- Antiepileptic drugs for the primary and secondary prevention of seizures after stroke
Cochrane Systematic Reviews, 21-Jan-2014
This is an updated version of the original Cochrane review published in 2010, Issue 1. Seizures after stroke are an important clinical problem, and they may be associated with poor outcome. The effects of antiepileptic drugs for the primary and secondary - Antiepileptic drugs for the primary and secondary prevention of seizures after subarachnoid haemorrhage
Cochrane Systematic Reviews, 29-May-2013
Subarachnoid haemorrhage may result in seizures both acutely and in the longer term. The use of antiepileptic drugs (AEDs) in the primary and secondary prevention of seizures after subarachnoid haemorrhage is uncertain, and there is currently no consensus - Antiepileptic drugs for treating seizures in adults with brain tumours
Cochrane Systematic Reviews, 4-Jul-2011
Seizures are a common symptom of brain tumours. The mainstay of treatment for seizures is medical therapy with antiepileptic drugs. - Antiepileptics other than gabapentin, pregabalin, topiramate, and valproate for the prophylaxis of episodic migraine in adults
Cochrane Systematic Reviews, 1-Jul-2016
Some antiepileptic drugs but not others are useful in clinical practice for the prophylaxis of migraine. This might be explained by the variety of actions of these drugs in the central nervous system. The present review is part of an update of a Cochrane - Antifibrinolytic agents for reducing blood loss in scoliosis surgery in children
Cochrane Systematic Reviews, 9-Sep-2016
This is an updated version of the original Cochrane review first published in 2008. Scoliosis surgery is often associated with substantial blood loss and potentially detrimental effects in children. Antifibrinolytic agents are often used to reduce periope - Antifibrinolytic drugs for acute traumatic injury
Cochrane Systematic Reviews, 22-May-2015
Uncontrolled bleeding is an important cause of death in trauma victims. Antifibrinolytic treatment has been shown to reduce blood loss following surgery and may also be effective in reducing blood loss following trauma. - Antifibrinolytic drugs for treating primary postpartum haemorrhage
Cochrane Systematic Reviews, 20-Feb-2018
Postpartum haemorrhage (PPH) - heaving bleeding within the first 24 hours after giving birth - is one of the main causes of death of women after childbirth. Antifibrinolytics, primarily tranexamic acid (TXA), have been shown to reduce bleeding in surgery - Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage
Cochrane Systematic Reviews, 6-Sep-2013
Rebleeding is an important cause of death and disability in people with aneurysmal subarachnoid haemorrhage. Rebleeding is probably related to dissolution of the blood clot at the site of aneurysm rupture by natural fibrinolytic activity. This review is a - Antifibrinolytic therapy for preventing oral bleeding in people on anticoagulants undergoing minor oral surgery or dental extractions
Cochrane Systematic Reviews, 28-Jun-2018
Individuals on continuous treatment with vitamin K antagonists (VKAs) or direct oral anticoagulants (DOACs) are at increased risk of bleeding complications during and after oral or dental procedures. Anticoagulant treatment is preferably continued at the - Antifungal agents for preventing fungal infections in solid organ transplant recipients
Cochrane Systematic Reviews, 12-May-2009
Invasive fungal infections (IFIs) are important causes of morbidity and mortality in solid organ transplant recipients. - Anti-GD2 antibody-containing immunotherapy postconsolidation therapy for people with high-risk neuroblastoma treated with autologous haematopoietic stem cell transplantation
Cochrane Systematic Reviews, 16-Apr-2019
Neuroblastoma is a rare malignant disease that primarily affects children. The tumours mainly develop in the adrenal medullary tissue, and an abdominal mass is the most common presentation. High-risk disease is characterised by metastasis and other primar - Antiglucocorticoid and related treatments for psychosis
Cochrane Systematic Reviews, 16-Dec-2015
Hypothalamic-pituitary-adrenal (HPA) axis dysregulation has been implicated in the development and relapse of psychotic disorders. Elevated cortisol secretion has been positively linked with symptom severity in people with psychosis. Antiglucocorticoid an - Antiglucocorticoid treatments for mood disorders
Cochrane Systematic Reviews, 4-Dec-2015
Antiglucocorticoids may have antidepressant effects and have been reported to be efficacious in the treatment of severe psychiatric disorders. The efficacy and safety of antiglucocorticoid treatments for mood disorders is the subject of this systematic re - Anti-histamines for prolonged non-specific cough in children
Cochrane Systematic Reviews, 19-Nov-2009
Non-specific cough is defined as non-productive cough in the absence of identifiable respiratory disease or known aetiology. It is commonly seen in paediatric practice. These children are treated with a variety of therapies including anti-histamines. Also - Antihistamines for the common cold
Cochrane Systematic Reviews, 23-Nov-2015
The common cold is an upper respiratory tract infection, most commonly caused by a rhinovirus. It affects people of all age groups and although in most cases it is self limiting, the common cold still causes significant morbidity. Antihistamines are commo - Antihistamines for the common cold
Cochrane Systematic Reviews, 21-Jul-2009
Although antihistamines are prescribed in large quantities for the common cold, there is little evidence as to whether these drugs are effective. - Antihistamines used in addition to topical nasal steroids for intermittent and persistent allergic rhinitis in children
Cochrane Systematic Reviews, 14-Jun-2010
Allergic rhinitis is a very common chronic illness affecting 10% to 40% of children worldwide and its prevalence among children has significantly increased over the last two decades. Prevalence and severity are related to age, with children of school age - Antihypertensive agents for preventing diabetic kidney disease
Cochrane Systematic Reviews, 20-Aug-2013
Various blood pressure-lowering agents, and particularly inhibitors of the renin-angiotensin system (RAS), are widely used for people with diabetes to prevent the onset of diabetic kidney disease (DKD) and adverse cardiovascular outcomes. This is an updat - Antihypertensive drug therapy for mild to moderate hypertension during pregnancy
Cochrane Systematic Reviews, 26-Sep-2018
Antihypertensive drugs are often used in the belief that lowering blood pressure will prevent progression to more severe disease, and thereby improve pregnancy outcome. This Cochrane Review is an updated review, first published in 2001 and subsequently up - Anti-hypertensive drugs as disease-modifying agents for Parkinson's disease: evidence from observational studies and clinical trials
Cochrane Systematic Reviews, 20-Sep-2011
Current treatment for Parkinson's disease (PD) is focused on relieving symptoms, at present there is nothing that is widely accepted to halt or slow disease progression. Potential neuroprotective or disease modifying agents have been identified from precl
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