- Gemcitabine for unresectable, locally advanced or metastatic bladder cancer
Cochrane Systematic Reviews, 1-Mar-2011
The prognosis for unresectable, locally advanced or metastatic transitional cell carcinoma of the bladder is poor with most patients succumbing to their disease within 2 to 3 years. Clinical management at this stage of the disease is palliative with syste - Gemcitabine‐based chemotherapy for advanced biliary tract carcinomas
Cochrane Systematic Reviews, 6-Apr-2018
Biliary tract cancers are a group of rare heterogeneous malignant tumours. They include intrahepatic and extrahepatic cholangiocarcinomas, gallbladder carcinomas, and ampullary carcinomas. Surgery remains the optimal modality of therapy leading to long-te - Gene therapy for haemophilia
Cochrane Systematic Reviews, 28-Apr-2020
Haemophilia is a genetic disorder characterized by spontaneous or provoked, often uncontrolled, bleeding into joints, muscles and other soft tissues. Current methods of treatment are expensive, challenging and involve regular administration of clotting fa - Gene therapy for peripheral arterial disease
Cochrane Systematic Reviews, 31-Oct-2018
Peripheral arterial disease (PAD), caused by narrowing of the arteries in the limbs, is increasing in incidence and prevalence as our population is ageing and as diabetes is becoming more prevalent. PAD can cause pain in the limbs while walking, known as - Gene therapy for sickle cell disease
Cochrane Systematic Reviews, 30-Nov-2020
Sickle cell disease encompasses a group of genetic disorders characterized by the presence of at least one hemoglobin S (Hb S) allele, and a second abnormal allele that could allow abnormal haemoglobin polymerisation leading to a symptomatic disorder. - General health checks in adults for reducing morbidity and mortality from disease
Cochrane Systematic Reviews, 31-Jan-2019
General health checks are common elements of health care in some countries. They aim to detect disease and risk factors for disease with the purpose of reducing morbidity and mortality. Most of the commonly used individual screening tests offered in gener - General physical health advice for people with serious mental illness
Cochrane Systematic Reviews, 28-Mar-2014
There is currently much focus on provision of general physical health advice to people with serious mental illness and there has been increasing pressure for services to take responsibility for providing this. - Genetic testing for prevention of severe drug-induced skin rash
Cochrane Systematic Reviews, 15-Jul-2019
Drug-induced skin reactions present with a range of clinical symptoms, from mild maculopapular skin rashes to potentially fatal blistering skin rashes — such as Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) — which may result in death - Genital ulcer disease treatment for reducing sexual acquisition of HIV
Cochrane Systematic Reviews, 10-Jul-2012
Genital ulcer disease by virtue of disruption of the mucosal surfaces may enhance HIV acquisition. Genital ulcer disease treatment with resolution of the ulcers may therefore contribute in reducing the sexual acquisition of HIV. - Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
Cochrane Systematic Reviews, 10-Nov-2017
Common fetal aneuploidies include Down syndrome (trisomy 21 or T21), Edward syndrome (trisomy 18 or T18), Patau syndrome (trisomy 13 or T13), Turner syndrome (45,X), Klinefelter syndrome (47,XXY), Triple X syndrome (47,XXX) and 47,XYY syndrome (47,XYY). P - GenoType® MTBDRsl assay for resistance to second‐line anti‐tuberculosis drugs
Cochrane Systematic Reviews, 8-Sep-2016
Genotype® MTBDRsl (MTBDRsl) is a rapid DNA-based test for detecting specific mutations associated with resistance to fluoroquinolones and second-line injectable drugs (SLIDs) in Mycobacterium tuberculosis complex. MTBDRsl version 2.0 (released in 2015) id - Ghrelin for the management of cachexia associated with cancer
Cochrane Systematic Reviews, 28-Feb-2018
Cancer sufferers are amongst the most malnourished of all the patient groups. Studies have shown that ghrelin, a gut hormone can be a potential therapeutic agent for cachexia (wasting syndrome) associated with cancer. A variety of mechanisms of action of - Ginkgo biloba extract for age‐related macular degeneration
Cochrane Systematic Reviews, 31-Jan-2013
Ginkgo is used in the treatment of peripheral vascular disease and 'cerebral insufficiency'. It is thought to have several potential mechanisms of action including increased blood flow, platelet activating factor antagonism, and prevention of membrane dam - Ginkgo biloba for acute ischaemic stroke
Cochrane Systematic Reviews, 19-Oct-2005
Ginkgo biloba extract is widely used in the treatment of acute ischaemic stroke in China. We aimed to assess the evidence from randomised controlled trials and quasi-randomised controlled trials on the use of Ginkgo biloba extract in acute ischaemic strok - Ginkgo biloba for cognitive impairment and dementia
Cochrane Systematic Reviews, 21-Jan-2009
Products of the maidenhair tree, Ginkgo biloba, have long been used in China as a traditional medicine for various disorders of health. A standardized extract is widely used in the West for the treatment of a range of conditions including memory and conce - Ginkgo biloba for intermittent claudication
Cochrane Systematic Reviews, 7-Jun-2013
People with intermittent claudication (IC) suffer from pain in the muscles of the leg occurring during exercise which is relieved by a short period of rest. Symptomatic relief can be achieved by (supervised) exercise therapy and pharmacological treatments - Ginkgo biloba for tinnitus
Cochrane Systematic Reviews, 15-Feb-2013
This is an update of a Cochrane review first published in The Cochrane Library in Issue 2, 2004 and previously updated in 2007 and 2009. - Ginseng for cognition
Cochrane Systematic Reviews, 9-Nov-2010
Ginseng is a herbal medicine in widespread use throughout the world. Its effect on the brain and nervous system has been investigated. It has been suggested, on the basis of both laboratory and clinical studies, that it may have beneficial effects on cogn - Ginseng for erectile dysfunction
Cochrane Systematic Reviews, 19-Apr-2021
Dietary supplements with ginseng, or ginseng alone, are widely used for a broad range of conditions, including erectile dysfunction. Ginseng is particularly popular in Asian countries. Individual studies assessing its effects are mostly small, of uneven m - Giving women their own case notes to carry during pregnancy
Cochrane Systematic Reviews, 14-Oct-2015
In many countries women are given their own case notes to carry during pregnancy to increase their sense of control over, and satisfaction with, their care.
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