- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Chemotherapeutic agents such as topotecan can be used as salvage treatment in epithelial ovarian carcinoma (EOC). The effects of using topotecan as a therapeutic agent have not been previously been systematically reviewed. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Pneumocystis pneumonia (PCP) is a disease affecting immunocompromised patients. PCP among these patients is associated with significant morbidity and mortality. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Alzheimer's disease (AD) has become a major public health problem around the world due to its increasing prevalence, long duration, caregiver burden, and high financial cost of care. The degeneration of acetylcholine-containing neurons in the basal forebr - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Pseudomonas aeruginosa is the most common bacterial pathogen causing lung infections in people with cystic fibrosis and appropriate antibiotic therapy is vital. Antibiotics for pulmonary exacerbations are usually given intravenously, and for long-term tr - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Treating vaso-occlusive painful crises in people with sickle cell disease is complex and requires multiple interventions. Extra fluids are routinely given as adjunct treatment, regardless of the individual's state of hydration with the aim of slowing or s - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
The prevalence of epilepsy among people with intellectual disabilities is much higher than in the general population. Seizures in this population are often complex and refractory to treatment and antiepileptic medication may have a profound effect upon be - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Acute traumatic brain injury is a leading cause of death and disability in young adults. Numerous pharmacological and non-pharmacological tools have been investigated and considered as potential mechanisms for improving neurological outcome. Magnesium has - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This is an update of a Cochrane review first published in The Cochrane Library in Issue 1, 2010. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This is an update of a Cochrane review first published in The Cochrane Library in Issue 4, 2007 and previously updated in 2011. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Angiogenesis inhibitors have been developed to block tumour angiogenesis and target vascular endothelial cells. While some of them have already been approved by the health authorities and are successfully integrated into patient care, many others are stil - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
There is increasing evidence that physical activity supports healthy ageing. Exercise is helpful for cardiovascular, respiratory and musculoskeletal systems, among others. Aerobic activity, in particular, improves cardiovascular fitness and, based on rece - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Vascular dementia (VD) is a syndrome or diagnosis that has different causes and clinical manifestations relating to several different vascular mechanisms and changes in the brain. Some traditional Chinese herbal medicines were developed for treating VD. Y - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Lack of physical stimulation may contribute to metabolic bone disease of preterm infants, resulting in poor bone mineralization and growth. Physical activity programs combined with adequate nutrition might help to promote bone mineralization and growth. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Fluid restriction is often recommended as part of the management of infants with early or established bronchopulmonary dysplasia (BPD). - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Nasal continuous positive airway pressure (NCPAP) is a strategy for maintaining positive airway pressure throughout the respiratory cycle through the application of bias flow of respiratory gas to an apparatus attached to the nose. Treatment with NCPAP is - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Sepsis is a common problem in preterm and term infants. The incidence of neonatal sepsis has declined, but mortality remains high. Recombinant human activated protein C (rhAPC) possess a broad spectrum of activity modulating coagulation and inflammation. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is the most common neurodegenerative disorder of the motor system in adults. Pain in ALS is a frequent symptom especially in the later stages of disease and can have a pronounc - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Scoliosis in patients with Duchenne muscular dystrophy (DMD) is usually progressive and is treated with surgery. However, it is unclear whether the existing evidence is sufficiently scientifically rigorous to support a recommendation for spinal surgery fo - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Paraproteinaemic neuropathy refers to those neuropathies associated with a monoclonal gammopathy or paraprotein. The most common of these present with a chronic, predominantly sensory, symmetrical neuropathy, similar to chronic inflammatory demyelinating - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Unintended pregnancy among adolescents represents an important public health challenge in high-income countries, as well as middle- and low-income countries. Numerous prevention strategies such as health education, skills-building and improving accessibil
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