- Interventions for treating intrahepatic cholestasis in people with sickle cell disease
Cochrane Systematic Reviews, 22-Jun-2020
Sickle cell disease is the most common hemoglobinopathy occurring worldwide and sickle cell intrahepatic cholestasis is a complication long recognized in this population. Cholestatic liver diseases are characterized by impaired formation or excretion (or - Interventions for treating iron deficiency anaemia in inflammatory bowel disease
Cochrane Systematic Reviews, 20-Jan-2021
Inflammatory bowel disease affects approximately seven million people globally. Iron deficiency anaemia can occur as a common systemic manifestation, with a prevalence of up to 90%, which can significantly affect quality of life, both during periods of ac - Interventions for treating isolated diaphyseal fractures of the ulna in adults
Cochrane Systematic Reviews, 13-Jun-2012
Isolated fractures of the shaft of the ulna, which are often sustained when the forearm is raised to shield against a blow, are generally treated on an outpatient basis. This is an update of a Cochrane review first published in 1998 and last updated in 20 - Interventions for treating leg ulcers in people with sickle cell disease
Cochrane Systematic Reviews, 9-Jan-2021
The frequency of skin ulceration makes an important contributor to the morbidity burden in people with sickle cell disease. Many treatment options are available to the healthcare professional, although it is uncertain which treatments have been assessed f - Interventions for treating lymphocytic colitis
Cochrane Systematic Reviews, 13-Jul-2017
Lymphocytic colitis is a cause of chronic diarrhea. It is a subtype of microscopic colitis characterized by chronic, watery, non-bloody diarrhea and normal endoscopic and radiologic findings. The etiology of this disorder is unknown.Therapy is based mainl - Interventions for treating mallet finger injuries
Cochrane Systematic Reviews, 12-May-2008
Mallet finger, also called drop or baseball finger, is where the end of a finger cannot be actively straightened out due to injury of the extensor tendon mechanism. Treatment commonly involves splintage of the finger for six or more weeks. Less frequently - Interventions for treating melioidosis
Cochrane Systematic Reviews, 21-Oct-2002
Melioidosis is an infectious disease that occurs in tropical regions, particularly in Thailand. It is caused by the bacterium Burkholderia pseudomallei and is a serious condition which can be fatal. Beta-lactam antibiotics have dramatically reduced the ri - Interventions for treating neuropathic pain in people with sickle cell disease
Cochrane Systematic Reviews, 5-Jul-2019
Pain is the hallmark of sickle cell disease (SCD) and it can be severe, frequent and unpredictable. Although nociceptive pain is more common, at times, people with SCD may have neuropathic pain. The latter can occur due to peripheral or central nerve inju - Interventions for treating obesity in children
Cochrane Systematic Reviews, 7-Mar-2019
Child and adolescent obesity is increasingly prevalent, and can be associated with significant short- and long-term health consequences. - Interventions for treating oral candidiasis for patients with cancer receiving treatment
Cochrane Systematic Reviews, 7-Jul-2010
Treatment of cancer is increasingly effective but is associated with short and long term side effects. Oral and gastrointestinal side effects, including oral candidiasis, remain a major source of illness despite the use of a variety of agents to treat the - Interventions for treating oral leukoplakia to prevent oral cancer
Cochrane Systematic Reviews, 29-Jul-2016
Oral leukoplakia is a relatively common oral lesion that, in a small proportion of people, precedes the development of oral cancer. Most leukoplakias are asymptomatic; therefore, the primary objective of treatment should be to prevent onset of cancer. Thi - Interventions for treating oral lichen planus: corticosteroid therapies
Cochrane Systematic Reviews, 28-Feb-2020
Oral lichen planus (OLP) is a relatively common chronic T cell-mediated disease, which can cause significant pain, particularly in its erosive or ulcerative forms. As pain is the indication for treatment of OLP, pain resolution is the primary outcome for - Interventions for treating oral mucositis for patients with cancer receiving treatment
Cochrane Systematic Reviews, 6-Sep-2010
Treatment of cancer is increasingly effective but associated with short and long term side effects. Oral side effects, including oral mucositis (mouth ulceration), remain a major source of illness despite the use of a variety of agents to treat them. - Interventions for treating oro‐antral communications and fistulae due to dental procedures
Cochrane Systematic Reviews, 16-Aug-2018
An oro-antral communication is an unnatural opening between the oral cavity and maxillary sinus. When it fails to close spontaneously, it remains patent and is epithelialized to develop into an oro-antral fistula. Various surgical and non-surgical techniq - Interventions for treating osteoarthritis of the big toe joint
Cochrane Systematic Reviews, 3-Aug-2010
Osteoarthritis affecting of the big toe joint of the foot (hallux limitus or rigidus) is a common and painful condition. Although several treatments have been proposed, few have been adequately evaluated. - Interventions for treating osteochondral defects of the talus in adults
Cochrane Systematic Reviews, 23-Jun-2010
Osteochondral defects of the talus are usually a consequence of trauma. They can cause chronic pain and serious disability. Various interventions, non-surgical and surgical, have been used for treating these defects. - Interventions for treating pain and disability in adults with complex regional pain syndrome‐ an overview of systematic reviews
Cochrane Systematic Reviews, 30-Apr-2013
There is currently no strong consensus regarding the optimal management of complex regional pain syndrome although a multitude of interventions have been described and are commonly used. - Interventions for treating painful nipples among breastfeeding women
Cochrane Systematic Reviews, 12-Dec-2014
Leading health authorities all recommend exclusive breastfeeding to six months' postpartum. While most women initiate breastfeeding, many discontinue due to difficulties encountered rather than maternal choice. One common breastfeeding difficulty is painf - Interventions for treating painful sickle cell crisis during pregnancy
Cochrane Systematic Reviews, 21-Jan-2009
Sickle cell disease is a group of genetic haemoglobin disorders. All over the world, about 300,000 children with these disorders are born each year. Acute sickle cell pain episodes are the most common cause of hospitalisation. Pregnancy in women with sick - Interventions for treating people with symptoms of bladder pain syndrome: a network meta‐analysis
Cochrane Systematic Reviews, 30-Jul-2020
Bladder pain syndrome (BPS), which includes the condition of interstitial cystitis, is a poorly understood clinical condition for which patients present with varying symptoms. Management of BPS is challenging for both patients and practitioners. At presen
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