- Hydroxyurea (hydroxycarbamide) for transfusion‐dependent β‐thalassaemia
Cochrane Systematic Reviews, 16-Mar-2019
Hydroxyurea (hydroxycarbamide) promotes the production of foetal haemoglobin (HbF) by reactivating gamma-genes. Evidence has shown clinical benefits of hydroxyurea in people with sickle cell anemia; however, only a few studies have assessed this treatment - Hydroxyurea for reducing blood transfusion in non-transfusion dependent beta thalassaemias
Cochrane Systematic Reviews, 8-Aug-2016
Non-transfusion dependent beta thalassaemia is a subset of inherited haemoglobin disorders characterised by reduced production of the beta globin chain of the haemoglobin molecule leading to anaemia of varying severity. Although blood transfusion is not a - Hydroxyzine for generalised anxiety disorder
Cochrane Systematic Reviews, 9-Nov-2010
Generalised anxiety disorder (GAD) is a common chronic long-term psychiatric disorder, particularly frequent in primary care. There are several treatment options available, both non-pharmacological (i.e. cognitive behavioral therapy) and pharmacological. - Hygiene and emollient interventions for maintaining skin integrity in older people in hospital and residential care settings
Cochrane Systematic Reviews, 23-Jan-2020
Ageing has a degenerative effect on the skin, leaving it more vulnerable to damage. Hygiene and emollient interventions may help maintain skin integrity in older people in hospital and residential care settings; however, at present, most care is based on - Hyperbaric oxygen as an adjuvant treatment for malignant otitis externa
Cochrane Systematic Reviews, 31-May-2013
Malignant, or necrotising, otitis externa is a potentially fatal infection of the external ear canal and surrounding soft tissue and bone. It may be complicated by involvement of cranial nerves, principally the facial nerves and the contents of the jugula - Hyperbaric oxygen for carbon monoxide poisoning
Cochrane Systematic Reviews, 13-Apr-2011
Poisoning with carbon monoxide (CO) remains an important cause of accidental and intentional injury worldwide. Several unblinded non-randomized trials have suggested that the use of hyperbaric oxygen (HBO) prevents the development of neurological sequelae - Hyperbaric oxygen for idiopathic sudden sensorineural hearing loss and tinnitus
Cochrane Systematic Reviews, 17-Oct-2012
This is an update of a Cochrane Review first published in The Cochrane Library in Issue 1, 2005 and previously updated in 2007 and 2009. - Hyperbaric oxygen therapy for acute coronary syndrome
Cochrane Systematic Reviews, 23-Jul-2015
Acute coronary syndrome (ACS), includes acute myocardial infarction and unstable angina, is common and may prove fatal. Hyperbaric oxygen therapy (HBOT) will improve oxygen supply to the threatened heart and may reduce the volume of heart muscle that peri - Hyperbaric oxygen therapy for acute ischaemic stroke
Cochrane Systematic Reviews, 12-Nov-2014
Most cases of stroke are caused by impairment of blood flow to the brain (ischaemia), which results in a reduction in available oxygen and subsequent cell death. It has been postulated that hyperbaric oxygen therapy (HBOT) may reduce the volume of brain t - Hyperbaric oxygen therapy for Bell's palsy
Cochrane Systematic Reviews, 15-Feb-2012
Bell's palsy is an idiopathic, acute unilateral facial weakness that evolves rapidly and is maximal within two days. Moderate ear discomfort, sensitivity to sound and reduced tearing may occur. - Hyperbaric oxygen therapy for chronic wounds
Cochrane Systematic Reviews, 24-Jun-2015
Chronic wounds are common and present a health problem with significant effect on quality of life. Various pathologies may cause tissue breakdown, including poor blood supply resulting in inadequate oxygenation of the wound bed. Hyperbaric oxygen therapy - Hyperbaric oxygen therapy for delayed onset muscle soreness and closed soft tissue injury
Cochrane Systematic Reviews, 19-Oct-2005
Soft tissue injuries (including muscle damage after unaccustomed exercise) are common and are often associated with athletic activity. Hyperbaric oxygen therapy (HBOT) is the therapeutic administration of 100% oxygen at environmental pressures greater tha - Hyperbaric oxygen therapy for late radiation tissue injury
Cochrane Systematic Reviews, 28-Apr-2016
Cancer is a significant global health problem. Radiotherapy is a treatment for many cancers and about 50% of people having radiotherapy will be long-term survivors. Some will experience late radiation tissue injury (LRTI) developing months or years later. - Hyperbaric oxygen therapy for multiple sclerosis
Cochrane Systematic Reviews, 26-Jan-2004
Multiple Sclerosis (MS) is a chronic, recurrent and progressive illness with no cure. On the basis of speculative pathophysiology, it has been suggested that Hyperbaric Oxygen Therapy (HBOT) may slow or reverse the progress of the disease. - Hyperbaric oxygen therapy for people with autism spectrum disorder (ASD)
Cochrane Systematic Reviews, 13-Oct-2016
The rising prevalence of autism spectrum disorder (ASD) has increased the need for evidence-based treatments to lessen the impact of symptoms. Presently, no therapies are available to effectively treat individuals with all of the symptoms of this disorder - Hyperbaric oxygen therapy for promoting fracture healing and treating fracture non-union
Cochrane Systematic Reviews, 2-Oct-2012
Hyperbaric oxygen therapy (HBOT) consists of intermittently administering 100% oxygen at pressures greater than one atmosphere absolute (ATA) in a pressure vessel. This technology has been used to treat a variety of diseases and has been described as help - Hyperbaric oxygen therapy for the adjunctive treatment of traumatic brain injury
Cochrane Systematic Reviews, 19-Nov-2012
Traumatic brain injury is a common health problem with significant effect on quality of life. Each year in the USA approximately 0.56% of the population suffer a head injury, with a case fatality rate of about 40% for severe injuries. These account for a - Hyperbaric oxygen therapy for thermal burns
Cochrane Systematic Reviews, 19-Apr-2004
Hyperbaric oxygen therapy (HBOT) consists of intermittently administering 100% oxygen at pressures greater than 1 atmosphere in a pressure vessel. This technology has been used to treat a variety of disease states and has been described as helping patient - Hyperbaric oxygen therapy for treating acute surgical and traumatic wounds
Cochrane Systematic Reviews, 6-Dec-2013
Hyperbaric oxygen therapy (HBOT) is used as a treatment for acute wounds (such as those arising from surgery and trauma). However, the effects of HBOT on wound healing are unclear. - Hyperbaric oxygen therapy for vascular dementia
Cochrane Systematic Reviews, 7-Jun-2012
Hyperbaric oxygen therapy (HBOT) has been used to treat a variety of conditions and has shown possible efficacy for treating vascular dementia (VaD) in experimental and preliminary clinical studies.
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