Cochrane Systematic Reviews, 9-Jul-2012
Although the exact aetiology of necrotising enterocolitis (NEC) remains unknown, research suggests that it is multifactorial; suspected pathophysiological mechanisms include immaturity, intestinal ischaemia, disruption of intestinal mucosal integrity, for - Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis
Cochrane Systematic Reviews, 25-Apr-2017
Respiratory tract infection with Pseudomonas aeruginosa occurs in most people with cystic fibrosis. Once chronic infection is established, Pseudomonas aeruginosa is virtually impossible to eradicate and is associated with increased mortality and morbidity - Antibiotic therapy for adults with neurosyphilis
Cochrane Systematic Reviews, 23-May-2019
Neurosyphilis is an infection of the central nervous system, caused by Treponema pallidum, a spirochete capable of infecting almost any organ or tissue in the body causing neurological complications due to the infection. This disease is a tertiary manifes - Antibiotic therapy for pelvic inflammatory disease
Cochrane Systematic Reviews, 24-Apr-2017
Pelvic inflammatory disease (PID) is an infection that affects 4% to 12% of young women, and is one of the most common causes of morbidity in this age group. The main intervention for acute PID is the use of broad-spectrum antibiotics which cover Chlamydi - Antibiotic therapy for preventing infections in people with acute stroke
Cochrane Systematic Reviews, 9-Jan-2018
Stroke is the main cause of disability in high-income countries and ranks second as a cause of death worldwide. Infections occur frequently after stroke and may adversely affect outcome. Preventive antibiotic therapy in the acute phase of stroke may reduc - Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis
Cochrane Systematic Reviews, 23-Mar-2010
Pancreatic necrosis may complicate severe acute pancreatitis, and is detectable by computed tomography (CT). If it becomes infected mortality increases, but the use of prophylactic antibiotics raises concerns about antibiotic resistance and fungal infecti - Antibiotic therapy for Shigella dysentery
Cochrane Systematic Reviews, 7-Jul-2010
Shigella dysentery is a relatively common illness and occasionally causes death, worldwide. Mild symptoms are self-limiting but in more severe cases, antibiotics are recommended for cure and preventing relapse. The antibiotics recommended are diverse, hav - Antibiotic therapy for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) in non surgical wounds
Cochrane Systematic Reviews, 15-Nov-2013
Non surgical wounds include chronic ulcers (pressure or decubitus ulcers, venous ulcers, diabetic ulcers, ischaemic ulcers), burns and traumatic wounds. The prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonisation (i.e. presence of MR - Antibiotic therapy for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in surgical wounds
Cochrane Systematic Reviews, 6-Aug-2013
Methicillin-resistant Staphylococcus aureus (MRSA) infection after surgery is usually rare, but incidence can be up to 33% in certain types of surgery. Postoperative MRSA infection can occur as surgical site infections (SSI), chest infections, or bloodstr - Antibiotic therapy versus no antibiotic therapy for children aged two to 59 months with WHO-defined non-severe pneumonia and wheeze
Cochrane Systematic Reviews, 20-May-2014
Worldwide, pneumonia is the leading cause of death among children under five years of age and accounts for approximately two million deaths annually. The World Health Organization (WHO) has developed case management guidelines based on simple clinical sig - Antibiotic treatment for Burkholderia cepacia complex in people with cystic fibrosis experiencing a pulmonary exacerbation
Cochrane Systematic Reviews, 14-Jan-2016
Chronic pulmonary infection is a hallmark of lung disease in cystic fibrosis. Infections dominated by organisms of the Burkholderia cepacia complex, a group of at least 18 closely-related species of gram-negative bacteria, are particularly difficult to tr - Antibiotic treatment for Clostridium difficile-associated diarrhoea in adults
Cochrane Systematic Reviews, 3-Mar-2017
Clostridium difficile (C. difficile) is recognized as a frequent cause of antibiotic-associated diarrhoea and colitis. This review is an update of a previously published Cochrane review. - Antibiotic treatment for newborns with congenital syphilis
Cochrane Systematic Reviews, 12-Feb-2019
Congenital syphilis continues to be a substantial public health problem in many parts of the world. Since the first use of penicillin for the treatment of syphilis in 1943, which was a notable early success, it has remained the preferred and standard trea - Antibiotic treatment for nontuberculous mycobacteria lung infection in people with cystic fibrosis
Cochrane Systematic Reviews, 19-Dec-2016
Nontuberculous mycobacteria are mycobacteria, other than those in the Mycobacterium tuberculosis complex, and are commonly found in the environment. Nontuberculous mycobacteria species (most commonly Mycobacterium avium complex and Mycobacterium abscessus - Antibiotic treatment for spontaneous bacterial peritonitis in people with decompensated liver cirrhosis: a network meta-analysis
Cochrane Systematic Reviews, 10-Sep-2019
Approximately 2.5% of all hospitalisations in people with cirrhosis are for spontaneous bacterial peritonitis (SBP). Antibiotics, in addition to supportive treatment (fluid and electrolyte balance, treatment of shock), form the mainstay treatments of SBP. - Antibiotic treatment for Stenotrophomonas maltophilia in people with cystic fibrosis
Cochrane Systematic Reviews, 26-Mar-2019
Stenotrophomonas maltophilia is one of the most common emerging multi-drug resistant organisms found in the lungs of people with cystic fibrosis and its prevalence is increasing. Chronic infection with Stenotrophomonas maltophilia has recently been shown - Antibiotic treatment for the sexual partners of women with bacterial vaginosis
Cochrane Systematic Reviews, 27-Sep-2016
Bacterial vaginosis (BV) is an infection that has a prevalence between 10% to 50% worlwide. BV results in an imbalance of the normal vaginal flora. Microorganisms associated with BV have been isolated from the normal flora of the male genital tract, and t
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