- Glucocorticoid replacement regimens for treating congenital adrenal hyperplasia
Cochrane Systematic Reviews, 19-Mar-2020
Congenital adrenal hyperplasia (CAH) is an autosomal recessive condition which leads to glucocorticoid deficiency and is the most common cause of adrenal insufficiency in children. In over 90% of cases, 21-hydroxylase enzyme deficiency is found which is c - Glucocorticoid supplementation during ovarian stimulation for IVF or ICSI
Cochrane Systematic Reviews, 27-Mar-2017
Ovarian response to stimulation during in-vitro fertilisation (IVF) and intra-cytoplasmic sperm injection (ICSI) plays an important role in determining live birth rates. Adjuvant treatments during ovarian stimulation that have different modes of action ha - Glucocorticoid with cyclophosphamide for oral paraquat poisoning
Cochrane Systematic Reviews, 30-Jun-2021
This an update of a Cochrane Review. - Glucocorticoids for acute viral bronchiolitis in infants and young children
Cochrane Systematic Reviews, 4-Jun-2013
Previous systematic reviews have not shown clear benefit of glucocorticoids for acute viral bronchiolitis, but their use remains considerable. Recent large trials add substantially to current evidence and suggest novel glucocorticoid-including treatment a - Glucocorticoids for croup in children
Cochrane Systematic Reviews, 22-Aug-2018
Glucocorticoids are commonly used for croup in children. This is an update of a Cochrane Review published in 1999 and previously updated in 2004 and 2011. - Glucocorticoids for the treatment of anaphylaxis
Cochrane Systematic Reviews, 18-Apr-2012
Anaphylaxis is a serious hypersensitivity reaction that is rapid in onset and may result in death. Anaphylaxis guidelines recommend glucocorticoids for the treatment of people experiencing anaphylaxis. - Glucocorticosteroid‐free versus glucocorticosteroid‐containing immunosuppression for liver transplanted patients
Cochrane Systematic Reviews, 9-Apr-2018
Liver transplantation is an established treatment option for end-stage liver failure. Now that newer, more potent immunosuppressants have been developed, glucocorticosteroids may no longer be needed and their removal may prevent adverse effects. - Glucocorticosteroids for infants with biliary atresia following Kasai portoenterostomy
Cochrane Systematic Reviews, 14-May-2018
Biliary atresia is a life-threatening disease characterised by progressive destruction of both intra- and extra-hepatic biliary ducts. The mainstay of treatment is Kasai portoenterostomy, as soon as the disease has been confirmed. Glucocorticosteroids are - Glucocorticosteroids for people with alcoholic hepatitis
Cochrane Systematic Reviews, 9-Apr-2019
Alcoholic hepatitis is a form of alcoholic liver disease characterised by steatosis, necroinflammation, fibrosis, and complications to the liver. Typically, alcoholic hepatitis presents in people between 40 and 50 years of age. Alcoholic hepatitis can be - Glucocorticosteroids for primary biliary cirrhosis
Cochrane Systematic Reviews, 22-Sep-2008
Primary biliary cirrhosis is a chronic progressive cholestatic liver disease of presumed autoimmune etiology, characterised by the destruction of small intrahepatic bile ducts and the eventual development of cirrhosis and liver failure. Its progression ma - Glucocorticosteroids for primary sclerosing cholangitis
Cochrane Systematic Reviews, 20-Jan-2010
Primary sclerosing cholangitis is a chronic cholestatic disease of intrahepatic and extrahepatic biliary ducts, characterised by chronic periductal inflammation and sclerosis of the ducts, which results in segmental stenoses of bile ducts, cholestasis, fi - Glucocorticosteroids for viral hepatitis C
Cochrane Systematic Reviews, 19-Apr-2004
Hepatitis C virus may cause liver inflammation and fibrosis. It is not known whether glucocorticosteroids are beneficial or harmful for patients with hepatitis C infection. - Glucosamine therapy for treating osteoarthritis
Cochrane Systematic Reviews, 20-Apr-2005
Osteoarthritis (OA) is a common form of arthritis and is often associated with significant disability and impaired quality of life. This is an update of a Cochrane review first published in 2001 and previously updated in 2005. - Glucose targets for preventing diabetic kidney disease and its progression
Cochrane Systematic Reviews, 8-Jun-2017
Diabetes is the leading cause of end-stage kidney disease (ESKD) around the world. Blood pressure lowering and glucose control are used to reduce diabetes-associated disability including kidney failure. However there is a lack of an overall evidence summa - Glucose‐lowering agents for treating pre‐existing and new‐onset diabetes in kidney transplant recipients
Cochrane Systematic Reviews, 30-Jul-2020
Kidney transplantation is the preferred management for patients with end-stage kidney disease (ESKD). However, it is often complicated by worsening or new-onset diabetes. The safety and efficacy of glucose-lowering agents after kidney transplantation is l - Glutamatergic drugs for schizophrenia
Cochrane Systematic Reviews, 31-Jan-2013
It has been shown that central nervous system dopamine can play a major role in the pathophysiology of schizophrenia. Brain glutamate is thought to mediate symptoms in schizophrenia due to the influence of glutamate neurons on the dopaminergic transmissio - Glutamine for induction of remission in Crohn's disease
Cochrane Systematic Reviews, 8-Feb-2016
Crohn's disease is a chronic relapsing condition of the alimentary tract with a high morbidity secondary to bowel inflammation. Glutamine plays a key role in maintaining the integrity of the intestinal mucosa and has been shown to reduce inflammation and - Glutamine supplementation for critically ill adults
Cochrane Systematic Reviews, 9-Sep-2014
Glutamine is a non-essential amino acid which is abundant in the healthy human body. There are studies reporting that plasma glutamine levels are reduced in patients with critical illness or following major surgery, suggesting that glutamine may be a cond - Glutamine supplementation for young infants with severe gastrointestinal disease
Cochrane Systematic Reviews, 15-Dec-2014
Endogenous glutamine biosynthesis may be insufficient to meet the needs of people with severe gastrointestinal disease. Results from studies using experimental animal models of gastrointestinal disease have suggested that glutamine supplementation improve - Glutamine supplementation to prevent morbidity and mortality in preterm infants
Cochrane Systematic Reviews, 18-Apr-2016
Glutamine is a conditionally essential amino acid. Endogenous biosynthesis may be insufficient for tissue needs in states of metabolic stress. Evidence exists that glutamine supplementation improves clinical outcomes in critically ill adults. It has been
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