- Inhaled steroids with and without regular formoterol for asthma: serious adverse events
Cochrane Systematic Reviews, 25-Sep-2019
Epidemiological evidence has suggested a link between beta2-agonists and increases in asthma mortality. There has been much debate about whether regular (daily) long-acting beta2-agonists (LABA) are safe when used in combination with inhaled corticosteroi - Inhaled steroids with and without regular salmeterol for asthma: serious adverse events
Cochrane Systematic Reviews, 3-Dec-2018
Epidemiological evidence has suggested a link between use of beta2-agonists and increased asthma mortality. Much debate has surrounded possible causal links for this association, and whether regular (daily) long-acting beta2-agonists (LABAs) are safe, par - Inhaled versus oral steroids for adults with chronic asthma
Cochrane Systematic Reviews, 22-Jan-2001
Steroids are a common treatment of chronic asthma as a maintenance therapy in both developed and developing countries across the world. The cost of inhaled steroids means that in developing countries their availability is limited, leading to poorly contro - Inhaled versus systemic corticosteroids for preventing bronchopulmonary dysplasia in ventilated very low birth weight preterm neonates
Cochrane Systematic Reviews, 17-Oct-2017
Bronchopulmonary dysplasia (BPD) remains an important cause of mortality and morbidity in preterm infants and inflammation plays a significant role in its pathogenesis. The use of inhaled corticosteroids may modulate the inflammatory process without conco - Inhaled versus systemic corticosteroids for the treatment of bronchopulmonary dysplasia in ventilated very low birth weight preterm infants
Cochrane Systematic Reviews, 16-Oct-2017
This is an update of a review published in 2012. A related review "Inhaled versus systemic corticosteroids for preventing bronchopulmonary dysplasia in ventilated very low birth weight preterm neonates" has been updated as well. Bronchopulmonary dysplasia - In‐hospital care pathways for stroke
Cochrane Systematic Reviews, 18-Oct-2004
Stroke care pathways have the potential to promote organised and efficient patient care that is based on best evidence and guidelines, but evidence to support their use is unclear. - Initial arch wires used in orthodontic treatment with fixed appliances
Cochrane Systematic Reviews, 31-Jul-2018
Initial arch wires are the first arch wires to be inserted into the fixed appliance at the beginning of orthodontic treatment and are used mainly for the alignment of teeth by correcting crowding and rotations. With a number of different types of orthodon - Initial management strategies for dyspepsia
Cochrane Systematic Reviews, 23-Jul-2009
This review considers management strategies (combinations of initial investigation and empirical treatments) for dyspeptic patients. Dyspepsia was defined to include both epigastric pain and heartburn. - Injectable gold for rheumatoid arthritis
Cochrane Systematic Reviews, 20-Oct-1997
Gold compounds have been used in several conditions affecting man since the 18th century (tuberculosis, lupus vulgaris, bacterial endocarditis, etc.) however, in the past decade the use of injectable gold for rheumatoid arthritis has markedly declined, an - Injectable local anaesthetic agents for dental anaesthesia
Cochrane Systematic Reviews, 10-Jul-2018
Pain during dental treatment, which is a common fear of patients, can be controlled successfully by local anaesthetic. Several different local anaesthetic formulations and techniques are available to dentists. - Injected corticosteroids for treating plantar heel pain in adults
Cochrane Systematic Reviews, 11-Jun-2017
Plantar heel pain, commonly resulting from plantar fasciitis, often results in significant morbidity. Treatment options include nonsteroidal anti-inflammatory drugs (NSAIDs), orthoses, physical therapy, physical agents (e.g. extracorporeal shock wave ther - Injection allergen immunotherapy for asthma
Cochrane Systematic Reviews, 28-Jun-2010
Allergen specific immunotherapy has long been a controversial treatment for asthma. Although beneficial effects upon clinically relevant outcomes have been demonstrated in randomised controlled trials, there remains a risk of severe and sometimes fatal an - Injection sclerotherapy for varicose veins
Cochrane Systematic Reviews, 10-Dec-2021
Varicose veins are enlarged and tortuous veins, affecting up to one-third of the world's population. They can be a cause of chronic venous insufficiency, which is characterised by oedema, pigmentation, eczema, lipodermatosclerosis, atrophie blanche, and h - Injection therapies for Achilles tendinopathy
Cochrane Systematic Reviews, 21-May-2015
Achilles tendinopathy is a common condition, often with significant functional consequences. As a wide range of injection treatments are available, a review of randomised trials evaluating injection therapies to help inform treatment decisions is warrante - Injection therapy for subacute and chronic low‐back pain
Cochrane Systematic Reviews, 16-Jul-2008
The effectiveness of injection therapy for low-back pain is still debatable. Heterogeneity of target tissue, pharmacological agent and dosage generally found in randomized controlled trials (RCTs) points to the need for clinically valid comparisons in a l - Inositol for depressive disorders
Cochrane Systematic Reviews, 26-Jan-2004
There are a number of effective interventions for the treatment of depression. It is possible that the efficacy of these treatments will be improved further by the use of adjunctive therapies such as inositol. - Inositol for subfertile women with polycystic ovary syndrome
Cochrane Systematic Reviews, 20-Dec-2018
Subfertile women are highly motivated to try different adjunctive therapies to have a baby, and the widespread perception is that dietary supplements such as myo-inositol (MI) and D-chiro-insoitol (DCI) are associated with only benefit, and not with harm. - Inositol in preterm infants at risk for or having respiratory distress syndrome
Cochrane Systematic Reviews, 8-Jul-2019
Inositol is an essential nutrient required by human cells in culture for growth and survival. Inositol promotes maturation of several components of surfactant and may play a critical role in fetal and early neonatal life. A drop in inositol levels in infa - Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome
Cochrane Systematic Reviews, 5-Nov-2020
Cardiogenic shock (CS) and low cardiac output syndrome (LCOS) are potentially life-threatening complications of acute myocardial infarction (AMI), heart failure (HF) or cardiac surgery. While there is solid evidence for the treatment of other cardiovascul - Inpatient versus other settings for detoxification for opioid dependence
Cochrane Systematic Reviews, 24-Jun-2008
There are a complex range of variables that can influence the course and subjective severity of opioid withdrawal. There is a growing evidence for the effectiveness of a range of medically-supported detoxification strategies, but little attention has been
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