- Excimer laser refractive surgery versus phakic intraocular lenses for the correction of moderate to high myopia
Cochrane Systematic Reviews, 17-Jun-2014
Myopia is a condition in which the focusing power (refraction) of the eye is greater than that required for clear distance vision. There are two main types of surgical correction for moderate to high myopia; excimer laser and phakic intraocular lenses (IO - Excisional surgery versus ablative surgery for ovarian endometriomata
Cochrane Systematic Reviews, 13-Apr-2011
Endometriomata are endometriotic deposits within the ovary. The surgical management of these blood filled cysts is controversial. The laparoscopic approach to the management of endometriomata is favoured over a laparotomy approach as it offers the advanta - Excitatory amino acid antagonists for acute stroke
Cochrane Systematic Reviews, 21-Jul-2003
Focal cerebral ischaemia causes release of excitatory amino acid (EAA) neurotransmitters, principally glutamate, with resultant over-stimulation of EAA receptors and downstream pathways. Excess glutamate release is a pivotal event in the evolution of irre - Excitatory amino acid inhibitors for traumatic brain injury
Cochrane Systematic Reviews, 20-Jan-2003
Glutamate is the principal excitatory neurotransmitter in the brain. Injury to the brain can cause an ionic imbalance in cerebral tissue, creating an excitotoxic cascade involving glutamate and other excitatory amino acids, that leads to neuronal death in - Exenterative surgery for recurrent gynaecological malignancies
Cochrane Systematic Reviews, 21-Sep-2016
Cancer is a leading cause of death worldwide. Gynaecological cancers (i.e. cancers affecting the ovaries, uterus, cervix, vulva and vagina) are among the most common cancers in women. Unfortunately, given the nature of the disease, cancer can recur or pro - Exercise and mobilisation interventions for carpal tunnel syndrome
Cochrane Systematic Reviews, 3-May-2012
Non-surgical treatment, including exercises and mobilisation, has been offered to people experiencing mild to moderate symptoms arising from carpal tunnel syndrome (CTS). However, the effectiveness and duration of benefit from exercises and mobilisation f - Exercise for acutely hospitalised older medical patients
Cochrane Systematic Reviews, 24-Jan-2007
A high incidence of functional decline (deterioration in physical or cognitive function) during hospitalisation of older adults is reported. The role of exercise in preventing these deconditioning effects is unclear. - Exercise for cancer cachexia in adults
Cochrane Systematic Reviews, 18-Mar-2021
Cancer cachexia is a multifactorial syndrome characterised by an ongoing loss of skeletal muscle mass, with or without a loss of fat mass, leading to progressive functional impairment. Physical exercise may attenuate cancer cachexia and its impact on pati - Exercise for depression
Cochrane Systematic Reviews, 12-Sep-2013
Depression is a common and important cause of morbidity and mortality worldwide. Depression is commonly treated with antidepressants and/or psychological therapy, but some people may prefer alternative approaches such as exercise. There are a number of th - Exercise for diabetic pregnant women
Cochrane Systematic Reviews, 19-Jul-2006
Diabetes in pregnancy may result in unfavourable maternal and neonatal outcomes. Exercise was proposed as an additional strategy to improve glycaemic control. The effect of exercise during pregnancies complicated by diabetes needs to be assessed. - Exercise for dysmenorrhoea
Cochrane Systematic Reviews, 20-Sep-2019
Exercise has a number of health benefits and has been recommended as a treatment for primary dysmenorrhoea (period pain), but the evidence for its effectiveness on primary dysmenorrhoea is unclear. This review examined the available evidence supporting th - Exercise for haemophilia
Cochrane Systematic Reviews, 19-Dec-2016
Haemophilia is a bleeding disorder associated with haemorrhaging into joints and muscles. Exercise is often used to aid recovery after bleeds, and to improve joint function in the presence of arthropathy. - Exercise for hand osteoarthritis
Cochrane Systematic Reviews, 31-Jan-2017
Hand osteoarthritis (OA) is a prevalent joint disease that may lead to pain, stiffness and problems in performing hand-related activities of daily living. Currently, no cure for OA is known, and non-pharmacological modalities are recommended as first-line - Exercise for improving balance in older people
Cochrane Systematic Reviews, 5-Apr-2012
In older adults, diminished balance is associated with reduced physical functioning and an increased risk of falling. This is an update of a Cochrane review first published in 2007. - Exercise for improving outcomes after osteoporotic vertebral fracture
Cochrane Systematic Reviews, 5-Jul-2019
Vertebral fractures are associated with increased morbidity (e.g. pain, reduced quality of life) and mortality. Therapeutic exercise is a non-pharmacological conservative treatment that is often recommended for patients with vertebral fractures to reduce - Exercise for intermittent claudication
Cochrane Systematic Reviews, 26-Dec-2017
Exercise programmes are a relatively inexpensive, low-risk option compared with other, more invasive therapies for treatment of leg pain on walking (intermittent claudication (IC)). This is the fourth update of a review first published in 1998. - Exercise for osteoarthritis of the hip
Cochrane Systematic Reviews, 16-Apr-2014
Current international treatment guidelines recommending therapeutic exercise for people with symptomatic hip osteoarthritis (OA) report are based on limited evidence. - Exercise for osteoarthritis of the knee
Cochrane Systematic Reviews, 9-Jan-2015
Knee osteoarthritis (OA) is a major public health issue because it causes chronic pain, reduces physical function and diminishes quality of life. Ageing of the population and increased global prevalence of obesity are anticipated to dramatically increase - Exercise for overweight or obesity
Cochrane Systematic Reviews, 18-Oct-2006
Clinical trials have shown that exercise in adults with overweight or obesity can reduce bodyweight. There has been no quantitative systematic review of this in The Cochrane Library. - Exercise for people with high cardiovascular risk
Cochrane Systematic Reviews, 12-Aug-2014
When two or more cardiovascular risk factors occur in one individual, they may interact in a multiplicative way promoting cardiovascular disease. Exercise has proven to be effective in controlling individual risk factors but its effect on overall cardiova
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