- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Scleroderma is a connective tissue disease causing fibrosis and commonly affects the skin and internal organs such as the GI tract, lungs, kidney and heart. Most people with scleroderma also have Raynaud's phenomenon (RP). One of the possible treatment op - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Raynaud's is a vasodilatory phenomenon characterised by digital pallor, cyanosis and pain of the extremities. Primary Raynaud's phenomenon has no underlying disease associated with it, while secondary Raynaud's phenomenon is associated with conective tiss - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Scleroderma is a connective tissue disease causing fibrosis and commonly affects the skin and internal organs such as the GI tract, lungs, kidney and heart. Most people with scleroderma also have raynaud's phenomenon (RP). One of the possible treatment op - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Methotrexate is a folic acid antagonist widely used for the treatment of neoplastic disorders. Methotrexate inhibits the synthesis of deoxyribonucleic acid (DNA), ribonucleic acid (RNA) and proteins by binding to dihydrofolate reductase. Currently, methot - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Sulfasalazine has become a common second line drug (DMARD) for the treatment of rheumatoid arthritis (RA). - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
No cure for rheumatoid arthritis (RA) is known at present, so treatment often focuses on management of symptoms such as pain, stiffness and mobility. Treatment options include pharmacological interventions, physical therapy treatments and balneotherapy. B - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Gold compounds have been used in several conditions affecting man since the 18th century (tuberculosis, lupus vulgaris, bacterial endocarditis, etc.) however, in the past decade the use of injectable gold for rheumatoid arthritis has markedly declined, an - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
The majority of people with hip fracture are treated surgically, requiring anaesthesia. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Many different surgical techniques have been described for the internal fixation of extracapsular hip fractures. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Isolated fractures of the shaft of the ulna, which are often sustained when the forearm is raised to shield against a blow, are generally treated on an outpatient basis. This is an update of a Cochrane review first published in 1998 and last updated in 20 - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Medication used for acute aggression in psychiatry must have rapid onset of effect, low frequency of administration and low levels of adverse effects. Zuclopenthixol acetate is said to have these properties. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Umbilical arterial catheters (UACs) are among the most commonly used monitoring methodologies in neonatal intensive care. There seems to be significant variance between neonatal intensive care units in exactly how these catheters are used. This variance i - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Following a period of mechanical ventilation, post-extubation upper airway obstruction can occur in newborn infants, especially after prolonged, traumatic or multiple intubations. The subsequent increase in upper airway resistance may lead to respiratory - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Umbilical arterial catheters (UACs) are among the most commonly used monitoring methodologies in neonatal intensive care. There seems to be significant variance between neonatal intensive care units in exactly how these catheters are used. This variance i - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Umbilical arterial catheters (UACs) are among the most commonly used monitoring methodologies in neonatal intensive care. Immediately after insertion of a UAC, local vascular compromise is frequently evident, usually in the form of blue or white toes, but - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Inhaled nitric oxide (iNO) is effective in term infants with hypoxic respiratory failure. The pathophysiology of respiratory failure and the potential risks of iNO differ substantially in preterm infants, necessitating specific study in this population. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Respiratory distress syndrome (RDS) is caused by a deficiency or dysfunction of pulmonary surfactant. A variety of animal derived surfactant extracts have been formulated and given to infants at risk of developing RDS. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Stroke is a leading cause of death and disability world wide. Thrombolysis with recombinant tissue plasminogen activator (rt-PA) is licensed for treatment of acute ischaemic stroke in the early hours after symptom onset. It has been shown in randomised co - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Carotid artery stenting is an alternative to carotid endarterectomy for the treatment of atherosclerotic carotid artery stenosis. This review updates a previous version first published in 1997 and subsequently updated in 2004, 2007, and 2012. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Surgery for vertebral artery stenosis is technically difficult, potentially hazardous and is not considered in most centres. There is growing evidence from case series that vertebral artery stenosis may be treated endovascularly by percutaneous translumin
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