- Interventions for the management of malignant pleural effusions: a network meta‐analysis
Cochrane Systematic Reviews, 21-Apr-2020
Malignant pleural effusion (MPE) is a common problem for people with cancer and usually associated with considerable breathlessness. A number of treatment options are available to manage the uncontrolled accumulation of pleural fluid, including administra - Interventions for the management of mandibular fractures
Cochrane Systematic Reviews, 4-Jul-2013
Fractures of the mandible (lower jaw) are a common occurrence and usually related to interpersonal violence or road traffic accidents. Mandibular fractures may be treated using open (surgical) and closed (non-surgical) techniques. Fracture sites are immob - Interventions for the management of obesity in people with bipolar disorder
Cochrane Systematic Reviews,
Bipolar disorder is one of the most common serious mental illnesses, affecting approximately 60 million people worldwide. Characterised by extreme alterations in mood, cognition, and behaviour, bipolar disorder can have a significant negative impact on th - Interventions for the management of oral submucous fibrosis
Cochrane Systematic Reviews, 29-Jul-2008
Oral submucous fibrosis (OSF) is a chronic disease of the oral cavity which is more commonly found in patients in the Asian subcontinent and the Far East. It is characterised by the progressive build up of constricting bands of collagen in the cheeks and - Interventions for the management of submucous cleft palate
Cochrane Systematic Reviews, 19-Jan-2016
Submucous cleft palate (SMCP) is a common congenital malformation of the soft palate which may present as velopharyngeal insufficiency (VPI), which can affect the quality and intelligibility of speech. Surgical techniques, which can be used to reconstruct - Interventions for the physical aspects of sexual dysfunction in women following pelvic radiotherapy
Cochrane Systematic Reviews, 11-Feb-2015
Following pelvic radiotherapy (RT), a proportion of women experience problems related to sexual function, which are multifactorial in origin. The physical components relate to distortion of the perineum and vagina, which may occur as a result of surgery a - Interventions for the prevention and management of oropharyngeal candidiasis associated with HIV infection in adults and children
Cochrane Systematic Reviews, 6-Oct-2010
Oral candidiasis (OC) associated with human immunodeficiency virus (HIV) infection occurs commonly and recurs frequently, often presenting as an initial manifestation of the disease. Left untreated, these lesions contribute considerably to the morbidity a - Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer
Cochrane Systematic Reviews, 9-Nov-2008
Treatment of cancer is increasingly effective, but associated with oral complications such as mucositis, fungal infections, bacterial infections and viral infections such as the herpes simplex virus (HSV). - Interventions for the prevention and treatment of pes cavus
Cochrane Systematic Reviews, 9-Nov-2010
People with pes cavus frequently suffer foot pain, which can lead to significant disability. Despite anecdotal reports, rigorous scientific investigation of this condition and how best to manage it is lacking. - Interventions for the prevention of mycobacterium avium complex in adults and children with HIV
Cochrane Systematic Reviews, 30-Apr-2013
Mycobacterium avium complex (MAC) infection is a common complication of advanced acquired immunodeficiency syndrome (AIDS) disease and is an independent predictor of mortality and shortened survival. - Interventions for the prevention of nutritional rickets in term born children
Cochrane Systematic Reviews, 3-Nov-2008
Nutritional rickets is a disease of growing children leading to bone deformities, bone pain, convulsions or delayed motor development. Today, high-incidence of nutritional rickets is mainly found in low-income countries. - Interventions for the prevention of OHSS in ART cycles: an overview of Cochrane reviews
Cochrane Systematic Reviews, 23-Jan-2017
Ovarian hyperstimulation syndrome (OHSS) in assisted reproductive technology (ART) cycles is a treatment-induced disease that has an estimated prevalence of 20% to 33% in its mild form and 3% to 8% in its moderate or severe form. These numbers might even - Interventions for the prevention of postoperative ear discharge after insertion of ventilation tubes (grommets) in children
Cochrane Systematic Reviews, 29-Mar-2013
Grommets are frequently inserted in children's ears for acute otitis media and otitis media with effusion. A common complication is postoperative ear discharge (otorrhoea). A wide range of treatments are used to prevent the discharge, but there is no cons - Interventions for the prevention of recurrent erysipelas and cellulitis
Cochrane Systematic Reviews, 19-Jun-2017
Erysipelas and cellulitis (hereafter referred to as 'cellulitis') are common bacterial skin infections usually affecting the lower extremities. Despite their burden of morbidity, the evidence for different prevention strategies is unclear. - Interventions for the reduction of prescribed opioid use in chronic non‐cancer pain
Cochrane Systematic Reviews,
This is the first update of the original Cochrane Review published in 2013. The conclusions of this review have not changed from the 2013 publication. People with chronic non-cancer pain who are prescribed and are taking opioids can have a history of long - Interventions for the restorative care of amelogenesis imperfecta in children and adolescents
Cochrane Systematic Reviews, 11-Mar-2014
Amelogenesis imperfecta (AI) is a tooth development disorder in which the teeth are covered with thin, abnormally formed enamel. This enamel is easily fractured and damaged, which affects the appearance of the teeth, especially if left untreated. Negative - Interventions for the symptoms and signs resulting from jellyfish stings
Cochrane Systematic Reviews, 27-Oct-2015
Jellyfish envenomations are common amongst temperate coastal regions and vary in severity depending on the species. Stings result in a variety of symptoms and signs, including pain, dermatological reactions and, in some species, Irukandji syndrome (includ - Interventions for the treatment of borderline ovarian tumours
Cochrane Systematic Reviews, 26-Feb-2014
The safety of conservative surgery and the benefit of additional interventions after surgery for borderline ovarian tumours are unknown. - Interventions for the treatment of brain radionecrosis after radiotherapy or radiosurgery
Cochrane Systematic Reviews, 9-Jul-2018
Brain radionecrosis (tissue death caused by radiation) can occur following high-dose radiotherapy to brain tissue and can have a significant impact on a person's quality of life (QoL) and function. The underlying pathophysiological mechanism remains uncle - Interventions for the treatment of decreased bone mineral density associated with HIV infection
Cochrane Systematic Reviews, 10-Nov-2008
Decreased bone mineral density (BMD) occurs more commonly in patients with HIV than in the general population, making this group more susceptible to fragility fractures. However, bone loss is under-treated in patients with HIV.
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