- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Postoperative administration of non-steroidal anti-inflammatory drugs (NSAIDs) reduces patient opioid requirements and, in turn, reduces the incidence and severity of opioid-induced adverse events (AEs). - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Cerivastatin was the most potent statin until it was withdrawn from the market due to a number of fatalities due to rhabdomyolysis, however, the dose-related magnitude of effect of cerivastatin on blood lipids is not known. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Remote ischaemic conditioning (RIC) has been developed as a neuroprotective strategy to prevent and treat ischaemic stroke. It usually involves restricting blood flow to limbs and then releasing the ischaemic blood to promote a neuroprotective effect. Pre - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Children with motor disorders can have difficulties in producing accurate and consistent movements for speech, gesture or facial expression (or a combination of these), making their communication difficult to understand. Parents may be offered training to - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Tramadol is an opioid analgesic licensed for use in moderate to severe pain. It is considered as a low risk for abuse, so control regulations are not as stringent as for 'strong' opioids such as morphine. It has a potential role as a step 2 option of the - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Chronic pain is common and can be challenging to manage. Despite increased utilisation of opioids, the safety and efficacy of long-term use of these compounds for chronic non-cancer pain (CNCP) remains controversial. This overview of Cochrane Reviews comp - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Diagnoses of endometrial cancer are increasing secondary to the rising prevalence of obesity. Obesity plays an important role in promoting the development of endometrial cancer, by inducing a state of unopposed oestrogen excess, insulin resistance and inf - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Congenital adrenal hyperplasia (CAH) is an autosomal recessive condition which leads to glucocorticoid deficiency and is the most common cause of adrenal insufficiency in children. In over 90% of cases, 21-hydroxylase enzyme deficiency is found which is c - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Social networking sites (SNSs) have great potential as a platform for public health interventions to address the unmet need for contraception. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Resilience can be defined as the maintenance or quick recovery of mental health during or after periods of stressor exposure, which may result from a potentially traumatising event, challenging life circumstances, a critical life transition phase, or phys - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
An increasing number of people survive cancer but a significant proportion have gastrointestinal side effects as a result of radiotherapy (RT), which impairs their quality of life (QoL). - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Irritable bowel syndrome (IBS) is a prevalent condition that currently lacks highly effective therapies for its management. Biofeedback has been proposed as a therapy that may help individuals learn to exert conscious control over sympatho-vagal balance a - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Maintaining care for ill persons in the community is heavily dependent on support from unpaid caregivers. Many caregivers, however, find themselves in a caring role for which they are ill prepared and may require professional support. The telephone is an - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract, in which the pathogenesis is believed to be partly influenced by the gut microbiome. Probiotics can be used to manipulate the microbiome and have therefore been conside - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Functional endoscopic sinus surgery (FESS) is a minimally invasive technique that is used to treat chronic sinusitis. Small bleeding areas can reduce operative visibility and result in destruction of surrounding structures. Deliberate hypotension (lowerin - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
In many countries of the industrialised world second generation (atypical) antipsychotics have become first line drug treatments for people with schizophrenia. The question as to whether, and if so how much, the effects of the various second generation an - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Patients undergoing neurosurgery are at risk of cerebral ischaemia with resultant cerebral hypoxia and neuronal cell death. This can increase both the risk of mortality and long term neurological disability. Induced hypothermia has been shown to reduce th - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Otitis media is inflammation of the middle ear and is usually caused by infection. It affects people of all ages but is particularly common in young children. Around 164 million people worldwide have long-term hearing loss caused by this condition, 90% of - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Tranexamic acid reduces haemorrhage through its antifibrinolytic effects. In a previous version of the present review, we found that tranexamic acid may reduce mortality. This review includes updated searches and new trials. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Mother-infant proximity and interactions after birth and during the early postpartum period are important for breast-milk production and breastfeeding success. Rooming-in and separate care are both traditional practices. Rooming-in involves keeping the mo
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