- Insulin secretagogues for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at increased risk for the development of type 2 diabetes mellitus
Cochrane Systematic Reviews, 17-Oct-2016
The projected rise in the incidence of type 2 diabetes mellitus (T2DM) could develop into a substantial health problem worldwide. Whether insulin secretagogues (sulphonylureas and meglitinide analogues) are able to prevent or delay T2DM and its associated - Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility
Cochrane Systematic Reviews, 16-Feb-2018
Polycystic ovary syndrome (PCOS) is characterised by infrequent or absent ovulation, and high levels of androgens and insulin (hyperinsulinaemia). Hyperinsulinaemia occurs secondary to insulin resistance and is associated with increased risk of cardiovasc - Integrated community case management of childhood illness in low‐ and middle‐income countries
Cochrane Systematic Reviews,
The leading causes of mortality globally in children younger than five years of age (under-fives), and particularly in the regions of sub-Saharan Africa (SSA) and Southern Asia, in 2018 were infectious diseases, including pneumonia (15%), diarrhoea (8%), - Integrated disease management interventions for patients with chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 8-Oct-2013
In people with chronic obstructive pulmonary disease (COPD) there is considerable variation in symptoms, limitations and well-being, which often complicates medical care. To improve quality of life (QoL) and exercise tolerance, while reducing the number o - Integrated management of childhood illness (IMCI) strategy for children under five
Cochrane Systematic Reviews, 22-Jun-2016
More than 7.5 million children younger than age five living in low- and middle-income countries die every year. The World Health Organization (WHO) developed the integrated management of childhood illness (IMCI) strategy to reduce mortality and morbidity - Integrated versus non-integrated orbital implants for treating anophthalmic sockets
Cochrane Systematic Reviews, 7-Nov-2016
Anophthalmia is the absence of one or both eyes, and it can be congenital (i.e. a birth defect) or acquired later in life. There are two main types of orbital implant: integrated, whereby the implant receives a blood supply from the body that allows for t - Integrating prevention of mother-to-child HIV transmission (PMTCT) programmes with other health services for preventing HIV infection and improving HIV outcomes in developing countries
Cochrane Systematic Reviews, 10-May-2011
Every year nearly 400,000 children are infected with HIV through mother-to-child transmission (MTCT), which is responsible for more than 90% of HIV infections in children. In high-income countries, the MTCT rate is less than 1% through perinatal preventio - Integration of HIV/AIDS services with maternal, neonatal and child health, nutrition, and family planning services
Cochrane Systematic Reviews, 12-Sep-2012
The integration of HIV/AIDS and maternal, neonatal, child health and nutrition services (MNCHN), including family planning (FP) is recognized as a key strategy to reduce maternal and child mortality and control the HIV/AIDS epidemic. However, limited evid - Intense pulsed light (IPL) therapy for the treatment of meibomian gland dysfunction
Cochrane Systematic Reviews, 17-Mar-2020
Meibomian gland dysfunction (MGD) is the major cause of evaporative dry eye disease, which is the more prevalent form of dry eye disease. Intense pulsed light (IPL) therapy, involving treatment of the skin near the eyelids, has emerged as a potential trea - Intensity of continuous renal replacement therapy for acute kidney injury
Cochrane Systematic Reviews, 25-Sep-2016
Acute kidney injury (AKI) is a common condition among patients in intensive care units (ICU), and is associated with substantial morbidity and mortality. Continuous renal replacement therapy (CRRT) is a blood purification technique used to treat the most - Intensity of exercise for the treatment of osteoarthritis
Cochrane Systematic Reviews, 8-Jan-2013
Therapeutic exercise is used as one modality to treat people with osteoarthritis (OA). - Intensive case management for severe mental illness
Cochrane Systematic Reviews, 5-Dec-2016
Intensive Case Management (ICM) is a community-based package of care aiming to provide long-term care for severely mentally ill people who do not require immediate admission. Intensive Case Management evolved from two original community models of care, As - Intensive glucose control versus conventional glucose control for type 1 diabetes mellitus
Cochrane Systematic Reviews, 20-Jun-2016
Clinical guidelines differ regarding their recommended blood glucose targets for patients with type 1 diabetes and recent studies on patients with type 2 diabetes suggest that aiming at very low targets can increase the risk of mortality. - Intensive versus conventional glycaemic control for treating diabetic foot ulcers
Cochrane Systematic Reviews, 12-Jan-2016
The estimated likelihood of lower limb amputation is 10 to 30 times higher amongst people with diabetes compared to those without diabetes. Of all non-traumatic amputations in people with diabetes, 85% are preceded by a foot ulcer. Foot ulceration associa - Interactive computer-based interventions for sexual health promotion
Cochrane Systematic Reviews, 4-Aug-2010
Sexual health promotion is a major public health challenge; there is huge potential for health promotion via technology such as the Internet. - Interactive computer-based interventions for weight loss or weight maintenance in overweight or obese people
Cochrane Systematic Reviews, 28-Jun-2012
The World Health Organization (WHO) estimates that the number of obese or overweight individuals worldwide will increase to 1.5 billion by 2015. Chronic diseases associated with overweight or obesity include diabetes, heart disease, hypertension and strok - Interactive Health Communication Applications for people with chronic disease
Cochrane Systematic Reviews, 22-Oct-2008
Interactive Health Communication Applications (IHCAs) are computer-based, usually web-based, information packages for patients that combine health information with at least one of social support, decision support, or behaviour change support. These are in - Interactive telemedicine: effects on professional practice and health care outcomes
Cochrane Systematic Reviews, 8-Dec-2016
Telemedicine (TM) is the use of telecommunication systems to deliver health care at a distance. It has the potential to improve patient health outcomes, access to health care and reduce healthcare costs. As TM applications continue to evolve it is importa - Intercessory prayer for the alleviation of ill health
Cochrane Systematic Reviews, 4-Jun-2014
Prayer is amongst the oldest and most widespread interventions used with the intention of alleviating illness and promoting good health. Given the significance of this response to illness for a large proportion of the world's population, there has been co - Interconception care for women with a history of gestational diabetes for improving maternal and infant outcomes
Cochrane Systematic Reviews, 23-Aug-2017
Gestational diabetes mellitus (GDM) is associated with adverse health outcomes for mothers and their infants both perinatally and long term. Women with a history of GDM are at risk of recurrence in subsequent pregnancies and may benefit from intervention
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