- Epidural pain relief versus systemic opioid‐based pain relief for abdominal aortic surgery
Cochrane Systematic Reviews, 5-Jan-2016
Epidural analgesia offers greater pain relief compared to systemic opioid-based medications, but its effect on morbidity and mortality is unclear. This review was originally published in 2006 and was updated in 2012 and again in 2016. - Epidural therapy for the treatment of severe pre‐eclampsia in non labouring women
Cochrane Systematic Reviews, 28-Nov-2017
Pre-eclampsia is a pregnancy-specific multi-organ disorder, which is characterised by hypertension and multisystem organ involvement and which has significant maternal and fetal morbidity and mortality. Failure of the placental vascular remodelling and re - Epidural versus non‐epidural or no analgesia for pain management in labour
Cochrane Systematic Reviews, 21-May-2018
Epidural analgesia is a central nerve block technique achieved by injection of a local anaesthetic close to the nerves that transmit pain, and is widely used as a form of pain relief in labour. However, there are concerns about unintended adverse effects - Epilepsy clinics versus general neurology or medical clinics
Cochrane Systematic Reviews, 25-Oct-2008
Epilepsy is the most common serious neurological condition after stroke, with a 0.5% prevalence, and a two to three per cent life time risk of being given a diagnosis of epilepsy in the developed world. - Epinephrine for bronchiolitis
Cochrane Systematic Reviews, 2-May-2011
Bronchodilators are commonly used for acute bronchiolitis, despite uncertain effectiveness. - Epinephrine for the resuscitation of apparently stillborn or extremely bradycardic newborn infants
Cochrane Systematic Reviews, 22-Jul-2002
Epinephrine is a cardiac stimulant with complex effects on the heart and blood vessels. It has been used for decades in all age groups to treat cardiac arrest and bradycardia. Despite formal guidelines for the use of epinephrine in neonatal resuscitation, - Epinephrine for transient tachypnea of the newborn
Cochrane Systematic Reviews, 23-May-2016
Transient tachypnea of the newborn is characterized by tachypnea and signs of respiratory distress. Transient tachypnea typically appears within the first two hours of life in term and late preterm newborns. Although transient tachypnea of the newborn is - Epinephrine injection versus epinephrine injection and a second endoscopic method in high-risk bleeding ulcers
Cochrane Systematic Reviews, 9-Oct-2014
Endoscopic therapy reduces the rebleeding rate and the need for surgery in patients with bleeding peptic ulcers. - Eplerenone for hypertension
Cochrane Systematic Reviews, 28-Feb-2017
Eplerenone is an aldosterone receptor blocker that is chemically derived from spironolactone. In Canada, it is indicated for use as adjunctive therapy to reduce mortality for heart failure patients with New York Heart Association (NYHA) class II systolic - Equivalent schedules of intradermal fractional dose versus intramuscular full dose of inactivated polio vaccine for prevention of poliomyelitis
Cochrane Systematic Reviews, 19-Dec-2019
Poliomyelitis is a debilitating and deadly infection. Despite exponential growth in medical science, there is still no cure for the disease, which is caused by three types of wild polioviruses: types 1, 2, and 3. According to the Global Polio Eradication - Eradication therapy for Burkholderia cepacia complex in people with cystic fibrosis
Cochrane Systematic Reviews, 18-Apr-2019
Chronic infection with Burkholderia cepacia complex species remains a significant problem for clinicians treating people with cystic fibrosis. Colonisation with Burkholderia cepacia complex species is linked to a more rapid decline in lung function and in - Eradication therapy for peptic ulcer disease in Helicobacter pylori‐positive people
Cochrane Systematic Reviews, 19-Apr-2016
Peptic ulcer disease is the cause of dyspepsia in about 10% of people. Ninety-five percent of duodenal and 70% of gastric ulcers are associated with Helicobacter pylori. Eradication of H. pylori reduces the relapse rate of ulcers but the magnitude of this - Ergonomic and physiotherapeutic interventions for treating work-related complaints of the arm, neck or shoulder in adults
Cochrane Systematic Reviews, 20-Jan-2010
Conservative interventions such as physiotherapy and ergonomic adjustments (such as keyboard adjustments or ergonomic advice) play a major role in the treatment of most work-related complaints of the arm, neck or shoulder (CANS). - Ergonomic interventions for preventing musculoskeletal disorders in dental care practitioners
Cochrane Systematic Reviews, 15-Oct-2018
Dentistry is a profession with a high prevalence of work-related musculoskeletal disorders (WMSD) among practitioners, with symptoms often starting as early in the career as the student phase. Ergonomic interventions in physical, cognitive, and organisati - Ergonomic interventions for preventing work‐related musculoskeletal disorders of the upper limb and neck among office workers
Cochrane Systematic Reviews, 23-Oct-2018
Work-related upper limb and neck musculoskeletal disorders (MSDs) are one of the most common occupational disorders worldwide. Studies have shown that the percentage of office workers that suffer from MSDs ranges from 20 to 60 per cent. The direct and ind - Ergonomic positioning or equipment for treating carpal tunnel syndrome
Cochrane Systematic Reviews, 18-Jan-2012
Non-surgical treatment, including ergonomic positioning or equipment, are sometimes offered to people experiencing mild to moderate symptoms from carpal tunnel syndrome (CTS). The effectiveness and duration of benefit from ergonomic positioning or equipme - Erythromycin for the prevention and treatment of feeding intolerance in preterm infants
Cochrane Systematic Reviews, 8-May-2008
Functional immaturity of gastrointestinal motility predisposes preterm infants to feeding intolerance. Erythromycin is a motilin agonist that exerts its prokinetic effect by stimulating propagative contractile activity in the interdigestive phase. - Erythromycin for the prevention of chronic lung disease in intubated preterm infants at risk for, or colonized or infected with Ureaplasma urealyticum
Cochrane Systematic Reviews, 22-Oct-2008
Controversy exists over whether or not Ureaplasma urealyticum colonization or infection of the respiratory tract contributes to the severity of chronic lung disease (CLD), a major cause of morbidity and mortality in preterm infants. - Erythropoiesis-stimulating agents for anaemia in adults with chronic kidney disease: a network meta-analysis
Cochrane Systematic Reviews, 3-Dec-2014
Several erythropoiesis-stimulating agents (ESAs) are available for treating anaemia in people with chronic kidney disease (CKD). Their relative efficacy (preventing blood transfusions and reducing fatigue and breathlessness) and safety (mortality and card - Erythropoiesis‐stimulating agents for anaemia in chronic heart failure patients
Cochrane Systematic Reviews, 20-Jan-2010
Chronic heart failure (CHF) is a leading cause of morbidity and mortality worldwide. Anaemia is a common (12-55%) co-morbid condition and is associated with worsening symptoms and increased mortality. Anaemia is treatable and can be targeted in the treatm
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