- Fibrin sealants for the prevention of postoperative pancreatic fistula following pancreatic surgery
Cochrane Systematic Reviews, 11-Mar-2020
Postoperative pancreatic fistula is one of the most frequent and potentially life-threatening complications following pancreatic resections. Fibrin sealants have been used in some centers to reduce postoperative pancreatic fistula. However, the use of fib - Fibrinogen concentrate in bleeding patients
Cochrane Systematic Reviews, 29-Aug-2013
Hypofibrinogenaemia is associated with increased morbidity and mortality, but the optimal treatment level, the use of preemptive treatment and the preferred source of fibrinogen remain disputed. Fibrinogen concentrate is increasingly used and recommended - Fibrinogen depleting agents for acute ischaemic stroke
Cochrane Systematic Reviews, 31-Oct-2013
Fibrinogen depleting agents reduce fibrinogen in blood plasma, reduce blood viscosity and hence increase blood flow. This may help remove the blood clot blocking the artery and re-establish blood flow to the affected area of the brain after an ischaemic s - Fibrinolytic agents for peripheral arterial occlusion
Cochrane Systematic Reviews, 18-Dec-2013
Peripheral arterial thrombolysis is used in the management of peripheral arterial ischaemia. Streptokinase was originally used but safety concerns led to a search for other agents. Urokinase and recombinant tissue plasminogen activator (rt-PA) have increa - Fibrinolytic therapy for intraventricular hemorrhage in adults
Cochrane Systematic Reviews, 22-Jul-2002
Spontaneous or secondary intraventricular hemorrhage is a marker of poor prognosis for hemorrhagic stroke. It can cause hydrocephalus and require ventricular shunt placement, result in permanent neurological deficits or death. Fibrinolytic agents injected - Final‐impression techniques and materials for making complete and removable partial dentures
Cochrane Systematic Reviews, 4-Apr-2018
Edentulism is relatively common and is often treated with the provision of complete or partial removable dentures. Clinicians make final impressions of complete dentures (CD) and removable partial dentures (RPD) using different techniques and materials. A - Financial arrangements for health systems in low‐income countries: an overview of systematic reviews
Cochrane Systematic Reviews, 11-Sep-2017
One target of the Sustainable Development Goals is to achieve "universal health coverage, including financial risk protection, access to quality essential health-care services and access to safe, effective, quality and affordable essential medicines and v - Financial benefits for child health and well‐being in low income or socially disadvantaged families in developed world countries
Cochrane Systematic Reviews, 23-Apr-2008
A strong and consistent relationship has been observed between relative poverty and poor child health and well-being even among rich nations. This review set out to examine evidence that additional monies provided to poor or disadvantaged families may ben - Financial interventions and movement restrictions for managing the movement of health workers between public and private organizations in low- and middle-income countries
Cochrane Systematic Reviews, 10-Feb-2014
Health workers move between public and private organizations in both urban and rural areas during the course of their career. Depending on the proportion of the population served by public or private organizations in a particular setting, this movement ma - Finasteride for benign prostatic hyperplasia
Cochrane Systematic Reviews, 6-Oct-2010
Benign prostatic hyperplasia (BPH), a non-malignant enlargement of the prostate in aging men, can cause bothersome urinary symptoms (intermittency, weak stream, straining, urgency, frequency, incomplete emptying). Finasteride, a five-alpha reductase inhib - Fingolimod for relapsing-remitting multiple sclerosis
Cochrane Systematic Reviews, 15-Apr-2016
Fingolimod was approved in 2010 for the treatment of patients with the relapsing-remitting (RR) form of multiple sclerosis (MS). It was designed to reduce the frequency of exacerbations and to delay disability worsening. Issues on its safety and efficacy, - First aid glucose administration routes for symptomatic hypoglycaemia
Cochrane Systematic Reviews, 11-Apr-2019
Hypoglycaemia is a common occurrence in people with diabetes but can also result from an imbalance in glucose homeostasis in the absence of diabetes. The best enteral route for glucose administration for suspected hypoglycaemia in a first aid situation is - First aid interventions by laypeople for acute oral poisoning
Cochrane Systematic Reviews, 19-Dec-2018
Oral poisoning is a major cause of mortality and disability worldwide, with estimates of over 100,000 deaths due to unintentional poisoning each year and an overrepresentation of children below five years of age. Any effective intervention that laypeople - First and second trimester serum tests with and without first trimester ultrasound tests for Down's syndrome screening
Cochrane Systematic Reviews, 15-Mar-2017
Down's syndrome occurs when a person has three copies of chromosome 21 (or the specific area of chromosome 21 implicated in causing Down's syndrome) rather than two. It is the commonest congenital cause of mental disability. Non-invasive screening based o - First rank symptoms for schizophrenia
Cochrane Systematic Reviews, 25-Jan-2015
Early and accurate diagnosis and treatment of schizophrenia may have long-term advantages for the patient; the longer psychosis goes untreated the more severe the repercussions for relapse and recovery. If the correct diagnosis is not schizophrenia, but a - First trimester serum tests for Down's syndrome screening
Cochrane Systematic Reviews, 30-Nov-2015
Down's syndrome occurs when a person has three, rather than two copies of chromosome 21; or the specific area of chromosome 21 implicated in causing Down's syndrome. It is the commonest congenital cause of mental disability and also leads to numerous meta - First trimester ultrasound tests alone or in combination with first trimester serum tests for Down's syndrome screening
Cochrane Systematic Reviews, 15-Mar-2017
Down's syndrome occurs when a person has three, rather than two copies of chromosome 21; or the specific area of chromosome 21 implicated in causing Down's syndrome. It is the commonest congenital cause of mental disability and also leads to numerous meta - First-line allogeneic hematopoietic stem cell transplantation of HLA-matched sibling donors compared with first-line ciclosporin and/or antithymocyte or antilymphocyte globulin for acquired severe aplastic anemia
Cochrane Systematic Reviews, 19-Jul-2013
Acquired severe aplastic anemia is a rare and potentially fatal disease, which is characterized by hypocellular bone marrow and pancytopenia. The major signs and symptoms are severe infections, bleeding, and exhaustion. First-line allogeneic hematopoietic - First-line beta-blockers versus other antihypertensive medications for chronic type B aortic dissection
Cochrane Systematic Reviews, 26-Feb-2014
Thoracic aortic dissection (TAD) is a severe and often lethal complication in people with hypertension. Current practice in the treatment of chronic type B aortic dissections is the use of beta-blockers as first-line therapy to decrease aortic wall stress - First‐line chemotherapy in low‐risk gestational trophoblastic neoplasia
Cochrane Systematic Reviews, 9-Jun-2016
This is the second update of a Cochrane review that was first published in 2009, Issue 1. Gestational trophoblastic neoplasia (GTN) is a rare but curable disease arising in the fetal chorion during pregnancy. Most women with low-risk GTN will be cured by
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