- Immunotherapy for idiopathic lumbosacral plexopathy
Cochrane Systematic Reviews, 21-Dec-2013
Idiopathic lumbosacral plexopathy (ILSP), also called lumbosacral plexitis or non-diabetic lumbosacral (radiculo)plexus neuropathy is a rare clinical entity. The core features are (sub)acute, severe, asymmetrical leg pain, followed by asymmetrical multifo - Immunotherapy for IgM anti‐myelin‐associated glycoprotein paraprotein‐associated peripheral neuropathies
Cochrane Systematic Reviews, 4-Oct-2016
Serum monoclonal anti-myelin-associated glycoprotein (anti-MAG) antibodies may be pathogenic in some people with immunoglobulin M (IgM) paraprotein and demyelinating neuropathy. Immunotherapies aimed at reducing the level of these antibodies might be expe - Immunotherapy for metastatic renal cell carcinoma
Cochrane Systematic Reviews, 15-May-2017
Since the mid-2000s, the field of metastatic renal cell carcinoma (mRCC) has experienced a paradigm shift from non-specific therapy with broad-acting cytokines to specific regimens, which directly target the cancer, the tumour microenvironment, or both. - Immunotherapy for recurrent miscarriage
Cochrane Systematic Reviews, 21-Oct-2014
Because immunological aberrations might be the cause of miscarriage in some women, several immunotherapies have been used to treat women with otherwise unexplained recurrent pregnancy loss. - Impact of diagnostic strategies for tuberculosis using lateral flow urine lipoarabinomannan assay in people living with HIV
Cochrane Systematic Reviews, 20-Aug-2021
Tuberculosis is the primary cause of hospital admission in people living with HIV, and the likelihood of death in the hospital is unacceptably high. The Alere Determine TB LAM Ag test (AlereLAM) is a point-of-care test and the only lateral flow lipoarabin - Impact of Haemophilus influenzae type B (Hib) and viral influenza vaccinations in pregnancy for improving maternal, neonatal and infant health outcomes
Cochrane Systematic Reviews, 5-Jun-2015
Infections during pregnancy confers increased risk of maternal and perinatal morbidity and mortality. However, the case for advocating Haemophilus influenzae type B (Hib) and viral Influenza vaccinations in pregnancy is still debatable. - Impact of institutional smoking bans on reducing harms and secondhand smoke exposure
Cochrane Systematic Reviews, 25-May-2016
Smoking bans or restrictions can assist in eliminating nonsmokers' exposure to the dangers of secondhand smoke and can reduce tobacco consumption amongst smokers themselves. Evidence exists identifying the impact of tobacco control regulations and interve - Impact of medication reconciliation for improving transitions of care
Cochrane Systematic Reviews, 23-Aug-2018
Transitional care provides for the continuity of care as patients move between different stages and settings of care. Medication discrepancies arising at care transitions have been reported as prevalent and are linked with adverse drug events (ADEs) (e.g. - Impact of morphine, fentanyl, oxycodone or codeine on patient consciousness, appetite and thirst when used to treat cancer pain
Cochrane Systematic Reviews, 28-May-2019
There is increasing focus on providing high quality care for people at the end of life, irrespective of disease or cause, and in all settings. In the last ten years the use of care pathways to aid those treating patients at the end of life has become comm - Impact of public release of performance data on the behaviour of healthcare consumers and providers
Cochrane Systematic Reviews, 6-Sep-2018
It is becoming increasingly common to publish information about the quality and performance of healthcare organisations and individual professionals. However, we do not know how this information is used, or the extent to which such reporting leads to qual - Impact of the diagnostic test Xpert MTB/RIF on patient outcomes for tuberculosis
Cochrane Systematic Reviews, 6-May-2021
The World Health Organization (WHO) recommends Xpert MTB/RIF in place of smear microscopy to diagnose tuberculosis (TB), and many countries have adopted it into their diagnostic algorithms. However, it is not clear whether the greater accuracy of the test - Impact of tobacco advertising and promotion on increasing adolescent smoking behaviours
Cochrane Systematic Reviews, 5-Oct-2011
The tobacco industry denies that their marketing is targeted at young nonsmokers, but it seems more probable that tobacco advertising and promotion influences the attitudes of nonsmoking adolescents, and makes them more likely to try smoking. - Implantable cardiac defibrillators for people with non‐ischaemic cardiomyopathy
Cochrane Systematic Reviews, 8-Dec-2018
There is evidence that implantable cardioverter-defibrillator (ICD) for primary prevention in people with an ischaemic cardiomyopathy improves survival rate. The evidence supporting this intervention in people with non-ischaemic cardiomyopathy is not as d - Implantable defibrillators versus medical therapy for cardiac channelopathies
Cochrane Systematic Reviews, 7-Oct-2015
Sudden cardiac death is a significant cause of mortality in both the US and globally. However, 5% to 15% of people with sudden cardiac death have no structural abnormalities, and most of these events are attributed to underlying cardiac ion channelopathie - Implantable loop recorder versus conventional diagnostic workup for unexplained recurrent syncope
Cochrane Systematic Reviews, 19-Apr-2016
The most recent syncope guideline recommends that implantable loop recorders (ILRs) are implanted in the early phase of evaluation of people with recurrent syncope of uncertain origin in the absence of high-risk criteria, and in high-risk patients after a - Implantable miniature telescope (IMT) for vision loss due to end‐stage age‐related macular degeneration
Cochrane Systematic Reviews, 30-May-2018
Age-related macular degeneration (AMD) causes progressive and irreversible damage to the retina, resulting in loss of central vision. AMD is the third leading cause of irreversible visual impairment worldwide and the leading cause of blindness in industri - Implanted spinal neuromodulation interventions for chronic pain in adults
Cochrane Systematic Reviews, 2-Dec-2021
Implanted spinal neuromodulation (SNMD) techniques are used in the treatment of refractory chronic pain. They involve the implantation of electrodes around the spinal cord (spinal cord stimulation (SCS)) or dorsal root ganglion (dorsal root ganglion stimu - Implementation interventions to promote the uptake of evidence‐based practices in stroke rehabilitation
Cochrane Systematic Reviews, 15-Oct-2020
Rehabilitation based upon research evidence gives stroke survivors the best chance of recovery. There is substantial research to guide practice in stroke rehabilitation, yet uptake of evidence by healthcare professionals is typically slow and patients oft - Implementation of treatment guidelines for specialist mental health care
Cochrane Systematic Reviews, 15-Dec-2016
A huge gap exists between the production of evidence and its uptake in clinical practice settings. To fill this gap, treatment guidelines, based on explicit assessments of the evidence base, are commonly used in several fields of psychiatry, including sch - Implementation strategies for health systems in low‐income countries: an overview of systematic reviews
Cochrane Systematic Reviews, 12-Sep-2017
A key function of health systems is implementing interventions to improve health, but coverage of essential health interventions remains low in low-income countries. Implementing interventions can be challenging, particularly if it entails complex changes
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