- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
People with thrombocytopenia often require a surgical procedure. A low platelet count is a relative contraindication to surgery due to the risk of bleeding. Platelet transfusions are used in clinical practice to prevent and treat bleeding in people with t - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Serious illness is often characterised by physical/psychological problems, family support needs, and high healthcare resource use. Hospital-based specialist palliative care (HSPC) has developed to assist in better meeting the needs of patients and their f - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
A previous Cochrane review has shown that exercise-based cardiac rehabilitation (CR) can benefit myocardial infarction and post-revascularisation patients. However, the impact on stable angina remains unclear and guidance is inconsistent. Whilst recommend - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Alcohol is consumed by over 2 billion people worldwide. It is a common substance of abuse and its use can lead to more than 200 disorders including hypertension. Alcohol has both acute and chronic effects on blood pressure. This review aimed to quantify t - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Extent of resection is considered to be a prognostic factor in neuro-oncology. Intraoperative imaging technologies are designed to help achieve this goal. It is not clear whether any of these sometimes very expensive tools (or their combination) should be - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
In the absence of bleeding, plasma is commonly transfused to people prophylactically to prevent bleeding. In this context, it is transfused before operative or invasive procedures (such as liver biopsy or chest drainage tube insertion) in those considered - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Thromboangiitis obliterans, also known as Buerger's disease, is a non-atherosclerotic, segmental inflammatory pathology that most commonly affects the small- and medium-sized arteries, veins, and nerves in the upper and lower extremities. The etiology is - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Several comparative randomised controlled trials (RCTs) have been performed including combinations of tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors since the publication of a Cochrane Review on targeted therapy for metastatic renal ce - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Bipolar disorder is one of the most common serious mental illnesses, affecting approximately 60 million people worldwide. Characterised by extreme alterations in mood, cognition, and behaviour, bipolar disorder can have a significant negative impact on th - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Biologic disease-modifying anti-rheumatic drugs (DMARDs: referred to as biologics) are effective in treating rheumatoid arthritis (RA), however there are few head-to-head comparison studies. Our systematic review, standard meta-analysis and network meta-a - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Pain is a common symptom with cancer, and 30% to 50% of all people with cancer will experience moderate to severe pain that can have a major negative impact on their quality of life. Opioid (morphine-like) drugs are commonly used to treat moderate or seve - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
School dental screening refers to visual inspection of children’s oral cavity in a school setting followed by making parents aware of their child’s current oral health status and treatment needs. Screening at school intends to identify children at an earl - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Pitavastatin is the newest statin on the market, and the dose-related magnitude of effect of pitavastatin on blood lipids is not known. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Larviciding refers to the regular application of chemical or microbial insecticides to water bodies or water containers to kill the aquatic immature forms of the mosquito (the larvae and pupae). - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
There is evidence that implantable cardioverter-defibrillator (ICD) for primary prevention in people with an ischaemic cardiomyopathy improves survival rate. The evidence supporting this intervention in people with non-ischaemic cardiomyopathy is not as d - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Regular blood pressure (BP) measurement is crucial for the diagnosis and management of hypertensive disorders in pregnancy, such as pre-eclampsia. BP can be measured in various settings, such as conventional clinics or self-measurement at home, and with d - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Glaucoma is a leading cause of irreversible blindness. A number of minimally-invasive surgical techniques have been introduced as a treatment to prevent glaucoma from progressing; ab interno trabecular bypass surgery with the Schlemm's canal Hydrus micros - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Postpartum haemorrhage (PPH), defined as a blood loss of 500 mL or more after birth, is the leading cause of maternal death worldwide. The World Health Organization (WHO) recommends that all women giving birth should receive a prophylactic uterotonic agen - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Parents and carers have a major influence on children's learning and development from birth, through the school years, and into adulthood. Parental contributions to education include providing a secure environment in which to learn, providing intellectual - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Sickle cell disease (SCD), one of the most common inherited disorders, is associated with vaso-occlusive pain episodes and haemolysis leading to recurrent morbidity, hospital admissions and work or school absenteeism. The crises are conventionally treated
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