- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Human immunodeficiency virus (HIV) continues to be a leading cause of morbidity and mortality, particularly in sub-Saharan Africa. Although antiretroviral drugs have helped to improve the quality of life and life expectancy of HIV-positive individuals, th - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Excision of the transformation zone of the cervix is the most commonly used approach to treat cervical precancerous lesions (cervical intraepithelial neoplasia (CIN)) to reduce the risk of developing cervical cancer. As the excision of the transformation - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
A pressure injury (PI), also referred to as a 'pressure ulcer', or 'bedsore', is an area of localised tissue damage caused by unrelieved pressure, friction, or shearing on any part of the body. Immobility is a major risk factor and manual repositioning a - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Delirium is defined as a disturbance in attention, awareness and cognition with reduced ability to direct, focus, sustain and shift attention, and reduced orientation to the environment. Critically ill patients in the intensive care unit (ICU) frequently - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Delusional disorder is commonly considered to be difficult to treat. Antipsychotic medications are frequently used and there is growing interest in a potential role for psychological therapies such as cognitive behavioural therapy (CBT) in the treatment o - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This is an update of a Cochrane Review that was originally published in 2014, Issue 2.? ? The presence of residual disease after primary debulking surgery is a highly significant prognostic factor in women with advanced ovarian cancer. In up to 60% of wom - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Muscle soreness typically occurs after intense exercise, unaccustomed exercise or actions that involve eccentric contractions where the muscle lengthens while under tension. It peaks between 24 and 72 hours after the initial bout of exercise. Many people - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Women with a prior caesarean delivery have an increased risk of uterine rupture and for women subsequently requiring induction of labour it is unclear which method is preferable to avoid adverse outcomes. This is an update of a review that was published i - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Awake fibreoptic intubation (AFOI) frequently requires sedation, anxiolysis and relief of discomfort without impairing ventilation and depressing cardiovascular function. The goal is to allow the patient to be responsive and co-operative. Medications such - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Supportive, positive family environments have been shown to improve outcomes for patients with schizophrenia in contrast with family environments that express high levels of criticism, hostility, or over-involvement, which have poorer outcomes and have mo - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Sudden cardiac arrest (SCA) is a common health problem associated with high levels of mortality. Cardiac arrest is caused by three groups of dysrhythmias: ventricular fibrillation (VF) or pulseless ventricular tachycardia (VT), pulseless electric activity - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Psoriasis is a chronic inflammatory skin condition that can markedly reduce life quality. Several systemic therapies exist for moderate to severe psoriasis, including oral fumaric acid esters (FAE). These contain dimethyl fumarate (DMF), the main active i - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Group A streptococcus (GAS) accounts for 20% to 40% of cases of pharyngitis in children; the remaining cases are caused by viruses. Compared with throat culture, rapid antigen detection tests (RADTs) offer diagnosis at the point of care (within five to 10 - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Please see Appendix 4 for a glossary of terms. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Periodontal disease and dental caries are highly prevalent oral diseases that can lead to pain and discomfort, oral hygiene and aesthetic problems, and eventually tooth loss, all of which can be costly to treat and are a burden to healthcare systems. Tric - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
People with dementia living in the community, that is in their own homes, are often not engaged in meaningful activities. Activities tailored to their individual interests and preferences might be one approach to improve quality of life and reduce challen - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Cataract is a leading cause of blindness worldwide. Cataract surgery is commonly performed but can result in postoperative inflammation of the eye. Inadequately controlled inflammation increases the risk of complications. Non-steroidal anti-inflammatory d - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Thalassaemia is a genetic disorder of the haemoglobin protein in red blood cells. It has been historically classified into thalassaemia minor, intermedia and major, depending on the genetic defect and severity of the disease. The clinical presentation of - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Epithelial ovarian cancer (EOC) is often diagnosed at an advanced stage, requiring primary cytoreductive surgery and combination chemotherapy for its first-line management. Currently, the recommended standard first-line chemotherapy is platinum-based, usu - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This is an updated version of the original Cochrane review published in 2015, Issue 10.
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