- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Topical corticosteroids are the most frequently prescribed dermatological treatment and are often used by pregnant women with skin conditions. However, little is known about their safety in pregnancy. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Crohn's disease is a chronic relapsing condition of the alimentary tract with a high morbidity secondary to bowel inflammation. Glutamine plays a key role in maintaining the integrity of the intestinal mucosa and has been shown to reduce inflammation and - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Crohn's disease is a chronic relapsing condition of the alimentary tract with a high morbidity secondary to bowel inflammation. High levels of tumour necrosis factor-alpha (TNF-a) have been associated with the development of intestinal inflammation in Cro - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Maintenance of remission is a major issue in the management of Crohn's disease. Thalidomide, a tumour necrosis factor-alpha (TNF-a) inhibitor and its analogue, lenalidomide, may have a role in the management of Crohn's disease, but it is not clear whether - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Impaction of a soft food bolus in the oesophagus causes dysphagia and regurgitation. If the bolus does not pass spontaneously, then the patient is at risk of aspiration, dehydration, perforation, and death. Definitive management is with endoscopic interve - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Infection with human immunodeficency virus (HIV) and acquired immunodeficency syndrome (AIDS) is a pandemic that has affected millions of people globally. Although major research and clinical initiatives are addressing prevention and cure strategies, issu - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Barrett's oesophagus is one of the most common pre-malignant lesions in the world. Currently the mainstay of therapy is surgical management of advanced cancer but this has improved the five-year survival very little since the 1980s. As a consequence, impr - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Arthritis remains a relatively infrequent complication of cystic fibrosis, but is a cause of significant morbidity when it does occur. Two distinct types of arthritis are described in cystic fibrosis: cystic fibrosis-related arthropathy and hypertrophic o - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Blood loss during liver resection is considered one of the most important factors affecting the peri-operative outcomes of patients undergoing liver resection. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Alcoholic hepatitis is a life-threatening disease, with an average mortality of approximately 40%. There is no widely accepted, effective treatment for alcoholic hepatitis. Pentoxifylline is used to treat alcoholic hepatitis, but there has been no systema - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Nonalcoholic fatty liver disease (NAFLD) is increasingly recognised as a condition associated with overweight or obesity that may progress to end-stage liver disease. NAFLD histology resembles alcohol-induced liver injury, but occurs in patients with no h - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Leptospira infection is a global zoonosis with significant health impact for agricultural workers and those persons whose work or recreation takes them into endemic areas. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Although highly effective in the treatment of obstructive sleep apnoea (OSA), continuous positive airway pressure (CPAP) is not universally accepted by users. Educational, supportive and behavioural interventions may help people with OSA initiate and main - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Hyperopia in infancy requires accommodative effort to bring images into focus. Prolonged accommodative effort has been associated with an increased risk of strabismus. Strabismus may result in asthenopia and intermittent diplopia, and makes near work task - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
A hordeolum is a common, painful inflammation of the eyelid margin that is usually caused by a bacterial infection. The infection affects oil glands of the eyelid and can be either internal or external. In many cases, the lesion drains spontaneously and r - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Respiratory syncytial virus infection causes acute lung infection in infants and young children worldwide, resulting in considerable morbidity and mortality. Children with cystic fibrosis are prone to recurrent lung inflammation, bacterial colonisation an - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Idiopathic thrombocytopenic purpura (ITP) is a common hematologic disorder caused by immune-mediated thrombocytopenia. The magnitude of the maternal-fetal risk of ITP during pregnancy is controversial. Labour management of pregnant women with ITP remains - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
While most guidance recommends the use of insulin in women whose pregnancies are affected by pre-existing diabetes, oral anti-diabetic agents may be more acceptable to women. The effects of these oral anti-diabetic agents on maternal and infant health out - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Antipsychotic agents are often used to treat neuropsychiatric symptoms (NPS) in people with dementia although there is uncertainty about the effectiveness of their long-term use for this indication and concern that they may cause harm, including higher mo - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Bronchiectasis is a common respiratory disease, especially in developing countries. Its cause varies from chronic infection to rare immune deficiencies. Bronchiectasis can be present with other respiratory diseases, such as chronic obstructive pulmonary d
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