- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Chronic heart failure (HF) is a growing global health challenge. People with HF experience substantial burden that includes low exercise tolerance, poor health-related quality of life (HRQoL), increased risk of mortality and hospital admission, and high h - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Morbidity in patients with chronic heart failure is high, and this predisposes them to thrombotic complications, including stroke and thromboembolism, which in turn contribute to high mortality. Oral anticoagulants (e.g. warfarin) and antiplatelet agents - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This is an update of the review on 'Percutaneous transluminal rotational atherectomy for coronary artery disease' first published in The Cochrane Library Issue 4, 2003. Percutaneous transluminal coronary rotational atherectomy (PTCRA) debulks atherosclero - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Elevated plasma levels of the amino acid homocysteine (hyperhomocysteinaemia) are associated with narrowing or blocking of the arteries (atherosclerosis). Treatment to lower homocysteine levels has been shown to be both effective and cheap in healthy volu - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Evidence for the effectiveness of nutritional supplements containing protein and energy, often prescribed for older people, is limited. Malnutrition is more common in this age group and deterioration of nutritional status can occur during illness. It is i - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
As international healthcare policy has moved away from treating people with severe mental illness in large inpatient psychiatric institutions, beds for people with acute psychiatric disorders are being established in specialised psychiatric units in gener - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
The treatment of brain metastasis is generally palliative since most patients have uncontrollable systemic cancer. Historically, whole brain radiation therapy (WBRT) has been the treatment of choice, although more recently focused radiation therapy e.g. s - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Considerable controversy exists as to whether any benefit of doxorubicin-based combination chemotherapy outweighs increased toxic effects, inconvenience, and additional costs, compared to single-agent doxorubicin. There is substantial variation in clinica - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Invasive cervical carcinoma is preceded by a precancerous phase, cervical intra-epithelial neoplasia (CIN), which can be detected on cervical smears and confirmed by colposcopy and biopsy. Moderate and severe cases of intra-epithelial neoplasia (CIN2 and - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Mistletoe extracts are commonly used in cancer patients. It is claimed that they improve survival and quality of life (QOL) in cancer patients. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
The purpose of low-vision rehabilitation is to allow people to resume or to continue to perform daily living tasks, with reading being one of the most important. This is achieved by providing appropriate optical devices and special training in the use of - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Surgery performed to improve or replace the function of the diseased urinary bladder has been carried out for over a century. Main reasons for improving or replacing the function of the urinary bladder are bladder cancer, neurogenic bladder dysfunction, d - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
It is suggested that oestrogen may promote changes in cervical favourability with minimal effect on uterine activity and could be used to induce labour or prime the cervix. A variety of oestrogen preparations (infusions, gels, creams and tablets) and rout - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Gestational diabetes (GDM) affects 3% to 6% of all pregnancies. Women are often intensively managed with increased obstetric monitoring, dietary regulation, and insulin. However, there has been no sound evidence base to support intensive treatment. The ke - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Osteoporosis is an abnormal reduction in bone mass and bone deterioration leading to increased fracture risk. Etidronate belongs to the bisphosphonate class of drugs which act to inhibit bone resorption by interfering with the activity of osteoclasts. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Antenatal maternal glucose administration has been suggested to improve the efficiency of antepartum fetal heart rate testing. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Studies have reported high tumour response rates for platinum-containing regimens in the treatment of women with metastatic breast cancer. Most of these studies were conducted prior to the 'intrinsic subtype' era, and did not specifically focus on metasta - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Constraints on resources and time often render treatments for anxiety such as psychological interventions impracticable. While synthetic anxiolytic drugs are effective, they are often burdened with adverse events. Other options which are effective and saf - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Bipolar disorder is a common recurrent illness with high levels of chronicity. Previous trials have suggested that the anticonvulsant topiramate may be efficacious in bipolar disorder. This is an update of a previous Cochrane review (last published 2006) - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Psychotherapeutic approaches, mainly cognitive behavior therapy, and antidepressant medication are the two treatment modalities that have received most support in controlled outcome studies of bulimia nervosa.
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