- Interventions for leg cramps in pregnancy
Cochrane Systematic Reviews, 21-Jan-2002
Many women experience leg cramps in pregnancy. They become more common as pregnancy progresses and are especially troublesome at night. - Interventions for leg cramps in pregnancy
Cochrane Systematic Reviews, 4-Dec-2020
Leg cramps are a common problem in pregnancy. Various interventions have been used to treat them, including drug, electrolyte and vitamin therapies, and non-drug therapies. This Cochrane Review is an update of a review first published in 2015. - Interventions for lowering plasma homocysteine levels in dialysis patients
Cochrane Systematic Reviews, 31-May-2016
People with end-stage kidney disease (ESKD) have high rates of cardiovascular events. Randomised controlled trials (RCTs) of homocysteine-lowering therapies have not shown reductions in cardiovascular event rates in the general population. However, people - Interventions for lowering plasma homocysteine levels in kidney transplant recipients
Cochrane Systematic Reviews, 24-Apr-2015
Elevated homocysteine levels have been shown to be an independent risk factor for cardiovascular disease. However studies of homocysteine lowering in general and end-stage kidney disease (ESKD) populations have not demonstrated a reduction in cardiovascul - Interventions for maintenance of surgically induced remission in Crohn’s disease: a network meta‐analysis
Cochrane Systematic Reviews, 12-Sep-2019
Crohn's disease (CD) is a chronic disease of the gut. About 75% of people with CD undergo surgery at least once in their lifetime to induce remission. However, as there is no known cure for the disease, patients usually experience a recurrence even after - Interventions for managing asthma in pregnancy
Cochrane Systematic Reviews, 21-Oct-2014
Asthma is the most common respiratory disorder complicating pregnancy, and is associated with a range of adverse maternal and perinatal outcomes. There is strong evidence however, that the adequate control of asthma can improve health outcomes for mothers - Interventions for managing halitosis
Cochrane Systematic Reviews, 11-Dec-2019
Halitosis or bad breath is a symptom in which a noticeably unpleasant breath odour is present due to an underlying oral or systemic disease. 50% to 60% of the world population has experienced this problem which can lead to social stigma and loss of self-c - Interventions for managing medication‐related osteonecrosis of the jaw
Cochrane Systematic Reviews, 6-Oct-2017
Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse reaction experienced by some individuals to certain medicines commonly used in the treatment of cancer and osteoporosis (e.g. bisphosphonates, denosumab and antiangiogenic agents) and - Interventions for managing oral ulcers in Behçet's disease
Cochrane Systematic Reviews, 25-Sep-2014
Behçet's disease is a chronic inflammatory vasculitis that can affect multiple systems. Mucocutaneous involvement is common, as is the involvement of many other systems such as the central nervous system and skin. Behç¸et's disease can cause significant m - Interventions for managing relapse of the lower front teeth after orthodontic treatment
Cochrane Systematic Reviews, 11-Mar-2014
Orthodontic relapse can be defined as the tendency for teeth to return to their pre-treatment position, and this occurs especially in lower front teeth (lower canines and lower incisors). Retention, to maintain the position of corrected teeth, has become - Interventions for managing skeletal muscle spasticity following traumatic brain injury
Cochrane Systematic Reviews, 22-Nov-2017
Skeletal muscle spasticity is a major physical complication resulting from traumatic brain injury (TBI), which can lead to muscle contracture, joint stiffness, reduced range of movement, broken skin and pain. Treatments for spasticity include a range of p - Interventions for managing taste disturbances
Cochrane Systematic Reviews, 18-Dec-2017
The sense of taste is very much essential to the overall health of an individual. It is a necessary component to enjoy one's food, which in turn provides nutrition to an individual. Any disturbance in taste perception can hamper quality of life in such pa - Interventions for managing temporomandibular joint osteoarthritis
Cochrane Systematic Reviews, 18-Apr-2012
Osteoarthritis (OA) is the most common form of arthritis of the temporomandibular joint (TMJ), and can often lead to severe pain in the orofacial region. Management options for TMJ OA include reassurance, occlusal appliances, physical therapy, medication - Interventions for melanoma in situ, including lentigo maligna
Cochrane Systematic Reviews, 19-Dec-2014
Malignant melanoma is a form of skin cancer associated with significant mortality once it has spread beyond the skin. Melanoma in situ (MIS) is the earliest histologically recognisable stage of malignant melanoma and represents a precursor of invasive mel - Interventions for melasma
Cochrane Systematic Reviews, 14-Jun-2010
Melasma is an acquired symmetrical pigmentary disorder where confluent grey-brown patches typically appear on the face. Available treatments for melasma are unsatisfactory. - Interventions for men and women with their first episode of genital herpes
Cochrane Systematic Reviews, 30-Aug-2016
Genital herpes is incurable, and is caused by the herpes simplex virus (HSV). First-episode genital herpes is the first clinical presentation of herpes that a person experiences. Current treatment is based around viral suppression in order to decrease the - Interventions for metabolic bone disease in children with chronic kidney disease
Cochrane Systematic Reviews, 12-Nov-2015
Bone disease is common in children with chronic kidney disease (CKD) and when untreated may result in bone deformities, bone pain, fractures and reduced growth rates. This is an update of a review first published in 2010. - Interventions for minimal change disease in adults with nephrotic syndrome
Cochrane Systematic Reviews, 1-Mar-2022
Steroids have been used widely since the early 1970s for the treatment of adult-onset minimal change disease (MCD). Recently, newer agents have been used in adult MCD aiming to reduce the risk of adverse effects. The response rates to immunosuppressive ag - Interventions for Mooren's ulcer
Cochrane Systematic Reviews, 9-Jan-2014
Mooren's ulcer is a chronic, painful peripheral ulcer of the cornea. Its cause is unknown but it can or will lead to loss of vision if untreated. Severe pain is common in patients with Mooren's ulcer and the eye(s) may be intensely reddened, inflamed and - Interventions for morphea
Cochrane Systematic Reviews, 16-Jul-2019
Morphea (morphoea) is an immune-mediated disease in which excess synthesis and deposition of collagen in the skin and underlying connective tissues results in hardened cutaneous areas. Morphea has different clinical features according to the subtype and s
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