- Interventions for heartburn in pregnancy
Cochrane Systematic Reviews, 3-Nov-2015
Heartburn is a common symptom in pregnancy affecting up to 80% of women in the third trimester. The reasons for the increase in symptoms in pregnancy are not well understood, but the effects of pregnancy hormones on the lower oesophageal sphincter and gas - Interventions for helping people adhere to compression treatments for venous leg ulceration
Cochrane Systematic Reviews, 1-Mar-2016
Chronic venous ulcer healing is a complex clinical problem that requires intervention from skilled, costly, multidisciplinary wound-care teams. Compression therapy has been shown to help heal venous ulcers and to reduce recurrence. It is not known which i - Interventions for helping people recognise early signs of recurrence in bipolar disorder
Cochrane Systematic Reviews, 1-Nov-2008
Recurrence rates for bipolar disorder are high despite effective treatments with mood stabiliser drugs. Self-help treatments and psychological treatments that teach patients to recognise and manage early warning symptoms and signs (EWS) of impending manic - Interventions for helping to turn term breech babies to head first presentation when using external cephalic version
Cochrane Systematic Reviews, 9-Mar-2016
Breech presentation is associated with increased complications. Turning a breech baby to head first presentation using external cephalic version (ECV) attempts to reduce the chances of breech presentation at birth so as to avoid the adverse effects of bre - Interventions for hereditary haemochromatosis
Cochrane Systematic Reviews, 12-Apr-2017
Hereditary haemochromatosis is a genetic disorder related to proteins involved in iron transport, resulting in iron load and deposition of iron in various tissues of the body. This iron overload leads to complications including liver cirrhosis (and relate - Interventions for hidradenitis suppurativa
Cochrane Systematic Reviews, 27-Feb-2017
Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterised by recurrent painful boils in flexural sites, such as the axillae and groin, that affects about 1% of the population, with onset in early adulthood. - Interventions for hiring, retaining and training district health systems managers in low‐ and middle‐income countries
Cochrane Systematic Reviews, 11-Jul-2013
District managers are playing an increasingly important role in determining the performance of health systems in low- and middle-income countries as a result of decentralization. - Interventions for hirsutism (excluding laser and photoepilation therapy alone)
Cochrane Systematic Reviews, 17-May-2017
Hirsutism occurs in 5% to 10% of women of reproductive age when there is excessive terminal hair growth in androgen-sensitive areas (male pattern). It is a distressing disorder with a major impact on quality of life. The most common cause is polycystic ov - Interventions for HIV‐associated nephropathy
Cochrane Systematic Reviews, 22-Nov-2012
Human immunodeficiency virus-associated nephropathy (HIVAN) is the most common cause of end stage kidney disease (ESKD) in human immunodeficiency virus-1 (HIV-1) serotype patients and it mostly affects patients of African descent. It rapidly progresses to - Interventions for hyperthyroidism pre-pregnancy and during pregnancy
Cochrane Systematic Reviews, 12-Nov-2013
Women with hyperthyroidism in pregnancy have increased risks of miscarriage, stillbirth, preterm birth, and intrauterine growth restriction; and they can develop severe pre-eclampsia or placental abruption. - Interventions for iatrogenic inferior alveolar and lingual nerve injury
Cochrane Systematic Reviews, 15-Apr-2014
Iatrogenic injury of the inferior alveolar or lingual nerve or both is a known complication of oral and maxillofacial surgery procedures. Injury to these two branches of the mandibular division of the trigeminal nerve may result in altered sensation assoc - Interventions for idiopathic intracranial hypertension
Cochrane Systematic Reviews, 3-Aug-2015
Idiopathic intracranial hypertension (IIH) has an estimated incidence of one to three people per 100,000 people per year, and occurs most commonly in obese, young women. IIH is associated with severe morbidity, notably due to a significant threat to sight - Interventions for idiopathic steroid‐resistant nephrotic syndrome in children
Cochrane Systematic Reviews, 21-Nov-2019
The majority of children who present with their first episode of nephrotic syndrome achieve remission with corticosteroid therapy. Children who fail to respond to corticosteroids in the first episode of nephrotic syndrome (initial resistance) or develop r - Interventions for idiopathic toe walking
Cochrane Systematic Reviews, 7-Oct-2019
Idiopathic toe walking (ITW) is an exclusionary diagnosis given to healthy children who persist in walking on their toes after they should typically have achieved a heel-toe gait. The literature discusses conservative and surgical interventions using a va - Interventions for impetigo
Cochrane Systematic Reviews, 9-Jun-2015
Impetigo is a common, superficial bacterial skin infection, which is most frequently encountered in children. There is no generally agreed standard therapy, and guidelines for treatment differ widely. Treatment options include many different oral and topi - Interventions for implementation of thromboprophylaxis in hospitalized patients at risk for venous thromboembolism
Cochrane Systematic Reviews, 13-Apr-2018
Venous thromboembolism (VTE) is a leading cause of morbidity and mortality in hospitalized patients. While numerous randomized controlled trials (RCTs) have shown that the appropriate use of thromboprophylaxis in hospitalized patients at risk for VTE is s - Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia
Cochrane Systematic Reviews, 3-May-2018
Regularly transfused people with sickle cell disease (SCD) and people with thalassaemia (who are transfusion-dependent or non-transfusion-dependent) are at risk of iron overload. Iron overload can lead to iron toxicity in vulnerable organs such as the hea - Interventions for improving adherence to ocular hypotensive therapy
Cochrane Systematic Reviews, 29-Mar-2013
Poor adherence to therapy is a significant healthcare issue, particularly in patients with chronic disease such as open-angle glaucoma. Treatment failure may necessitate unwarranted changes of medications, increased healthcare expenditure and risk to the - Interventions for improving adherence to treatment in patients with high blood pressure in ambulatory settings
Cochrane Systematic Reviews, 12-Aug-2008
Lack of adherence to blood pressure lowering medication is a major reason for poor control of hypertension worldwide. Interventions to improve adherence to antihypertensive medication have been evaluated in randomised trials but it is unclear which interv - Interventions for improving adherence to treatment recommendations in people with type 2 diabetes mellitus
Cochrane Systematic Reviews, 27-Oct-2008
Research suggests adherence to treatment recommendations is low. In type 2 diabetes, which is a chronic condition slowly leading to serious vascular, nephrologic, neurologic and ophthalmological complications, it can be assumed that enhancing adherence to
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