- Extracorporeal photopheresis versus alternative treatment for chronic graft‐versus‐host disease after haematopoietic stem cell transplantation in children and adolescents
Cochrane Systematic Reviews, 9-Jun-2022
Chronic graft-versus-host disease (cGvHD) is a major cause of morbidity and mortality after haematopoietic stem cell transplantation, occurring in 6% to 65% of the paediatric recipients. Currently, the therapeutic mainstay for cGvHD is treatment with cort - Extracorporeal photopheresis versus standard treatment for acute graft‐versus‐host disease after haematopoietic stem cell transplantation in children and adolescents
Cochrane Systematic Reviews, 27-Sep-2022
Acute graft-versus-host disease (aGvHD) is a major cause of morbidity and mortality after haematopoietic stem cell transplantation (HSCT), occurring in 8% to 85% of paediatric recipients. Currently, the therapeutic mainstay for aGvHD is treatment with cor - Extracorporeal shock wave lithotripsy (ESWL) versus percutaneous nephrolithotomy (PCNL) or retrograde intrarenal surgery (RIRS) for kidney stones
Cochrane Systematic Reviews, 17-Nov-2014
Stones in the urinary tract are a common medical problem in the general population. At present, the great expansion in minimally invasive techniques has led to the decrease in open surgery. Extracorporeal shock wave lithotripsy (ESWL) has been introduced - Extracorporeal shock wave lithotripsy (ESWL) versus ureteroscopic management for ureteric calculi
Cochrane Systematic Reviews, 16-May-2012
Ureteral stones frequently cause renal colic, and if left untreated, can lead to obstructive uropathy. Extracorporeal shock wave lithotripsy (ESWL) and ureteroscopy, with or without intracorporeal lithotripsy, are the most common interventions used to tre - Extracorporeal shock wave therapy for the healing and management of venous leg ulcers
Cochrane Systematic Reviews, 11-Jun-2018
Leg ulcers are chronic wounds of the lower leg, caused by poor blood flow, that can take a long time to heal. The pooling of blood in the veins can damage the skin and surrounding tissues, causing an ulcer to form. Venous leg ulcers are associated with im - Extracranial‐intracranial arterial bypass surgery for occlusive carotid artery disease
Cochrane Systematic Reviews, 17-Feb-2010
The EC/IC Bypass Study Group found no benefit of extracranial to intracranial (EC/IC) bypass surgery over medical therapy in patients with symptomatic carotid artery occlusion (sCAO). However, the study was criticised for many reasons and the real effect - Extraction of primary (baby) teeth for unerupted palatally displaced permanent canine teeth in children
Cochrane Systematic Reviews, 8-Mar-2018
The permanent canine tooth in the maxillary (upper) jaw sometimes does not erupt into the mouth correctly. In about 1% to 3% of the population these teeth will be diverted into the roof of the mouth (palatally). It has been suggested that if the primary c - Extramedullary fixation implants and external fixators for extracapsular hip fractures in adults
Cochrane Systematic Reviews, 28-Feb-2013
Extramedullary fixation of hip fractures involves the application of a plate and screws to the lateral side of the proximal femur. In external fixators, the stabilising component is held outside the thigh by pins or screws driven into the bone. This is an - Extubation from low‐rate intermittent positive airway pressure versus extubation after a trial of endotracheal continuous positive airway pressure in intubated preterm infants
Cochrane Systematic Reviews, 23-Oct-2001
Failure of extubation and subsequent reintubation may result in additional stress and trauma to the premature infant. Treating infants about to be extubated with a period of endotracheal CPAP has been suggested as a method of preparing for extubation. How - Ezetimibe for the prevention of cardiovascular disease and all-cause mortality events
Cochrane Systematic Reviews, 19-Nov-2018
Cardiovascular disease (CVD) remains an important cause of mortality and morbidity, and high levels of blood cholesterol are thought to be the major modifiable risk factors for CVD. The use of statins is the preferred treatment strategy for the prevention - Face washing promotion for preventing active trachoma
Cochrane Systematic Reviews, 20-Feb-2015
Trachoma remains a major cause of avoidable blindness among underprivileged populations in many developing countries. It is estimated that about 146 million people have active trachoma and nearly six million people are blind due to complications associate - Face-down positioning or posturing after macular hole surgery
Cochrane Systematic Reviews, 7-Nov-2011
Macular holes cause significant loss of central vision. With the aim of improving the outcome of surgery, a variable period of face-down positioning may be advised. - Face‐to‐face interventions for informing or educating parents about early childhood vaccination
Cochrane Systematic Reviews, 8-May-2018
Early childhood vaccination is an essential global public health practice that saves two to three million lives each year, but many children do not receive all the recommended vaccines. To achieve and maintain appropriate coverage rates, vaccination progr - Face-to-face interventions for promoting physical activity
Cochrane Systematic Reviews, 30-Sep-2013
Face-to-face interventions for promoting physical activity (PA) are continuing to be popular but their ability to achieve long term changes are unknown. - Face‐to‐face versus remote and web 2.0 interventions for promoting physical activity
Cochrane Systematic Reviews, 1-Oct-2013
Face-to-face interventions for promoting physical activity (PA) are continuing to be popular as remote and web 2.0 approaches rapidly emerge, but we are unsure which approach is more effective at achieving long term sustained change. - Factor Xa inhibitors for acute coronary syndromes
Cochrane Systematic Reviews, 14-Feb-2011
The activation of coagulation mechanisms plays a central role in the pathogenesis of acute coronary syndromes (ACS). Administration of unfractionated heparin (UFH) and low molecular weight heparins (LMWH), agents preventing the progression of thrombus for - Factor Xa inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in patients with atrial fibrillation
Cochrane Systematic Reviews, 6-Mar-2018
Factor Xa inhibitors and vitamin K antagonists (VKAs) are now recommended in treatment guidelines for preventing stroke and systemic embolic events in people with atrial fibrillation (AF). This is an update of a Cochrane review previously published in 201 - Factors influencing the uptake and use of nicotine replacement therapy and e‐cigarettes in pregnant women who smoke: a qualitative evidence synthesis
Cochrane Systematic Reviews, 22-May-2020
Nicotine replacement therapy (NRT) delivers nicotine without the toxic chemicals present in tobacco smoke. It is an effective smoking cessation aid in non-pregnant smokers, but there is less evidence of effectiveness in pregnancy. Systematic review eviden - Factors that impact on the use of mechanical ventilation weaning protocols in critically ill adults and children: a qualitative evidence‐synthesis
Cochrane Systematic Reviews, 4-Oct-2016
Prolonged mechanical ventilation is associated with a longer intensive care unit (ICU) length of stay and higher mortality. Consequently, methods to improve ventilator weaning processes have been sought. Two recent Cochrane systematic reviews in ICU adult - Factors that influence parents' and informal caregivers' views and practices regarding routine childhood vaccination: a qualitative evidence synthesis
Cochrane Systematic Reviews, 27-Oct-2021
Childhood vaccination is one of the most effective ways to prevent serious illnesses and deaths in children. However, worldwide, many children do not receive all recommended vaccinations, for several potential reasons. Vaccines might be unavailable, or pa
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