- Inhaled beta2‐agonists for non‐specific chronic cough in children
Cochrane Systematic Reviews, 20-Jul-2005
The pathophysiology of so called 'cough variant asthma' has not received a great deal of research interest and opinion lies divided as to whether it is really asthma or not. The proponents of cough variant asthma suggest a therapeutic trial of medications - Inhaled bronchodilators for acute chest syndrome in people with sickle cell disease
Cochrane Systematic Reviews, 27-Sep-2016
Bronchodilators are used to treat bronchial hyper-responsiveness in asthma. Bronchial hyper-responsiveness may be a component of acute chest syndrome in people with sickle cell disease. Therefore, bronchodilators may be useful in the treatment of acute ch - Inhaled bronchodilators for cystic fibrosis
Cochrane Systematic Reviews, 11-Feb-2016
Recurrent wheeze and breathlessness are common in people with cystic fibrosis, and bronchodilators are commonly prescribed. Despite their wide-scale and often long-term use, there is limited objective evidence about their efficacy in cystic fibrosis (CF). - Inhaled corticosteroid effects on bone metabolism in asthma and mild chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 21-Jan-2002
Inhaled corticosteroids form the main therapy for asthma, but there is increasing concern about the potential systematic effects of long-term inhaled corticosteroids including their effect on bone metabolism and bone loss. - Inhaled corticosteroids compared to placebo for prevention of exercise induced bronchoconstriction
Cochrane Systematic Reviews, 18-Jul-2007
The pathogenesis of exercise induced bronchoconstriction is likely multifactorial and is not completely understood. Inflammation plays an important role in the pathogenesis of exercise induced bronchoconstriction in asthmatic subjects but the evidence see - Inhaled corticosteroids for bronchiectasis
Cochrane Systematic Reviews, 16-May-2018
Bronchiectasis is being increasingly diagnosed and recognised as an important contributor to chronic lung disease in both adults and children in high- and low-income countries. It is characterised by irreversible dilatation of airways and is generally ass - Inhaled corticosteroids for cystic fibrosis
Cochrane Systematic Reviews, 4-Jul-2019
The reduction of lung inflammation is one of the goals of cystic fibrosis therapy. Inhaled corticosteroids are often used in this respect to treat children and adults with cystic fibrosis. The rationale for this is their potential to reduce lung damage ar - Inhaled corticosteroids for non-specific chronic cough in children
Cochrane Systematic Reviews, 29-Mar-2009
Cough in isolation of other clinical features is known as non-specific cough, which has been defined as non-productive cough in the absence of identifiable respiratory disease or any known aetiology. In children with non-specific cough the possibility of - Inhaled corticosteroids for stable chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 25-Aug-2016
The role of inhaled corticosteroids (ICS) in chronic obstructive pulmonary disease (COPD) has been the subject of much controversy. Major international guidelines recommend selective use of ICS. Recently published meta-analyses have reported conflicting f - Inhaled corticosteroids for subacute and chronic cough in adults
Cochrane Systematic Reviews, 28-Mar-2013
Persistent cough is a common clinical problem. Despite thorough investigation and empirical management, a considerable proportion of those people with subacute and chronic cough have unexplained cough, for which treatment options are limited. While curren - Inhaled corticosteroids for subacute cough in children
Cochrane Systematic Reviews, 11-Dec-2012
Cough is the most common symptom presenting to primary healthcare services. Cough in children is associated with significant morbidity for both children and their parents. While inhaled corticosteroids (ICS) can potentially reduce cough associated with ai - Inhaled corticosteroids for the treatment of COVID‐19
Cochrane Systematic Reviews, 9-Mar-2022
Inhaled corticosteroids are well established for the long-term treatment of inflammatory respiratory diseases such as asthma or chronic obstructive pulmonary disease. They have been investigated for the treatment of coronavirus disease 2019 (COVID-19). Th - Inhaled corticosteroids in children with persistent asthma: dose‐response effects on growth
Cochrane Systematic Reviews, 16-Jul-2014
Inhaled corticosteroids (ICS) are the first-line treatment for children with persistent asthma. Their potential for growth suppression remains a matter of concern for parents and physicians. - Inhaled corticosteroids in children with persistent asthma: effects of different drugs and delivery devices on growth
Cochrane Systematic Reviews, 10-Jun-2019
Inhaled corticosteroids (ICS) are the most effective treatment for children with persistent asthma. Although treatment with ICS is generally considered to be safe in children, the potential adverse effects of these drugs on growth remains a matter of conc - Inhaled corticosteroids in children with persistent asthma: effects on growth
Cochrane Systematic Reviews, 16-Jul-2014
Treatment guidelines for asthma recommend inhaled corticosteroids (ICS) as first-line therapy for children with persistent asthma. Although ICS treatment is generally considered safe in children, the potential systemic adverse effects related to regular u - Inhaled corticosteroids versus long‐acting beta2‐agonists for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 7-Dec-2011
Long-acting beta2-agonists and inhaled corticosteroids can be used as maintenance therapy by patients with moderate to severe chronic obstructive pulmonary disease. These interventions are often taken together in a combination inhaler. However, the relati - Inhaled corticosteroids versus sodium cromoglycate in children and adults with asthma
Cochrane Systematic Reviews, 19-Apr-2006
Inhaled corticosteroids (ICS) and sodium cromoglycate (SCG) have become established as effective controller medications for children and adults with asthma, but their relative efficacy is not clear. - Inhaled corticosteroids with combination inhaled long‐acting beta2‐agonists and long‐acting muscarinic antagonists for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 10-Nov-2016
Management of chronic obstructive pulmonary disease (COPD) commonly involves long-acting bronchodilators including beta-agonists (LABA) and muscarinic antagonists (LAMA). In individuals with persistent symptoms or frequent exacerbations, inhaled corticost - Inhaled cromones for prolonged non-specific cough in children
Cochrane Systematic Reviews, 20-Jul-2010
Non-specific cough is defined as non-productive cough in the absence of identifiable respiratory disease or known aetiology. It is commonly seen in paediatric practice. These children are treated with a variety of therapies including inhaled cromones. - Inhaled hyperosmolar agents for bronchiectasis
Cochrane Systematic Reviews, 9-May-2014
Mucus retention in the lungs is a prominent feature of bronchiectasis. The stagnant mucus becomes chronically colonised with bacteria, which elicit a host neutrophilic response. This fails to eliminate the bacteria, and the large concentration of host-der
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