- Angiogenesis‐inhibitors for metastatic thyroid cancer
Cochrane Systematic Reviews, 17-Mar-2010
Systemic cytostatic therapies for advanced, metastatic thyroid carcinomas have been poorly effective. Tumor growth and metastasis depend on blood supply and blood vessel formation (angiogenesis). Therefore, inhibition of angiogenesis may represent a promi - Angioplasty (versus non surgical management) for intermittent claudication
Cochrane Systematic Reviews, 9-Mar-2018
- Angioplasty for intracranial artery stenosis
Cochrane Systematic Reviews, 19-Jul-2006
Intracranial artery stenosis causes up to 10% of all ischaemic strokes. The rate of recurrent vascular ischaemic events is very high. Angioplasty with or without stent placement is a feasible procedure to dilate the vessel affected. However, its safety an - Angioplasty versus bare metal stenting for superficial femoral artery lesions
Cochrane Systematic Reviews, 24-Jun-2014
Lower limb peripheral arterial disease (PAD) is a common, important manifestation of systemic atherosclerosis. Stenoses or occlusions in the superficial femoral artery may result in intermittent claudication or even critical ischaemia, which may be treate - Angioplasty versus stenting for iliac artery lesions
Cochrane Systematic Reviews, 1-Dec-2020
Atherosclerosis of the iliac artery may result in a stenosis or occlusion, which is defined as iliac artery occlusive disease. A range of surgical and endovascular treatment options are available. Open surgical procedures have excellent patency rates but - Angioplasty versus stenting for infrapopliteal arterial lesions in chronic limb‐threatening ischaemia
Cochrane Systematic Reviews, 8-Dec-2018
Chronic limb-threatening ischaemia (CLTI) is a manifestation of peripheral arterial disease (PAD) that includes chronic ischaemic rest pain or ischaemic skin lesions, ulcers, or gangrene for longer than two weeks. The severity of the disease depends on th - Angioplasty versus stenting for subclavian artery stenosis
Cochrane Systematic Reviews, 21-Feb-2022
The subclavian arteries are two major arteries of the upper chest, below the collar bone, which come from the arch of the aorta. Endovascular treatment for stenosis of the subclavian arteries includes angioplasty alone, and with stenting. There is insuffi - Angiotensin converting enzyme (ACE) inhibitors versus angiotensin receptor blockers for primary hypertension
Cochrane Systematic Reviews, 29-Aug-2014
Angiotensin converting enzyme inhibitors (ACE inhibitors) and angiotensin receptor blockers (ARBs) are widely prescribed for primary hypertension (systolic blood pressure > 140 mmHg or diastolic blood pressure > 90 mmHg). However, while ACE inhibitors hav - Angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists for preventing the progression of diabetic kidney disease
Cochrane Systematic Reviews, 18-Oct-2006
Angiotensin converting enzyme inhibitors (ACEi) and angiotensin II receptor antagonists (AIIRA) are considered to be equally effective for patients with diabetic kidney disease (DKD), but renal and not mortality outcomes have usually been considered. - Angiotensin converting enzyme inhibitors in normotensive diabetic patients with microalbuminuria
Cochrane Systematic Reviews, 9-Nov-2008
Renal disease is a serious complication of diabetes mellitus. - Angiotensin receptor blockers for heart failure
Cochrane Systematic Reviews, 18-Apr-2012
Chronic heart failure (HF) is a prevalent world-wide. Angiotensin receptor blockers (ARBs) are widely prescribed for chronic HF although their role is controversial. - Angiotensin‐converting enzyme (ACE) inhibitors for proteinuria and microalbuminuria in people with sickle cell disease
Cochrane Systematic Reviews, 21-Dec-2021
Sickle cell disease is a group of disorders characterized by deformation of erythrocytes. Renal damage is a frequent complication in sickle cell disease as a result of long-standing anemia and disturbed circulation through the renal medullary capillaries. - Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for adults with early (stage 1 to 3) non-diabetic chronic kidney disease
Cochrane Systematic Reviews, 29-Aug-2011
Chronic kidney disease (CKD) is a long term condition that occurs as a result of damage to the kidneys. Early recognition of CKD is becoming increasingly common due to widespread laboratory estimated glomerular filtration rate (eGFR) reporting, raised cli - Angiotensin‐converting enzyme inhibitors and angiotensin receptor blockers for preserving residual kidney function in peritoneal dialysis patients
Cochrane Systematic Reviews, 23-Jun-2014
Angiotensin-converting enzyme inhibitors (ACEis) and angiotensin receptor blockers (ARBs) are widely used in peritoneal dialysis (PD) patients, yet controversy exists about their impact on residual kidney function. - Animal derived surfactant extract for treatment of respiratory distress syndrome
Cochrane Systematic Reviews, 15-Apr-2009
Respiratory distress syndrome (RDS) is caused by a deficiency or dysfunction of pulmonary surfactant. A wide variety of surfactant products have been formulated and studied in clinical trials. These include synthetic surfactants and animal derived surfact - Animal derived surfactant extract versus protein free synthetic surfactant for the prevention and treatment of respiratory distress syndrome
Cochrane Systematic Reviews, 24-Aug-2015
A wide variety of surfactant preparations have been developed and tested including synthetic surfactants and surfactants derived from animal sources. Although clinical trials have demonstrated that both synthetic surfactant and animal derived surfactant p - Animal‐assisted therapy for dementia
Cochrane Systematic Reviews, 25-Nov-2019
Dementia is a chronic condition which progressively affects memory and other cognitive functions, social behaviour, and ability to carry out daily activities. To date, no treatment is clearly effective in preventing progression of the disease, and most tr - Ankle brachial index for the diagnosis of lower limb peripheral arterial disease
Cochrane Systematic Reviews, 14-Sep-2016
Peripheral arterial disease (PAD) of the lower limb is common, with prevalence of both symptomatic and asymptomatic disease estimated at 13% in the over 50 age group. Symptomatic PAD affects about 5% of individuals in Western populations between the ages - Antacids for preventing oesophagogastric variceal bleeding and rebleeding in cirrhotic patients
Cochrane Systematic Reviews, 23-Apr-2008
Ruptured gastroesophageal varices are the most severe and frequent cause of gastrointestinal bleeding in cirrhotic patients, leading to death in 5% to 8% of patients during the first 48 hours and oesophagogastric varices account for 60% to 80% of first bl - Antecolic versus retrocolic reconstruction after partial pancreaticoduodenectomy
Cochrane Systematic Reviews, 11-Jan-2022
Pancreatic cancer remains one of the five leading causes of cancer deaths in industrialised nations. For adenocarcinomas in the head of the gland and premalignant lesions, partial pancreaticoduodenectomy represents the standard treatment for resectable tu
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